1LEV

PORCINE KIDNEY FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH AN AMP-SITE INHIBITOR

Summary for 1LEV

• Entry DOI: 10.2210/pdb1lev/pdb
• Related: 1FBP
• Descriptor: Fructose-1,6-bisphosphatase, 6-O-phosphono-beta-D-fructofuranose, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Sus scrofa (pig)
• Total number of polymer chains: 2
• Total formula weight: 74754.71

Authors

Wright, S.W.,Carlo, A.A.,Danley, D.E.,Hageman, D.L.,Karam, G.A.,Mansour, M.N.,McClure, L.D.,Pandit, J.,Schulte, G.K.,Treadway, J.L.,Wang, I.-K.,Bauer, P.H. (deposition date: 2002-04-10, release date: 2002-10-16, Last modification date: 2023-08-16)

• Primary citation: Wright, S.W.,Carlo, A.A.,Danley, D.E.,Hageman, D.L.,Karam, G.A.,Mansour, M.N.,McClure, L.D.,Pandit, J.,Schulte, G.K.,Treadway, J.L.,Wang, I.-K.,Bauer, P.H.; 3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site.; Bioorg.Med.Chem.Lett., 13:2055-2058, 2003; PubMed: 12781194; DOI: 10.1016/S0960-894X(03)00310-X

Experimental method

X-RAY DIFFRACTION (2.15 Å)