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4V72
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BU of 4v72 by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre4)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
Deposit date:2013-10-14
Release date:2014-07-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
8B3Z
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BU of 8b3z by Molmil
SigE N-terminal Domain
Descriptor: RNA polymerase sigma factor
Authors:Evans, N.J, Isaacson, R.L, Collins, K.M, Camp, A.H.
Deposit date:2022-09-18
Release date:2023-08-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Analysis of Bacillus subtilis Sigma Factors.
Microorganisms, 11, 2023
4FO0
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BU of 4fo0 by Molmil
Human actin-related protein Arp8 in its ATP-bound state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 8, CHLORIDE ION, ...
Authors:Gerhold, C.B, Lakomek, K, Seifert, F.U, Hopfner, K.-P.
Deposit date:2012-06-20
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Actin-related protein 8 and its contribution to nucleosome binding.
Nucleic Acids Res., 40, 2012
4V4W
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BU of 4v4w by Molmil
Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
Authors:Mitra, K, Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
4V4V
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BU of 4v4v by Molmil
Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
Authors:Mitra, K, Frank, J.
Deposit date:2006-05-09
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
2FXA
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BU of 2fxa by Molmil
Structure of the Protease Production Regulatory Protein hpr from Bacillus subtilis.
Descriptor: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, PENTAETHYLENE GLYCOL, ...
Authors:Cuff, M.E, Skarina, T, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-02-03
Release date:2006-03-14
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Protease Production Regulatory Protein hpr from Bacillus subtilis.
TO BE PUBLISHED
4W4U
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BU of 4w4u by Molmil
Structure of yeast SAGA DUBm with Sgf73 Y57A mutant at 2.8 angstroms resolution
Descriptor: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ...
Authors:Wolberger, C, Yan, M.
Deposit date:2014-08-15
Release date:2015-07-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.
J.Mol.Biol., 427, 2015
4W5R
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BU of 4w5r by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8 (Long Target)
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5Q
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BU of 4w5q by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
8GCR
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BU of 8gcr by Molmil
HPV16 E6-E6AP-p53 complex
Descriptor: Cellular tumor antigen p53, Maltose/maltodextrin-binding periplasmic protein,Protein E6, Ubiquitin-protein ligase E3A, ...
Authors:Bratkowski, M.A, Wang, J.C.K, Hao, Q, Nile, A.H.
Deposit date:2023-03-02
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structure of the p53 degradation complex from HPV16.
Nat Commun, 15, 2024
8BVH
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BU of 8bvh by Molmil
Cryo-EM structure of the Hfq-Crc-amiE translation repression assembly.
Descriptor: Catabolite repression control protein, RNA-binding protein Hfq, amiE
Authors:Dendooven, T, Luisi, B.F.
Deposit date:2022-12-03
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding.
Embo J., 42, 2023
8B5L
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BU of 8b5l by Molmil
Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K.
Deposit date:2022-09-23
Release date:2023-03-01
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.
Sci Adv, 9, 2023
8B6C
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BU of 8b6c by Molmil
Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147
Descriptor: 28S rRNA, 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{N},~{N}-dimethyl-aniline, 5.8S rRNA, ...
Authors:Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K.
Deposit date:2022-09-26
Release date:2023-02-22
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.
Sci Adv, 9, 2023
6WMZ
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BU of 6wmz by Molmil
Crystal structure of human SFPQ/NONO complex
Descriptor: Non-POU domain-containing octamer-binding protein, SULFATE ION, Splicing factor, ...
Authors:Lee, M, Bond, C.S.
Deposit date:2020-04-22
Release date:2021-04-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure analysis of human SFPQ/NONO complex
To Be Published
4V2F
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BU of 4v2f by Molmil
Tetracycline repressor TetR(D), unliganded
Descriptor: TETRACYCLINE REPRESSOR PROTEIN CLASS D
Authors:Werten, S, Orth, P, Saenger, W, Hinrichs, W.
Deposit date:2014-10-09
Release date:2014-12-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition.
