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3QTE
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BU of 3qte by Molmil
Crystal structure of human alpha-defensin 6 (H27W mutant)
Descriptor: CHLORIDE ION, Defensin-6, GLYCEROL
Authors:Pazgier, M, Lu, W.
Deposit date:2011-02-22
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Human alpha-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets.
Science, 337, 2012
5YPB
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BU of 5ypb by Molmil
p62/SQSTM1 ZZ domain with His-peptide
Descriptor: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
5YPH
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BU of 5yph by Molmil
p62/SQSTM1 ZZ domain with Ile-peptide
Descriptor: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.629 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
5YP8
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BU of 5yp8 by Molmil
p62/SQSTM1 ZZ domain with Arg-peptide
Descriptor: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.448 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
5YPG
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BU of 5ypg by Molmil
p62/SQSTM1 ZZ domain with Leu-peptide
Descriptor: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
7U69
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BU of 7u69 by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Phenethyl Piperidine-4-acrylhydroxamic Acid Inhibitor
Descriptor: (2E)-N-hydroxy-3-[1-(2-phenylethyl)piperidin-4-yl]prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-03
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
7U3M
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BU of 7u3m by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with N-methylpiperazine Benzhydroxamic Acid
Descriptor: N-hydroxy-4-[(4-methylpiperazin-1-yl)methyl]benzamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-02-27
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
7U6A
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BU of 7u6a by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 3-thienylmethyl Benzhydroxamic Acid Inhibitor
Descriptor: 1,2-ETHANEDIOL, N-hydroxy-4-({[(thiophen-3-yl)methyl]amino}methyl)benzamide, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-03
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
5MT3
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BU of 5mt3 by Molmil
Human insulin in complex with serotonin and arginine
Descriptor: ARGININE, CHLORIDE ION, Insulin, ...
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2017-01-06
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
5MT9
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BU of 5mt9 by Molmil
Human insulin in complex with serotonin and arginine
Descriptor: ARGININE, CHLORIDE ION, Insulin, ...
Authors:Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L.
Deposit date:2017-01-07
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
J. Biol. Chem., 292, 2017
7U6B
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BU of 7u6b by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Indolethyl Piperidine-4-acrylhydroxamic Acid Inhibitor
Descriptor: (2E)-N-hydroxy-3-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-03
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
5YPF
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BU of 5ypf by Molmil
p62/SQSTM1 ZZ domain with Trp-peptide
Descriptor: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
5JST
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BU of 5jst by Molmil
MBP fused MDV1 coiled coil
Descriptor: ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein,Mitochondrial division protein 1, ...
Authors:Kim, B.-W, Song, H.K.
Deposit date:2016-05-09
Release date:2017-03-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:ACCORD: an assessment tool to determine the orientation of homodimeric coiled-coils.
Sci Rep, 7, 2017
5NJR
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BU of 5njr by Molmil
Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 50s time-delay, phased with 4ET8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ...
Authors:Oberthuer, D, Meents, A, Beyerlein, K.R, Chapman, H.N, Lieseke, J.
Deposit date:2017-03-29
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mix-and-diffuse serial synchrotron crystallography.
IUCrJ, 4, 2017
5YPE
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BU of 5ype by Molmil
p62/SQSTM1 ZZ domain with Tyr-peptide
Descriptor: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
7U59
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BU of 7u59 by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Piperidine-4-hydroxamic acid Inhibitor
Descriptor: 1,2-ETHANEDIOL, 1-[2-(benzylamino)ethyl]-N-hydroxypiperidine-4-carboxamide, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-01
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement.
Chembiochem, 23, 2022
5YPA
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BU of 5ypa by Molmil
p62/SQSTM1 ZZ domain with Lys-peptide
Descriptor: 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
5YP7
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BU of 5yp7 by Molmil
p62/SQSTM1 ZZ domain
Descriptor: Sequestosome-1, ZINC ION
Authors:Kwon, D.H, Kim, L, Song, H.K.
Deposit date:2017-11-01
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.424 Å)
Cite:Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter.
Nat Commun, 9, 2018
1NE3
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BU of 1ne3 by Molmil
Solution structure of ribosomal protein S28E from Methanobacterium Thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH0256_1_68; Northeast Structural Genomics Target TT744
Descriptor: 30S ribosomal protein S28E
Authors:Wu, B, Pineda-Lucena, A, Yee, A, Cort, J.R, Ramelot, T.A, Kennedy, M, Edwards, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-12-10
Release date:2003-12-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of ribosomal protein S28E from Methanobacterium thermoautotrophicum.
Protein Sci., 12, 2003
5JU7
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BU of 5ju7 by Molmil
DNA BINDING DOMAIN OF E.COLI CADC
Descriptor: Transcriptional activator CadC, ZINC ION
Authors:Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
Deposit date:2016-05-10
Release date:2017-04-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.
Sci Rep, 7, 2017
1OVO
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BU of 1ovo by Molmil
CRYSTALLOGRAPHIC REFINEMENT OF JAPANESE QUAIL OVOMUCOID, A KAZAL-TYPE INHIBITOR, AND MODEL BUILDING STUDIES OF COMPLEXES WITH SERINE PROTEASES
Descriptor: OVOMUCOID THIRD DOMAIN
Authors:Weber, E, Papamokos, E, Bode, W, Huber, R, Kato, I, Laskowskijunior, M.
Deposit date:1982-01-18
Release date:1982-05-26
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic refinement of Japanese quail ovomucoid, a Kazal-type inhibitor, and model building studies of complexes with serine proteases.
J.Mol.Biol., 158, 1982
8AXW
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BU of 8axw by Molmil
The structure of mouse AsterC (GramD1c) with Ezetimibe
Descriptor: (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, CHLORIDE ION, ETHANOL, ...
Authors:Fairall, L, Xiao, X, Burger, L, Tontonoz, P, Schwabe, J.W.R.
Deposit date:2022-09-01
Release date:2023-09-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Science, 382, 2023
5UIC
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BU of 5uic by Molmil
Structure of the Francisella response regulator receiver domain, QseB
Descriptor: Two-component response regulator
Authors:Allen, C.L, Milton, M.E, Cavanagh, J.
Deposit date:2017-01-13
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.487 Å)
Cite:Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds.
Mol. Microbiol., 106, 2017
8BAH
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BU of 8bah by Molmil
Human Mre11-Nbs1 complex
Descriptor: Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin
Authors:Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P.
Deposit date:2022-10-11
Release date:2023-01-11
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
5K5M
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BU of 5k5m by Molmil
Co-Crystal Structure of Dengue Virus Serotype 2 RNA Dependent RNA Polymerase with Compound 27
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-[(3-methoxyphenyl)sulfonyl]benzamide, RNA Dependent RNA Polymerase, ...
Authors:Arora, R, Benson, T.E.
Deposit date:2016-05-23
Release date:2016-08-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Plos Pathog., 12, 2016

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