PDB: 35712 resultsInfo pagesStatus searchChemie searchBIRD

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4XII	X-ray structure of human butyrylcholinesterase in complex with N-((1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl)methyl)-8-hydroxy-N-(2-methoxyethyl)-5-nitroquinoline-7-carboxamide Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Knez, D, Boris, B, Coquelle, N, Sosic, I, Sink, R, Brazzolotto, X, Mravljak, J, Colletier, J.P, Gobec, S. Deposit date: 2015-01-07 Release date: 2015-07-08 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents. Bioorg.Med.Chem., 23, 2015
1E6P	Chitinase B from Serratia marcescens inactive mutant E144Q Descriptor: CHITINASE B, GLYCEROL, SULFATE ION Authors: Komander, D, Synstad, B, Eijsink, V.G.H, Van Aalten, D.M.F. Deposit date: 2000-08-22 Release date: 2001-06-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Insights Into the Catalytic Mechanism of a Family 18 Exo-Chitinase Proc.Natl.Acad.Sci.USA, 98, 2001
4XIW	Carbonic anhydrase Cah3 from Chlamydomonas reinhardtii in complex with acetazolamide Descriptor: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase, alpha type, ... Authors: Hainzl, T, Grundstrom, C, Benlloch, R, Shevela, D, Shutova, T, Messinger, J, Samuelsson, G, Sauer-Eriksson, A.E. Deposit date: 2015-01-07 Release date: 2015-02-11 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii. Plant Physiol., 167, 2015
7D0W	Crystal structure of Hen Egg White Lysozyme Descriptor: CHLORIDE ION, Lysozyme C Authors: Iqbal, S, Krishnasamy, G. Deposit date: 2020-09-12 Release date: 2020-10-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of Hen Egg White Lysozyme To Be Published
4XET	Fe-Cl bound Y157F CDO at pH ~7.0 in the presence of azide Descriptor: CHLORIDE ION, Cysteine dioxygenase type 1, FE (III) ION Authors: Driggers, C.M, Karplus, P.A. Deposit date: 2014-12-24 Release date: 2016-04-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
3MUA	Enzyme-Substrate interactions of IXT6, the intracellular xylanase of G. stearothermophilus. Descriptor: ACETATE ION, GLYCEROL, SODIUM ION, ... Authors: Solomon, V, Zolotnitsky, G, Alhadeff, R, Shoham, Y, Shoham, G. Deposit date: 2010-05-02 Release date: 2011-06-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enzyme-Substrate interactions of IXT6, the intracellular xylanase of G. stearothermophilus. TO BE PUBLISHED
4XF0	cysteine dioxygenase variant - C93A at pH 8.0 with cysteine Descriptor: CHLORIDE ION, CYSTEINE, Cysteine dioxygenase type 1, ... Authors: Driggers, C.M, Karplus, P.A. Deposit date: 2014-12-25 Release date: 2016-03-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.3994 Å) Cite: Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
4XAG	Cycles of destabilization and repair underlie the evolution of new enzyme function Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R6, ... Authors: Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. Deposit date: 2014-12-14 Release date: 2015-12-16 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The role of protein dynamics in the evolution of new enzyme function. Nat.Chem.Biol., 12, 2016
3MV4	Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase Descriptor: BETA-MERCAPTOETHANOL, CARBONATE ION, FE (III) ION, ... Authors: Purpero, V.M, Lipscomb, J.D. Deposit date: 2010-05-03 Release date: 2011-06-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase To be Published
7DCP	cryo-EM structure of the DEAH-box helicase Prp2 and coactivator Spp2 Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PRP2 isoform 1, ... Authors: Bai, R, Wan, R, Yan, C, Jia, Q, Zhang, P, Lei, J, Shi, Y. Deposit date: 2020-10-26 Release date: 2021-01-06 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
4KM4	E. coli alkaline phosphatase mutant S102G/R166S in complex with inorganic phosphate Descriptor: Alkaline phosphatase, PHOSPHATE ION, ZINC ION Authors: Andrews, L.D, Fenn, T.D, Herschlag, D. Deposit date: 2013-05-08 Release date: 2013-07-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes. Plos Biol., 11, 2013
5HO2	Crystal structure of AbnA (open conformation), a GH43 extracellular arabinanase from Geobacillus stearothermophilus Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... Authors: Lansky, S, Shwartstien, O, Salama, R, Shoham, Y, Shoham, G. Deposit date: 2016-01-19 Release date: 2017-02-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Crystal structure of AbnA (open conformation), a GH43 extracellular arabinanase from Geobacillus stearothermophilus To Be Published
7DO7	Crystal structure of Azotobacter vinelandii L-rhamnose 1-dehydrogenase(NAD and L-rhamnose bound-form) Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Short-chain dehydrogenase/reductase SDR, beta-L-rhamnopyranose Authors: Yoshiwara, K, Watanabe, Y, Watanabe, S. Deposit date: 2020-12-12 Release date: 2021-02-03 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Crystal structure of l-rhamnose 1-dehydrogenase involved in the nonphosphorylative pathway of l-rhamnose metabolism in bacteria. Febs Lett., 595, 2021
