2E88
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![BU of 2e88 by Molmil](/molmil-images/mine/2e88) | Crystal structure of the human Hsp70 ATPase domain in the apo form | Descriptor: | Heat shock 70kDa protein 1A, ZINC ION | Authors: | Shida, M, Ishii, R, Takagi, T, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-19 | Release date: | 2008-01-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state. Acta Crystallogr.,Sect.D, 66, 2010
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6KQP
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![BU of 6kqp by Molmil](/molmil-images/mine/6kqp) | NSD1 SET domain in complex with SAM | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, S-ADENOSYLMETHIONINE, ... | Authors: | Cho, H.J, Cierpicki, T. | Deposit date: | 2019-08-18 | Release date: | 2020-09-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Covalent inhibition of NSD1 histone methyltransferase. Nat.Chem.Biol., 16, 2020
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5MWW
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![BU of 5mww by Molmil](/molmil-images/mine/5mww) | Sigma1.1 domain of sigmaA from Bacillus subtilis | Descriptor: | RNA polymerase sigma factor SigA | Authors: | Zachrdla, M, Padrta, P, Rabatinova, A, Sanderova, H, Barvik, I, Krasny, L, Zidek, L. | Deposit date: | 2017-01-20 | Release date: | 2017-06-14 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Solution structure of domain 1.1 of the sigma (A) factor from Bacillus subtilis is preformed for binding to the RNA polymerase core. J. Biol. Chem., 292, 2017
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2C8P
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![BU of 2c8p by Molmil](/molmil-images/mine/2c8p) | lysozyme (60sec) and UV laser excited fluorescence | Descriptor: | LYSOZYME C | Authors: | Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. | Deposit date: | 2005-12-06 | Release date: | 2006-03-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
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6L1X
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![BU of 6l1x by Molmil](/molmil-images/mine/6l1x) | Quinol-dependent nitric oxide reductase (qNOR) from Neisseria meningitidis in the monomeric oxidized state with zinc complex. | Descriptor: | CALCIUM ION, FE (III) ION, Nitric-oxide reductase, ... | Authors: | Jamali, M.M.A, Antonyuk, S.V, Tosha, T, Muramoto, K, Hasnain, S.S, Shiro, Y. | Deposit date: | 2019-10-01 | Release date: | 2020-04-01 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The active form of quinol-dependent nitric oxide reductase fromNeisseria meningitidisis a dimer. Iucrj, 7, 2020
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2C8Q
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![BU of 2c8q by Molmil](/molmil-images/mine/2c8q) | insuline(1sec) and UV laser excited fluorescence | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. | Deposit date: | 2005-12-06 | Release date: | 2006-03-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
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8S9E
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![BU of 8s9e by Molmil](/molmil-images/mine/8s9e) | Solution structure of jarastatin (rJast), a disintegrin from Bothrops jararaca | Descriptor: | Disintegrin jarastatin | Authors: | Vasconcelos, A.A, Estrada, J.E.C, Zingali, R.B, Almeida, F.C.L. | Deposit date: | 2023-03-28 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Toward the mechanism of jarastatin (rJast) inhibition of the integrin alpha V beta 3. Int.J.Biol.Macromol., 255, 2024
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6H61
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![BU of 6h61 by Molmil](/molmil-images/mine/6h61) | CryoEM structure of the MDA5-dsRNA filament with 89 degree twist and without nucleotide | Descriptor: | Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), ... | Authors: | Yu, Q, Qu, K, Modis, Y. | Deposit date: | 2018-07-25 | Release date: | 2018-11-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.02 Å) | Cite: | Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Mol. Cell, 72, 2018
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8QNV
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6LXG
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![BU of 6lxg by Molmil](/molmil-images/mine/6lxg) | NMR solution structure of regulatory ACT domain of the Mycobacterium tuberculosis Rel protein | Descriptor: | GTP pyrophosphokinase | Authors: | Shin, J, Singal, B, Manimekalai, M.S.S, Gruber, G. | Deposit date: | 2020-02-11 | Release date: | 2020-11-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein. Febs J., 288, 2021
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6LKF
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6M3N
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![BU of 6m3n by Molmil](/molmil-images/mine/6m3n) | Solution structure of anti-CRISPR AcrIF7 | Descriptor: | anti-CRIPSR AcrIF7 | Authors: | Kim, I, An, S.Y, Koo, J, Bae, E, Suh, J.Y. | Deposit date: | 2020-03-04 | Release date: | 2020-08-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and mechanistic insights into the CRISPR inhibition of AcrIF7. Nucleic Acids Res., 48, 2020
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6M5C
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![BU of 6m5c by Molmil](/molmil-images/mine/6m5c) | Solution structure of avenatide aV1 | Descriptor: | avenatide aV1 | Authors: | Tay, S.V, Wong, K.H, Huang, J.Y, Fan, J.S, Yang, D.W, Tam, J.P. | Deposit date: | 2020-03-10 | Release date: | 2021-03-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure of avenatide aV1 To Be Published
