5HQE

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with compound 18T

Summary for 5HQE

• Entry DOI: 10.2210/pdb5hqe/pdb
• Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, methyl (2Z)-cyano[3-(2-fluoro-4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetate, FLAVIN MONONUCLEOTIDE, ... (7 entities in total)
• Functional Keywords: enzyme, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Mitochondrion inner membrane ; Single-pass membrane protein : Q02127
• Total number of polymer chains: 1
• Total formula weight: 44036.49

Authors

Huang, J.,Wu, D.,Lu, Q. (deposition date: 2016-01-21, release date: 2016-07-27, Last modification date: 2024-03-20)

• Primary citation: Huang, J.,Wu, D.,Lu, Q.; Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18T at 1.62 A resolution; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.62 Å)