4V2G

Tetracycline repressor TetR(D) bound to chlortetracycline and iso- chlortetracycline

Replaces:  1BJY

Summary for 4V2G

• Entry DOI: 10.2210/pdb4v2g/pdb
• Related: 4V2F
• Descriptor: TETRACYCLINE REPRESSOR PROTEIN CLASS D, ISO-7-CHLORTETRACYCLINE, 7-CHLOROTETRACYCLINE, ... (5 entities in total)
• Functional Keywords: transcription, repressor, antibiotic resistance, tetr
• Biological source: ESCHERICHIA COLI
• Total number of polymer chains: 2
• Total formula weight: 47558.73

Authors

Werten, S.,Orth, P.,Saenger, W.,Hinrichs, W. (deposition date: 2014-10-09, release date: 2014-12-10, Last modification date: 2024-01-10)

• Primary citation: Werten, S.,Dalm, D.,Palm, G.J.,Grimm, C.C.,Hinrichs, W.; Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition.; Biochemistry, 53:7990-, 2014; PubMed: 25432019; DOI: 10.1021/BI5012805

Experimental method

X-RAY DIFFRACTION (2.71 Å)