PDB: 222624 resultsInfo pagesStatus searchChemie searchBIRD

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8VN5	Homing endonuclease I-PpoI-DNA complex:ground state at pH8.0 (Tris) with Na+ Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VN4	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 1200s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), DNA (5'-D(P*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VN3	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 600s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), DNA (5'-D(P*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VN2	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 320s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VN1	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 160s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VN0	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 80s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMZ	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 40s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMY	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 20s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMX	Homing endonuclease I-PpoI-DNA complex:reaction at pH6.0 (K+ MES) with 500 uM Mg2+ for 10s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMW	Homing endonuclease I-PpoI-DNA complex:ground state at pH6.0 (K+ MES) with Na+ Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMV	Homing endonuclease I-PpoI-DNA complex:reaction at pH7.0 (K+ MES) with 500 uM Mg2+ for 600s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), DNA (5'-D(P*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMU	Homing endonuclease I-PpoI-DNA complex:reaction at pH7.0 (K+ MES) with 500 uM Mg2+ for 320s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMT	Homing endonuclease I-PpoI-DNA complex:reaction at pH7.0 (K+ MES) with 500 uM Mg2+ for 160s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMS	Homing endonuclease I-PpoI-DNA complex:reaction at pH7.0 (K+ MES) with 500 uM Mg2+ for 80s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMR	Homing endonuclease I-PpoI-DNA complex:reaction at pH7.0 (K+ MES) with 500 uM Mg2+ for 40s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMQ	Homing endonuclease I-PpoI-DNA complex:reaction at pH7.0 (K+ MES) with 500 uM Mg2+ for 20s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMP	Homing endonuclease I-PpoI-DNA complex:reaction at pH7.0 (K+ MES) with 500 uM Mg2+ for 10s Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VMO	Homing endonuclease I-PpoI-DNA complex:ground state at pH7.0 (K+ MES) with Na+ Descriptor: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), GLYCEROL, Intron-encoded endonuclease I-PpoI, ... Authors: Chang, C, Gao, Y. Deposit date: 2024-01-13 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Homing endonuclease I-PpoI-DNA complex:reaction with 500 uM Mg2+ for 160s To Be Published
8VM2	Crystal Structure of NRAS Q61K bound to GTP Descriptor: GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Gebregiworgis, T, Chan, J.Y.L, Kuntz, D.A, Prive, G.G, Marshall, C.B, Ikura, M. Deposit date: 2024-01-12 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II. Eur J Cell Biol, 103, 2024
8VLY	Cryo-EM structure of human HGSNAT in transition state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heparan-alpha-glucosaminide N-acetyltransferase Authors: Li, F, Zhao, B. Deposit date: 2024-01-12 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome To Be Published
8VLX	HTT in complex with HAP40 and a small molecule. Descriptor: 40-kDa huntingtin-associated protein, Huntingtin, N-[(1S,2R)-2-benzylcyclopentyl]-N'-{1-[(1S)-1-(pyridin-4-yl)ethyl]piperidin-4-yl}urea Authors: Poweleit, N, Boudet, J, Doherty, E. Deposit date: 2024-01-12 Release date: 2024-03-06 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Discovery of a Small Molecule Ligand to the Huntingtin/HAP40 complex To Be Published
8VLV	Cryo-EM structure of human HGSNAT in inactive state Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heparan-alpha-glucosaminide N-acetyltransferase Authors: Li, F. Deposit date: 2024-01-12 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome To Be Published
8VLU	Cryo-EM structure of human HGSNAT bound with CoA Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, Heparan-alpha-glucosaminide N-acetyltransferase Authors: Li, F, Zhao, B. Deposit date: 2024-01-12 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome To Be Published
8VLS	Structure of VCP in complex with an ATPase activator (D2 domains only, dodecameric form) Descriptor: (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, Transitional endoplasmic reticulum ATPase Authors: Jones, N.H, Urnivicius, L, Kapoor, T.M. Deposit date: 2024-01-12 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry. Proc.Natl.Acad.Sci.USA, 121, 2024
8VLQ	Structure of PmHMGR bound to mevalonate, CoA and NAD 5 minutes after reaction initiation at pH 9 Descriptor: (R)-MEVALONATE, (R)-mevaldehyde, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Purohit, V, Steussy, C.N, Stauffacher, C.V. Deposit date: 2024-01-12 Release date: 2024-03-20 Method: X-RAY DIFFRACTION (2.07 Å) Cite: pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography. Biophys.J., 123, 2024

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