PDB: 79225 resultsInfo pagesStatus searchChemie searchBIRD

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4G26	Crystal Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana with Ca Descriptor: CALCIUM ION, Pentatricopeptide repeat-containing protein At2g32230, mitochondrial, ... Authors: Koutmos, M, Howard, M.J, Fierke, C.A. Deposit date: 2012-07-11 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing. Proc.Natl.Acad.Sci.USA, 109, 2012
1MSY	GUAA tetraloop mutant of Sarcin/Ricin domain from E. Coli 23 S rRNA Descriptor: SARCIN/RICIN DOMAIN FROM 23 S RRNA Authors: Correll, C.C, Swinger, K. Deposit date: 2002-09-19 Release date: 2003-02-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Common and distinctive features of GNRA tetraloops based on a GUAA tetraloop structure at 1.4 A resolution RNA, 9, 2003
4G24	Crystal Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana with Mn Descriptor: 6-AMINOHEXANOIC ACID, MANGANESE (II) ION, Pentatricopeptide repeat-containing protein At2g32230, ... Authors: Koutmos, M, Howard, M.J, Fierke, C.A. Deposit date: 2012-07-11 Release date: 2012-09-26 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing. Proc.Natl.Acad.Sci.USA, 109, 2012
4YVI	Crystal Structure of H. influenzae TrmD in complex with sinefungin and tRNA Descriptor: SINEFUNGIN, tRNA, tRNA (guanine-N(1)-)-methyltransferase Authors: Yoshida, K, Ito, T, Yokoyama, S. Deposit date: 2015-03-20 Release date: 2015-07-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.01 Å) Cite: Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD. Proc.Natl.Acad.Sci.USA, 112, 2015
4YVJ	Crystal Structure of H. influenzae TrmD in complex with sinefungin and tRNA variant (G36U) Descriptor: SINEFUNGIN, tRNA, tRNA (guanine-N(1)-)-methyltransferase Authors: Yoshida, K, Ito, T, Yokoyama, S. Deposit date: 2015-03-20 Release date: 2015-07-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD. Proc.Natl.Acad.Sci.USA, 112, 2015
4YVK	Crystal Structure of H. influenzae TrmD in complex with sinefungin and tRNA variant (G36C) Descriptor: SINEFUNGIN, tRNA, tRNA (guanine-N(1)-)-methyltransferase Authors: Yoshida, K, Ito, T, Yokoyama, S. Deposit date: 2015-03-20 Release date: 2015-07-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.002 Å) Cite: Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD. Proc.Natl.Acad.Sci.USA, 112, 2015
3W3S	Crystal structure of A. aeolicus tRNASec in complex with M. kandleri SerRS Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, PLATINUM (II) ION, SULFATE ION, ... Authors: Itoh, Y, Sekine, S, Yokoyama, S. Deposit date: 2012-12-27 Release date: 2013-02-13 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.095 Å) Cite: Tertiary structure of bacterial selenocysteine tRNA Nucleic Acids Res., 41, 2013
8WF9	Cryo-EM structure of the PspCas13b-crRNA-target RNA complex (State 1) Descriptor: MAGNESIUM ION, PspCas13b, crRNA, ... Authors: Ishikawa, J, Kato, K, Yamashita, K, Nishizawa, T, Nishimasu, H. Deposit date: 2023-09-19 Release date: 2025-03-19 Last modified: 2025-06-18 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Structural insights into RNA-guided RNA editing by the Cas13b-ADAR2 complex. Nat.Struct.Mol.Biol., 2025
8WFA	Cryo-EM structure of the PspCas13b-crRNA-target RNA complex (State 2) Descriptor: MAGNESIUM ION, PspCas13b, crRNA, ... Authors: Ishikawa, J, Kato, K, Yamashita, K, Nishizawa, T, Nishimasu, H. Deposit date: 2023-09-19 Release date: 2025-03-19 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Structural insights into RNA-guided RNA editing by the Cas13b-ADAR2 complex. Nat.Struct.Mol.Biol., 2025
8WF8	Cryo-EM structure of the PspCas13b-crRNA complex Descriptor: MAGNESIUM ION, PspCas13b, crRNA Authors: Ishikawa, J, Kato, K, Yamashita, K, Nishizawa, T, Nishimasu, H. Deposit date: 2023-09-19 Release date: 2025-03-19 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (2.59 Å) Cite: Structural insights into RNA-guided RNA editing by the Cas13b-ADAR2 complex. Nat.Struct.Mol.Biol., 2025
7KJU	Cgi121-tRNA complex Descriptor: RNA (75-MER) Authors: Ceccarelli, D.F, Beenstock, J, Wan, L.C.K, Sicheri, F. Deposit date: 2020-10-26 Release date: 2020-12-02 Last modified: 2025-06-25 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A substrate binding model for the KEOPS tRNA modifying complex. Nat Commun, 11, 2020
7OVO	Heterodimeric murine tRNA-guanine transglycosylase in complex with queuine Descriptor: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Queuine tRNA-ribosyltransferase accessory subunit 2, ... Authors: Sebastiani, M, Heine, A, Reuter, K. Deposit date: 2021-06-15 Release date: 2022-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022