Biochemistry, 53, 2014
4V2G
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BU of 4v2g by Molmil
Tetracycline repressor TetR(D) bound to chlortetracycline and iso- chlortetracycline
Descriptor: 7-CHLOROTETRACYCLINE, ISO-7-CHLORTETRACYCLINE, MAGNESIUM ION, ...
Authors:Werten, S, Orth, P, Saenger, W, Hinrichs, W.
Deposit date:2014-10-09
Release date:2014-12-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition.
Biochemistry, 53, 2014
1W5W
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BU of 1w5w by Molmil
HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor
Descriptor: (2R,3R,4R,5R)-2,5-BIS[(2,4-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1R,2S)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXAN EDIAMIDE, POL POLYPROTEIN
Authors:Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T.
Deposit date:2004-08-10
Release date:2004-12-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
4UY8
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BU of 4uy8 by Molmil
Molecular basis for the ribosome functioning as a L-tryptophan sensor - Cryo-EM structure of a TnaC stalled E.coli ribosome
Descriptor: 50S RIBOSOMAL PROTEIN L10, 50S RIBOSOMAL PROTEIN L11, 50S RIBOSOMAL PROTEIN L13, ...
Authors:Bischoff, L, Berninghausen, O, Beckmann, R.
Deposit date:2014-08-29
Release date:2014-10-29
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular Basis for the Ribosome Functioning as an L-Tryptophan Sensor.
Cell Rep., 9, 2014
2XYI
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BU of 2xyi by Molmil
Crystal Structure of Nurf55 in complex with a H4 peptide
Descriptor: DI(HYDROXYETHYL)ETHER, HISTONE H4, PROBABLE HISTONE-BINDING PROTEIN CAF1, ...
Authors:Stirnimann, C.U, Nowak, A.J, Mueller, C.W.
Deposit date:2010-11-17
Release date:2011-05-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Chromatin-Modifying Complex Component Nurf55/P55 Associates with Histones H3, H4 and Polycomb Repressive Complex 2 Subunit Su(Z)12 Through Partially Overlapping Binding Sites.
J.Biol.Chem., 286, 2011
3KYC
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BU of 3kyc by Molmil
Human SUMO E1 complex with a SUMO1-AMP mimic
Descriptor: 5'-deoxy-5'-(sulfamoylamino)adenosine, SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ...
Authors:Lima, C.D.
Deposit date:2009-12-05
Release date:2010-02-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
7CBV
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BU of 7cbv by Molmil
Crystal structure of the transcriptional regulator PadR from Bacillus subtilis (space group H32)
Descriptor: PadR family transcriptional regulator
Authors:Park, S.C, Song, W.S, Yoon, S.I.
Deposit date:2020-06-14
Release date:2021-04-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Apo structure of the transcriptional regulator PadR from Bacillus subtilis: Structural dynamics and conserved Y70 residue.
Biochem.Biophys.Res.Commun., 530, 2020
3KYD
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BU of 3kyd by Molmil
Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic
Descriptor: 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ...
Authors:Lima, C.D.
Deposit date:2009-12-05
Release date:2010-02-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
7MQ3
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BU of 7mq3 by Molmil
C9A N55A Streptococcus pneumoniae CstR in the reduced state
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Copper-sensing transcriptional repressor csoR, SODIUM ION
Authors:Fakhoury, J, Gonzalez-Gutierrez, G, Giedroc, D.P.
Deposit date:2021-05-05
Release date:2022-03-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Functional asymmetry and chemical reactivity of CsoR family persulfide sensors.
Nucleic Acids Res., 49, 2021
5W3X
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BU of 5w3x by Molmil
Crystal structure of PopP2 in complex with IP6, AcCoA and the WRKY domain of RRS1-R .
Descriptor: ACETYL COENZYME *A, Disease resistance protein RRS1, GLYCEROL, ...
Authors:Zhang, Z.M, Gao, L, Song, J.
Deposit date:2017-06-08
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of host substrate acetylation by a YopJ family effector.
Nat Plants, 3, 2017
5VHS
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BU of 5vhs by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2017-04-13
Release date:2017-08-23
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017

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