PDB: 52994 resultsInfo pagesStatus searchChemie searchBIRD

---

7TSQ	Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, AMP state Descriptor: ADENOSINE MONOPHOSPHATE, Cap2, Cyclic AMP-AMP-GMP synthase, ... Authors: Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. Deposit date: 2022-01-31 Release date: 2023-01-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.11 Å) Cite: An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
8U2U	Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (CoA, AMP and potassium bound) Descriptor: ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-09-06 Release date: 2023-09-13 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (CoA, AMP and potassium bound) To be published
4O22	Binary complex of metal-free PKAc with SP20. Descriptor: Phosphorylated peptide pSP20., cAMP-dependent protein kinase catalytic subunit alpha. Authors: Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S.S. Deposit date: 2013-12-16 Release date: 2014-05-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
4O21	Product complex of metal-free PKAc, ATP-gamma-S and SP20. Descriptor: ADENOSINE-5'-DIPHOSPHATE, Thio-phosphorylated peptide pSP20, cAMP-dependent protein kinase catalytic subunit alpha Authors: Das, A, Kovalevsky, A.Y, Gerlits, O, Langan, P, Heller, W.T, Keshwani, M, Taylor, S. Deposit date: 2013-12-16 Release date: 2014-05-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014
8EFM	Structure of coral STING receptor from Stylophora pistillata in complex with 2',3'-cGAMP Descriptor: SULFATE ION, Stimulator of interferon genes protein, cGAMP Authors: Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. Deposit date: 2022-09-08 Release date: 2023-07-05 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.13 Å) Cite: cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
8U2T	Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (CoA and AMP bound) Descriptor: ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-09-06 Release date: 2023-09-13 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (CoA and AMP bound) To be published
8T5N	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound) Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-06-14 Release date: 2023-06-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound) To be published
6S27	Crystal structure of human wild type STING in complex with 2'3'-cyclic-GMP-2'F-2'dAMP Descriptor: 2'3'-cyclic-GMP-2'F-2'dAMP, Stimulator of interferon protein Authors: Smola, M, Boura, E. Deposit date: 2019-06-20 Release date: 2019-11-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.802 Å) Cite: Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. J.Med.Chem., 62, 2019
8V4O	Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP from Candida albicans Descriptor: ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-11-29 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP from Candida albicans To be published
6BLJ	Crystal structure of cytoplasmic Serine-tRNA ligase from Naegleria fowleri in complex with AMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Serine-tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2017-11-10 Release date: 2017-12-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of cytoplasmic Serine-tRNA ligase from Neisseria fowlerii in complex with AMP TO BE PUBLISHED
6M2T	The crystal structure of benzoate coenzyme A ligase double mutant (H333A/I334A) in complex with 2-methyl-thiazole-5 carboxylate-AMP Descriptor: 2-methyl-1,3-thiazole-5-carboxylic acid, ADENOSINE MONOPHOSPHATE, Benzoate-coenzyme A ligase Authors: Li, T.L, Adhikari, K. Deposit date: 2020-02-29 Release date: 2021-03-03 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.14 Å) Cite: The crystal structure of benzoate coenzyme A ligase double mutant (H333A/I334A) in complex with 2-methyl-thiazole-5 carboxylate-AMP To Be Published
8V4R	Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP and CoA from Candida albicans Descriptor: ACETIC ACID, ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase 2, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-11-29 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP and CoA from Candida albicans To be published
7T29	Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-03 Release date: 2021-12-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP to be published