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2FZ8
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![BU of 2fz8 by Molmil](/molmil-images/mine/2fz8) | Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking). | Descriptor: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | Authors: | Steuber, H, Zentgraf, M, Gerlach, C, Sotriffer, C.A, Heine, A, Klebe, G. | Deposit date: | 2006-02-09 | Release date: | 2006-10-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions. J.Mol.Biol., 363, 2006
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2FZB
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![BU of 2fzb by Molmil](/molmil-images/mine/2fzb) | Human Aldose Reductase complexed with four tolrestat molecules at 1.5 A resolution. | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT, aldose reductase | Authors: | Steuber, H, Zentgraf, M, Gerlach, C, Sotriffer, C.A, Heine, A, Klebe, G. | Deposit date: | 2006-02-09 | Release date: | 2006-10-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions. J.Mol.Biol., 363, 2006
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6GX5
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![BU of 6gx5 by Molmil](/molmil-images/mine/6gx5) | Narrow Pick Filament from Pick's disease brain | Descriptor: | Microtubule-associated protein tau | Authors: | Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2018-06-26 | Release date: | 2018-09-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of filaments from Pick's disease reveal a novel tau protein fold. Nature, 561, 2018
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6LUK
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2GA7
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![BU of 2ga7 by Molmil](/molmil-images/mine/2ga7) | Solution structure of the copper(I) form of the third metal-binding domain of ATP7A protein (menkes disease protein) | Descriptor: | COPPER (I) ION, Copper-transporting ATPase 1 | Authors: | Banci, L, Bertini, I, Cantini, F, DellaMalva, N, Rosato, A, Herrmann, T, Wuthrich, K, Structural Proteomics in Europe (SPINE) | Deposit date: | 2006-03-08 | Release date: | 2006-08-01 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure and intermolecular interactions of the third metal-binding domain of ATP7A, the Menkes disease protein. J.Biol.Chem., 281, 2006
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8S03
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![BU of 8s03 by Molmil](/molmil-images/mine/8s03) | NMR solution structure of the CysD2 domain of MUC2 | Descriptor: | CALCIUM ION, Mucin-2 | Authors: | Recktenwald, C, Karlsson, B.G, Garcia-Bonnete, M.-J, Katona, G, Jensen, M, Lymer, R, Baeckstroem, M, Johansson, M.E.V, Hansson, G.C, Trillo-Muyo, S. | Deposit date: | 2024-02-13 | Release date: | 2024-04-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking. Cell Rep, 43, 2024
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6LNZ
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6YW8
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8VSU
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![BU of 8vsu by Molmil](/molmil-images/mine/8vsu) | Cryo-EM structure of LKB1-STRADalpha-MO25alpha heterocomplex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Calcium-binding protein 39, Isoform 3 of STE20-related kinase adapter protein alpha, ... | Authors: | Chan, L.M, Courteau, B.J, Verba, K.A. | Deposit date: | 2024-01-24 | Release date: | 2024-07-10 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | High-resolution single-particle imaging at 100-200 keV with the Gatan Alpine direct electron detector. J.Struct.Biol., 216, 2024
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6C3P
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![BU of 6c3p by Molmil](/molmil-images/mine/6c3p) | Cryo-EM structure of human KATP bound to ATP and ADP in propeller form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Lee, K.P.K, Chen, J, MacKinnon, R. | Deposit date: | 2018-01-10 | Release date: | 2018-01-24 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Molecular structure of human KATP in complex with ATP and ADP. Elife, 6, 2017
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6BHN
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![BU of 6bhn by Molmil](/molmil-images/mine/6bhn) | Red Light-Absorbing State of NpR6012g4, a Red/Green Cyanobacteriochrome | Descriptor: | Methyl-accepting chemotaxis sensory transducer with phytochrome sensor, PHYCOCYANOBILIN | Authors: | Yu, Q, Lim, S, Rockwell, N.C, Martin, S.S, Lagarias, J.C, Ames, J.B. | Deposit date: | 2017-10-31 | Release date: | 2018-04-18 | Last modified: | 2019-12-04 | Method: | SOLUTION NMR | Cite: | Correlating structural and photochemical heterogeneity in cyanobacteriochrome NpR6012g4. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2FZ9
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![BU of 2fz9 by Molmil](/molmil-images/mine/2fz9) | Human Aldose Reductase complexed with inhibitor zopolrestat after six days soaking. | Descriptor: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | Authors: | Steuber, H, Zentgraf, M, Gerlach, C, Sotriffer, C.A, Heine, A, Klebe, G. | Deposit date: | 2006-02-09 | Release date: | 2006-10-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions. J.Mol.Biol., 363, 2006
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