7OV9	Heterodimeric tRNA-Guanine Transglycosylase from mouse, apo-structure Descriptor: HEXAETHYLENE GLYCOL, Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ... Authors: Sebastiani, M, Heine, A, Reuter, K. Deposit date: 2021-06-14 Release date: 2022-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase. Acs Chem.Biol., 17, 2022
2GIA	Crystal structures of trypanosoma bruciei MRP1/MRP2 Descriptor: ACETIC ACID, mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2 Authors: Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J. Deposit date: 2006-03-28 Release date: 2006-09-05 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism. Cell(Cambridge,Mass.), 126, 2006
2GID	Crystal structures of trypanosoma bruciei MRP1/MRP2 Descriptor: mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2 Authors: Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J. Deposit date: 2006-03-28 Release date: 2006-09-05 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism. Cell(Cambridge,Mass.), 126, 2006
1EXD	CRYSTAL STRUCTURE OF A TIGHT-BINDING GLUTAMINE TRNA BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE TRNA APTAMER, GLUTAMINYL-TRNA SYNTHETASE, ... Authors: Bullock, T.L, Sherlin, L.D, Perona, J.J. Deposit date: 2000-05-02 Release date: 2000-05-15 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Tertiary core rearrangements in a tight binding transfer RNA aptamer. Nat.Struct.Biol., 7, 2000
4WZQ	Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA Descriptor: MANGANESE (II) ION, RNA dependent-RNA polymerase 3D, RNA template, ... Authors: Verdaguer, N, Ferrer-Orta, C. Deposit date: 2014-11-20 Release date: 2015-05-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
7NIQ	CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(Major class) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ... Authors: Yu, Q, Modis, Y. Deposit date: 2021-02-13 Release date: 2021-11-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
7NIC	CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ADP-AlF4(minor class) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), ... Authors: Yu, Q, Modis, Y. Deposit date: 2021-02-11 Release date: 2021-11-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
7NGA	CryoEM structure of the MDA5-dsRNA filament in complex with ADP with 88-degree helical twist Descriptor: ADENOSINE-5'-DIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*AP*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*G)-3'), ... Authors: Yu, Q, Modis, Y. Deposit date: 2021-02-08 Release date: 2021-11-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
124D	STRUCTURE OF A DNA:RNA HYBRID DUPLEX: WHY RNASE H DOES NOT CLEAVE PURE RNA Descriptor: DNA (5'-D(*GP*TP*CP*AP*CP*AP*TP*G)-3'), RNA (5'-R(*CP*AP*UP*GP*UP*GP*AP*C)-3') Authors: Fedoroff, O.Y, Salazar, M, Reid, B.R. Deposit date: 1993-05-07 Release date: 1993-10-31 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of a DNA:RNA Hybrid Duplex. Why Rnase H Does not Cleave Pure RNA J.Mol.Biol., 233, 1993
8GS2	Structure of the Cas7-11-Csx29-guide RNA-target RNA (non-matching PFS) complex Descriptor: ADENOSINE MONOPHOSPHATE, CHAT domain-containing protein, CRISPR-associated RAMP family protein, ... Authors: Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. Deposit date: 2022-09-04 Release date: 2022-11-09 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.84 Å) Cite: RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
4TRA	RESTRAINED REFINEMENT OF TWO CRYSTALLINE FORMS OF YEAST ASPARTIC ACID AND PHENYLALANINE TRANSFER RNA CRYSTALS Descriptor: MAGNESIUM ION, TRNAPHE Authors: Westhof, E, Dumas, P, Moras, D. Deposit date: 1987-11-06 Release date: 1987-11-06 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals. Acta Crystallogr.,Sect.A, 44, 1988
8KAJ	Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 16nt target DNA Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*TP*TP*TP*AP*TP*CP*CP*AP*TP*AP*AP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ... Authors: Chen, Y, Chen, J, Liu, L. Deposit date: 2023-08-03 Release date: 2024-06-05 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (3.42 Å) Cite: Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 43, 2025
8KAH	Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 18nt target DNA Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ... Authors: Chen, Y, Chen, J, Liu, L. Deposit date: 2023-08-03 Release date: 2024-06-05 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (3.36 Å) Cite: Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 43, 2025

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