1RGK	RNASE T1 MUTANT GLU46GLN BINDS THE INHIBITORS 2'GMP AND 2'AMP AT THE 3' SUBSITE Descriptor: ADENOSINE-2'-MONOPHOSPHATE, CALCIUM ION, RIBONUCLEASE T1 Authors: Granzin, J, Puras-Lutzke, R, Landt, O, Grunert, H.-P, Heinemann, U, Saenger, W, Hahn, U. Deposit date: 1992-02-19 Release date: 1993-01-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.87 Å) Cite: RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite. J.Mol.Biol., 225, 1992
7JI4	Universal stress protein (USP) domain of KdpD histidine kinase in complex with second messenger c-di-AMP Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, KdpD Authors: Dutta, A, Parashar, V. Deposit date: 2020-07-22 Release date: 2021-05-26 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis of KdpD histidine kinase binding to the second messenger c-di-AMP. J.Biol.Chem., 296, 2021
3HF7	The Crystal Structure of a CBS-domain Pair with Bound AMP from Klebsiella pneumoniae to 2.75A Descriptor: ADENOSINE MONOPHOSPHATE, uncharacterized CBS-domain protein Authors: Stein, A.J, Nocek, B, Wu, R, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2009-05-11 Release date: 2009-05-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: The Crystal Structure of a CBS-domain Pair with Bound AMP from Klebsiella pneumoniae to 2.75A To be Published
3EFR	Biotin protein ligase R40G mutant from Aquifex aeolicus in complex with biotin Descriptor: BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION Authors: Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. Deposit date: 2008-09-10 Release date: 2009-06-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
3EFS	Biotin protein ligase from Aquifex aeolicus in complex with biotin and ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, ... Authors: Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. Deposit date: 2008-09-10 Release date: 2009-06-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
8WNJ	Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Ile-AMP Descriptor: ACETATE ION, GLYCEROL, Isoleucine--tRNA ligase, ... Authors: Guo, Y, Li, S, Zhang, T. Deposit date: 2023-10-06 Release date: 2024-02-14 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase. Febs Lett., 598, 2024
1RGL	RNASE T1 MUTANT GLU46GLN BINDS THE INHIBITORS 2'GMP AND 2'AMP AT THE 3' SUBSITE Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 Authors: Granzin, J, Puras-Lutzke, R, Landt, O, Grunert, H.-P, Heinemann, U, Saenger, W, Hahn, U. Deposit date: 1992-02-19 Release date: 1993-01-15 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite. J.Mol.Biol., 225, 1992
4CXA	Crystal structure of the human CDK12-cyclin K complex bound to AMPPNP Descriptor: CYCLIN-DEPENDENT KINASE 12, CYCLIN-K, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Dixon Clarke, S.E, Elkins, J.M, Pike, A.C.W, Nowak, R, Goubin, S, Mahajan, R.P, Kopec, J, Froese, S, Tallant, C, Carpenter, E.P, Mackenzie, A, Faust, B, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A.M, Bountra, C, Bullock, A. Deposit date: 2014-04-04 Release date: 2014-05-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structures of the Cdk12/Cyck Complex with AMP-Pnp Reveal a Flexible C-Terminal Kinase Extension Important for ATP Binding. Sci.Rep., 5, 2015
7UTT	Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination Descriptor: Cyclic GMP-AMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION, ... Authors: Wu, S, Gabelli, S.B, Sohn, J. Deposit date: 2022-04-27 Release date: 2023-05-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination To Be Published
3AJE	Crystal structure of S. tokodaii Sua5 complexed with L-threonine and AMPPNP Descriptor: NITRATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Putative uncharacterized protein ST1526, ... Authors: Kuratani, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2010-06-01 Release date: 2011-04-13 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of Sulfolobus tokodaii Sua5 complexed with L-threonine and AMPPNP Proteins, 79, 2011
4DG3	Crystal structure of R336A mutant of cAMP-dependent protein kinase with unphosphorylated turn motif. Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Steichen, J.M, Yang, J, Taylor, S.S. Deposit date: 2012-01-24 Release date: 2013-02-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Turn motif phosphorylation regulates processing of cAMP-dependent protein kinase To be Published
8GIS	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.5mM Mn2+ Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... Authors: Wu, S, Sohn, J. Deposit date: 2023-03-14 Release date: 2024-04-17 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.46 Å) Cite: The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024

<66676869707172737475767778798081>