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4Q93
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BU of 4q93 by Molmil
Crystal structure of resveratrol bound human tyrosyl tRNA synthetase
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Mathew, S, Schimmel, P.
Deposit date:2014-04-28
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Nature, 519, 2014
6UP0
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BU of 6up0 by Molmil
Structure of the Mango-III fluorescent aptamer bound to YO3-Biotin
Descriptor: MAGNESIUM ION, Mango-III fluorescent aptamer, POTASSIUM ION, ...
Authors:Trachman, R.J, Ferre-D'Amare, A.R.
Deposit date:2019-10-16
Release date:2020-10-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET.
Rna, 27, 2021
4R8I
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BU of 4r8i by Molmil
High Resolution Structure of a Mirror-Image RNA Oligonucleotide Aptamer in Complex with the Chemokine CCL2
Descriptor: C-C motif chemokine 2, Mirror-Image RNA Oligonucleotide Aptamer NOXE36, POTASSIUM ION, ...
Authors:Oberthuer, D, Achenbach, J, Gabdulkhakov, A, Falke, S, Buchner, K, Maasch, C, Rehders, D, Klussmann, S, Betzel, C.
Deposit date:2014-09-02
Release date:2015-04-29
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.
Nat Commun, 6, 2015
2VAZ
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BU of 2vaz by Molmil
Model of the S15-mRNA complex fitted into the cryo-EM map of the 70S entrapment complex.
Descriptor: 30S RIBOSOMAL PROTEIN S15, RPSO MRNA OPERATOR
Authors:Marzi, S, Myasnikov, A.G, Serganov, A, Ehresmann, C, Romby, P, Yusupov, M, Klaholz, B.P.
Deposit date:2007-09-05
Release date:2007-10-02
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structured Mrnas Regulate Translation Initiation by Binding to the Platform of the Ribosome.
Cell(Cambridge,Mass.), 130, 2007
4QBT
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BU of 4qbt by Molmil
Crystal structure of tyrosine bound human tyrosyl tRNA synthetase
Descriptor: GLYCEROL, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Mathew, S, Schimmel, P.
Deposit date:2014-05-08
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Nature, 519, 2014
3AY0
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BU of 3ay0 by Molmil
Crystal structure of Methanocaldococcus jannaschii Trm5 in complex with adenosine
Descriptor: ADENOSINE, Uncharacterized protein MJ0883, ZINC ION
Authors:Goto-Ito, S, Ito, T, Hou, Y.M, Yokoyama, S.
Deposit date:2011-04-21
Release date:2011-08-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
Rna, 17, 2011
7BKP
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BU of 7bkp by Molmil
CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ...
Authors:Singh, R, Herrero del Valle, A, Yu, Q, Modis, Y.
Deposit date:2021-01-16
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
1T6N
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BU of 1t6n by Molmil
Crystal structure of the N-terminal domain of human UAP56
Descriptor: CITRATE ANION, Probable ATP-dependent RNA helicase
Authors:Zhao, R.
Deposit date:2004-05-06
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal Structure of UAP56, a DExD/H-Box Protein Involved in Pre-mRNA Splicing and mRNA Export
Structure, 12, 2004
7BKQ
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BU of 7bkq by Molmil
CryoEM structure of MDA5-dsRNA filament in complex with ADP with 92-degree helical twist
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Isoform 2 of Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
Authors:Yu, Q, Modis, Y.
Deposit date:2021-01-17
Release date:2021-11-17
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA.
Nat Commun, 12, 2021
2GXB
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BU of 2gxb by Molmil
Crystal Structure of The Za Domain bound to Z-RNA
Descriptor: 5'-R(P*(DU)P*CP*GP*CP*GP*CP*G)-3', Double-stranded RNA-specific adenosine deaminase, SODIUM ION
Authors:Athanasiadis, A, Placido, D, Rich, A.
Deposit date:2006-05-08
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A Left-Handed RNA Double Helix Bound by the Zalpha Domain of the RNA-Editing Enzyme ADAR1.
Structure, 15, 2007
1M5L
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BU of 1m5l by Molmil
Structure of wild-type and mutant internal loops from the SL-1 domain of the HIV-1 packaging signal
Descriptor: modified HIV-1 packaging signal stem-loop 1 RNA
Authors:Gallego, J, Greatorex, J, Varani, G, Lever, A.
Deposit date:2002-07-09
Release date:2002-09-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and stability of wild-type and mutant RNA internal loops from the SL-1 domain of the HIV-1 packaging signal
J.Mol.Biol., 322, 2002
7BY6
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BU of 7by6 by Molmil
Plasmodium vivax cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD1389
Descriptor: (3S,4R,8R,9R,10S)-N-(4-cyclopropyloxyphenyl)-10-(methoxymethyl)-3,4-bis(oxidanyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanyl-tRNA synthetase beta chain, ...
Authors:Malhotra, N, Manmohan, S, Harlos, K, Melillo, B, Schreiber, S.L, Manickam, Y, Sharma, S.
Deposit date:2020-04-21
Release date:2020-11-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines.
Nat Commun, 12, 2021
4ILH
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BU of 4ilh by Molmil
Crystal structure of an Aar2p C-terminal deletion mutant in conplex with Prp8p RNaseH
Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
Authors:Weber, G, Heroven, A.C, Santos, K.F, Wahl, M.C.
