5HNW
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![BU of 5hnw by Molmil](/molmil-images/mine/5hnw) | Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the AMPPNP state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | Deposit date: | 2016-01-19 | Release date: | 2016-08-10 | Last modified: | 2018-07-25 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
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7NB8
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![BU of 7nb8 by Molmil](/molmil-images/mine/7nb8) | Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule. | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-5, MAGNESIUM ION, ... | Authors: | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | Deposit date: | 2021-01-25 | Release date: | 2021-10-13 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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7NBA
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![BU of 7nba by Molmil](/molmil-images/mine/7nba) | Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule. | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin motor domain-containing protein,Kinesin motor domain-containing protein, MAGNESIUM ION, ... | Authors: | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | Deposit date: | 2021-01-25 | Release date: | 2021-10-13 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition. J.Biol.Chem., 297, 2021
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5HNY
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![BU of 5hny by Molmil](/molmil-images/mine/5hny) | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the AMPPNP state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | Deposit date: | 2016-01-19 | Release date: | 2016-08-10 | Last modified: | 2016-11-02 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
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7N61
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![BU of 7n61 by Molmil](/molmil-images/mine/7n61) | structure of C2 projections and MIPs | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FAP147, FAP178, ... | Authors: | Han, L, Zhang, K. | Deposit date: | 2021-06-07 | Release date: | 2022-05-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of an active central apparatus. Nat.Struct.Mol.Biol., 29, 2022
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2HXF
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![BU of 2hxf by Molmil](/molmil-images/mine/2hxf) | KIF1A head-microtubule complex structure in amppnp-form | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF1A, ... | Authors: | Kikkawa, M, Hirokawa, N. | Deposit date: | 2006-08-03 | Release date: | 2006-10-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations Embo J., 25, 2006
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2HXH
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![BU of 2hxh by Molmil](/molmil-images/mine/2hxh) | KIF1A head-microtubule complex structure in adp-form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Kikkawa, M, Hirokawa, N. | Deposit date: | 2006-08-03 | Release date: | 2006-10-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations Embo J., 25, 2006
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3EDL
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![BU of 3edl by Molmil](/molmil-images/mine/3edl) | Kinesin13-Microtubule Ring complex | Descriptor: | 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, Beta tubulin, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Tan, D, Rice, W.J, Sosa, H. | Deposit date: | 2008-09-03 | Release date: | 2009-01-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (28 Å) | Cite: | Structure of the kinesin13-microtubule ring complex. Structure, 16, 2008
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3DCO
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![BU of 3dco by Molmil](/molmil-images/mine/3dco) | Drosophila NOD (3DC4) and Bovine Tubulin (1JFF) Docked into the 11-Angstrom Cryo-EM Map of Nucleotide-Free NOD Complexed to the Microtubule | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Bovine Alpha Tubulin, Bovine Beta Tubulin, ... | Authors: | Sindelar, C.V, Cochran, J.C, Kull, F.J. | Deposit date: | 2008-06-04 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.), 136, 2009
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4CK6
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![BU of 4ck6 by Molmil](/molmil-images/mine/4ck6) | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.AlFx state, based on cryo-electron microscopy experiment. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | Deposit date: | 2013-12-30 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CK7
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![BU of 4ck7 by Molmil](/molmil-images/mine/4ck7) | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx (NECK-LINKER IN ITS DISCONNECTED CONFORMATION, based on cryo-electron microscopy experiment | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | Deposit date: | 2013-12-30 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.2 Å) | Cite: | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CK5
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![BU of 4ck5 by Molmil](/molmil-images/mine/4ck5) | Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on cryo-electron microscopy experiment. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C. | Deposit date: | 2013-12-30 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family. Proc.Natl.Acad.Sci.USA, 111, 2014
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2WBE
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![BU of 2wbe by Molmil](/molmil-images/mine/2wbe) | Kinesin-5-Tubulin Complex with AMPPNP | Descriptor: | BIPOLAR KINESIN KRP-130, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Bodey, A.J, Kikkawa, M, Moores, C.A. | Deposit date: | 2009-02-26 | Release date: | 2009-03-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | 9-Angstrom Structure of a Microtubule-Bound Mitotic Motor. J.Mol.Biol., 388, 2009
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3J6H
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![BU of 3j6h by Molmil](/molmil-images/mine/3j6h) | Nucleotide-free Kinesin motor domain complexed with GMPCPP-microtubule | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin heavy chain isoform 5C, MAGNESIUM ION, ... | Authors: | Morikawa, M, Yajima, H, Nitta, R, Inoue, S, Ogura, T, Sato, C, Hirokawa, N. | Deposit date: | 2014-02-21 | Release date: | 2015-04-01 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding Embo J., 2015
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3J8X
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![BU of 3j8x by Molmil](/molmil-images/mine/3j8x) | High-resolution structure of no-nucleotide kinesin on microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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3J2U
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![BU of 3j2u by Molmil](/molmil-images/mine/3j2u) | Kinesin-13 KLP10A HD in complex with CS-tubulin and a microtubule | Descriptor: | Kinesin-like protein Klp10A, Tubulin alpha-1A chain, Tubulin beta-2B chain | Authors: | Asenjo, A.B, Chatterjee, C, Tan, D, DePaoli, V, Rice, W.J, Diaz-Avalos, R, Silvestry, M, Sosa, H. | Deposit date: | 2013-01-10 | Release date: | 2013-03-06 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (10.8 Å) | Cite: | Structural model for tubulin recognition and deformation by Kinesin-13 microtubule depolymerases. Cell Rep, 3, 2013
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3J8Y
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![BU of 3j8y by Molmil](/molmil-images/mine/3j8y) | High-resolution structure of ATP analog-bound kinesin on microtubules | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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5M5L
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![BU of 5m5l by Molmil](/molmil-images/mine/5m5l) | Pseudo-atomic model of microtubule-bound S. pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-21 | Release date: | 2016-11-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5MM4
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![BU of 5mm4 by Molmil](/molmil-images/mine/5mm4) | |
5M5I
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![BU of 5m5i by Molmil](/molmil-images/mine/5m5i) | Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus conformation allows formation of a cover neck bundle. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-21 | Release date: | 2016-11-30 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5O
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![BU of 5m5o by Molmil](/molmil-images/mine/5m5o) | Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-22 | Release date: | 2016-11-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M5M
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![BU of 5m5m by Molmil](/molmil-images/mine/5m5m) | Pseudo-atomic model of microtubule-bound S.pombe kinesin-5 motor domain in the AMPPNP state (based on cryo-electron microscopy experiment): the N-terminus adopts multiple conformations. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein cut7, ... | Authors: | Goulet, A, Moores, C.A, Cross, R.A. | Deposit date: | 2016-10-21 | Release date: | 2016-11-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Schizosaccharomyces pombe kinesin-5 switches direction using a steric blocking mechanism. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5ND2
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![BU of 5nd2 by Molmil](/molmil-images/mine/5nd2) | Microtubule-bound MKLP2 motor domain in the presence of ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | Deposit date: | 2017-03-07 | Release date: | 2017-10-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
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5ND4
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![BU of 5nd4 by Molmil](/molmil-images/mine/5nd4) | Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | Deposit date: | 2017-03-07 | Release date: | 2017-10-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
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5ND3
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![BU of 5nd3 by Molmil](/molmil-images/mine/5nd3) | Microtubule-bound MKLP2 motor domain in the with no nucleotide | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ... | Authors: | Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. | Deposit date: | 2017-03-07 | Release date: | 2017-10-04 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
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