4KTJ

Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4-(3-amino-1H-pyrazol-4-yl)phenol

Summary for 4KTJ

Entry DOI	10.2210/pdb4ktj/pdb
Related	4KTF 4KTK 4KTL
Descriptor	Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total)
Functional Keywords	p450, oxidoreductase, cyy, c-c bond formation, assumed cytosol
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	44158.47
Authors	Hudson, S.A. (deposition date: 2013-05-20, release date: 2013-07-03, Last modification date: 2023-09-20)
Primary citation	Hudson, S.A.,Surade, S.,Coyne, A.G.,McLean, K.J.,Leys, D.,Munro, A.W.,Abell, C. Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121. Chemmedchem, 8:1451-1456, 2013 Cited by PubMed: 23788280 DOI: 10.1002/cmdc.201300219 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation