7YY8

Crystal structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with Fragment 12

Summary for 7YY8

Entry DOI	10.2210/pdb7yy8/pdb
Descriptor	Phosphopantetheine adenylyltransferase, 3-(INDOL-3-YL) LACTATE, (2R)-2-hydroxy-3-(1H-indol-3-yl)propanoic acid, ... (4 entities in total)
Functional Keywords	coad, ppat, nucleotidyltransferase, transferase
Biological source	Mycobacteroides abscessus
Total number of polymer chains	3
Total formula weight	52841.08
Authors	Thomas, S.E.,Coyne, A.G.,Blundell, T.L. (deposition date: 2022-02-17, release date: 2022-06-29, Last modification date: 2024-01-31)
Primary citation	Thomas, S.E.,McCarthy, W.J.,El Bakali, J.,Brown, K.P.,Kim, S.Y.,Blaszczyk, M.,Mendes, V.,Abell, C.,Floto, R.A.,Coyne, A.G.,Blundell, T.L. Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design. Front Mol Biosci, 9:880432-880432, 2022 Cited by PubMed: 35712348 DOI: 10.3389/fmolb.2022.880432 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.516 Å)

Structure validation