Deposit date:2012-12-31
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for the Aar2p-mediated regulation of Prp8p interactions with Brr2p and U4/U6 di-snRNA
To be Published
2LBR
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BU of 2lbr by Molmil
Conformation Effects of Base Modification on the Anticodon Stem-loop of Bacillus subtilis tRNATYR
Descriptor: RNA (5'-R(*GP*GP*GP*GP*AP*CP*UP*GP*UP*AP*(6IA)P*AP*(PSU)P*CP*CP*CP*C)-3')
Authors:Denmon, A.P, Wang, J, Nikonowicz, E.P.
Deposit date:2011-04-05
Release date:2011-08-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformation Effects of Base Modification on the Anticodon Stem-Loop of Bacillus subtilis tRNA(Tyr).
J.Mol.Biol., 412, 2011
3C46
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BU of 3c46 by Molmil
X-ray crystal structure of the N4 mini-vRNAP P2_7a promoter complex soaked with MgCl2
Descriptor: DIHYDROGENPHOSPHATE ION, P2_7a Promoter DNA, Virion RNA polymerase
Authors:Gleghorn, M.L, Murakami, K.S.
Deposit date:2008-01-29
Release date:2008-12-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase.
Mol.Cell, 32, 2008
3C2P
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BU of 3c2p by Molmil
X-ray crystal structure of the N4 mini-vRNAP P1 promoter complex
Descriptor: P1 Promoter DNA, Virion RNA polymerase
Authors:Gleghorn, M.L, Murakami, K.S.
Deposit date:2008-01-25
Release date:2008-12-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase.
Mol.Cell, 32, 2008
3C3L
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BU of 3c3l by Molmil
X-ray crystal structure of the N4 mini-vRNAP P2 promoter complex
Descriptor: P2 Promoter DNA, Virion RNA polymerase
Authors:Gleghorn, M.L, Murakami, K.S.
Deposit date:2008-01-28
Release date:2008-12-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase.
Mol.Cell, 32, 2008
4NOY
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BU of 4noy by Molmil
Crystal structure of Listeria monocytogenes Hfq F43W
Descriptor: Protein Hfq, S-1,2-PROPANEDIOL
Authors:Canty, J.T, Kovach, A.R, Brennan, R.G.
Deposit date:2013-11-20
Release date:2014-09-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.
Rna, 20, 2014
4NL2
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BU of 4nl2 by Molmil
Crystal Structure of Listeria monocytogenes Hfq
Descriptor: Protein hfq, S-1,2-PROPANEDIOL
Authors:Kovach, A.R, Brennan, R.G.
Deposit date:2013-11-13
Release date:2014-09-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.
Rna, 20, 2014
1SLO
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BU of 1slo by Molmil
FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3')
Authors:Greenbaum, N.L, Radhakrishnan, I, Patel, D.J, Hirsh, D.
Deposit date:1996-05-24
Release date:1996-12-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the donor site of a trans-splicing RNA.
Structure, 4, 1996
1SLP
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BU of 1slp by Molmil
FIRST STEM LOOP OF THE SL1 RNA FROM CAENORHABDITIS ELEGANS, NMR, 16 STRUCTURES
Descriptor: RNA (5'-R(*UP*UP*AP*CP*CP*CP*AP*AP*GP*UP*UP*UP*GP*AP*GP*GP*UP*AP*A)-3')
Authors:Greenbaum, N.L, Radhakrishnan, I, Patel, D.J, Hirsh, D.
Deposit date:1996-05-24
Release date:1997-04-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the donor site of a trans-splicing RNA.
Structure, 4, 1996
2LO6
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BU of 2lo6 by Molmil
Structure of Nrd1 CID bound to phosphorylated RNAP II CTD
Descriptor: DNA-directed RNA polymerase II subunit RPB1, Protein NRD1
Authors:Kubicek, K, Cerna, H, Pasulka, J, Holub, P, Hrossova, D, Loehr, F, Hofr, C, Vanacova, S, Stefl, R.
Deposit date:2012-01-17
Release date:2012-12-26
Method:SOLUTION NMR
Cite:Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1.
Genes Dev., 26, 2012
1TN2
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BU of 1tn2 by Molmil
CRYSTALLOGRAPHIC AND BIOCHEMICAL INVESTIGATION OF THE LEAD(II)-CATALYZED HYDROLYSIS OF YEAST PHENYLALANINE T-RNA
Descriptor: LEAD (II) ION, MAGNESIUM ION, SPERMINE, ...
Authors:Brown, R.S, Dewan, J.C, Klug, A.
Deposit date:1986-08-22
Release date:1986-10-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA.
Biochemistry, 24, 1985
3WZI
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BU of 3wzi by Molmil
Crystal structure of AfCsx3 in complex with ssRNA
Descriptor: Uncharacterized protein AF_1864, ssRNA
Authors:Yuan, Y.A, Yan, X.
Deposit date:2014-09-25
Release date:2015-07-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of CRISPR-associated Csx3 reveal a manganese-dependent deadenylation exoribonuclease.
Rna Biol., 12, 2015
3ZXI
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BU of 3zxi by Molmil
Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with a tyrosyl-adenylate analog
Descriptor: PHOSPHORIC ACID 2-AMINO-3-(4-HYDROXY-PHENYL)-PROPYL ESTER ADENOSIN-5'YL ESTER, TYROSYL-TRNA SYNTHETASE, MITOCHONDRIAL
Authors:Bonnefond, L, Frugier, M, Rudinger-Thirion, J, Balg, C, Chenevert, R, Lorber, B, Giege, R, Sauter, C.
Deposit date:2011-08-11
Release date:2011-11-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Exploiting Protein Engineering and Crystal Polymorphism for Successful X-Ray Structure Determination
Cryst.Growth Des., 11, 2011

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