4KRW	Novel re-arrangement of an RsmA/cSRa family protein to create a structurally distinct new RNA-binding family member Descriptor: IODIDE ION, RsmN, a RNA-binding protein of Regulator of Secondary Metabolism Authors: Li, C. Deposit date: 2013-05-17 Release date: 2013-09-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN. Structure, 21, 2013
5HQ1	Comment on S. W. M. Tanley and J. R. Helliwell Structural dynamics of cisplatin binding to histidine in a protein Struct. Dyn. 1, 034701 (2014) regarding the refinement of 4mwk, 4mwm, 4mwn and 4oxe and the method we have adopted. Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... Authors: Helliwell, J.R. Deposit date: 2016-01-21 Release date: 2016-05-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1 Å) Cite: Comment on "Structural dynamics of cisplatin binding to histidine in a protein" [Struct. Dyn. 1, 034701 (2014)]. Struct Dyn, 3, 2016
4XEN	High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... Authors: Yamada, H, Watanabe, N, Nagae, T. Deposit date: 2014-12-24 Release date: 2015-04-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
5HQE	Crystal structure of human dihydroorotate dehydrogenase (DHODH) with compound 18T Descriptor: ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... Authors: Huang, J, Wu, D, Lu, Q. Deposit date: 2016-01-21 Release date: 2016-07-27 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18T at 1.62 A resolution To Be Published
4XFG	cysteine dioxygenase variant - C93A at pH 6.2 with cysteine Descriptor: CHLORIDE ION, CYSTEINE, Cysteine dioxygenase type 1, ... Authors: Driggers, C.M, Karplus, P.A. Deposit date: 2014-12-26 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.401 Å) Cite: Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
5HV4	Crystal Structure of a Prolyl 4-Hydroxylase Complexed with Alpha-ketoglutarate from the Pathogenic Bacterium Bacillus anthracis in C2221 Descriptor: 2-OXOGLUTARIC ACID, 2OG-Fe(II) oxygenase, CADMIUM ION, ... Authors: Schnicker, N.J, Dey, M. Deposit date: 2016-01-28 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural analysis of cofactor binding for a prolyl 4-hydroxylase from the pathogenic bacterium Bacillus anthracis. Acta Crystallogr D Struct Biol, 72, 2016
4XF3	cysteine dioxygenase variant - Y157F at pH 8.0 with cysteine and dithionite Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION Authors: Driggers, C.M, Karplus, P.A. Deposit date: 2014-12-25 Release date: 2016-04-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
4XFC	cysteine dioxygenase variant - Y157F at pH 6.2 unliganded Descriptor: CHLORIDE ION, Cysteine dioxygenase type 1, FE (III) ION Authors: Driggers, C.M, Karplus, P.A. Deposit date: 2014-12-26 Release date: 2016-02-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.351 Å) Cite: Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
4KTJ	Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4-(3-amino-1H-pyrazol-4-yl)phenol Descriptor: 4-(3-amino-1H-pyrazol-4-yl)phenol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Hudson, S.A. Deposit date: 2013-05-20 Release date: 2013-07-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121. Chemmedchem, 8, 2013
4KTO	Crystal Structure Of a Putative Isovaleryl-CoA dehydrogenase (PSI-NYSGRC-012251) from Sinorhizobium meliloti 1021 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, isovaleryl-CoA dehydrogenase Authors: Kumar, P.R, Ahmed, M, Attonito, J, Bhosle, R, Bonanno, J, Chamala, S, Chowdhury, S, Glenn, A.S, Hammonds, J, Hillerich, B, Himmel, D, Love, J.D, Seidel, R, Stead, M, Toro, R, Wasserman, S.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2013-05-20 Release date: 2013-06-19 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.137 Å) Cite: Crystal structure of a Putative Isovaleryl-CoA dehydrogenase from Sinorhizobium meliloti 1021 to be published
1SDW	Reduced (Cu+) peptidylglycine alpha-hydroxylating monooxygenase with bound peptide and dioxygen Descriptor: COPPER (II) ION, GLYCEROL, N-ALPHA-ACETYL-3,5-DIIODOTYROSYL-D-THREONINE, ... Authors: Prigge, S.T, Eipper, B.A, Mains, R.E, Amzel, L.M. Deposit date: 2004-02-14 Release date: 2004-05-11 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex. Science, 304, 2004
4KR1	Crystal structure of the kinetechore protein Iml3 from budding yeast Descriptor: Central kinetochore subunit IML3 Authors: Tao, Y, Guo, Q, Teng, M. Deposit date: 2013-05-16 Release date: 2013-12-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural insights into the role of the Chl4-Iml3 complex in kinetochore assembly Acta Crystallogr.,Sect.D, 69, 2013

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