2ZGO
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![BU of 2zgo by Molmil](/molmil-images/mine/2zgo) | Crystal structure of AAL mutant H59Q complex with lactose | Descriptor: | Anti-tumor lectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Li, D.F, Yang, N, Wang, D.C. | Deposit date: | 2008-01-23 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009
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2ZHK
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![BU of 2zhk by Molmil](/molmil-images/mine/2zhk) | Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine dimer (crystal 1) | Descriptor: | Galectin-9, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Nagae, M, Nishi, N, Murata, T, Usui, T, Nakamura, T, Wakatsuki, S, Kato, R. | Deposit date: | 2008-02-06 | Release date: | 2008-12-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain. Glycobiology, 19, 2009
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2ZGP
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2ZHL
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![BU of 2zhl by Molmil](/molmil-images/mine/2zhl) | Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine dimer (crystal 2) | Descriptor: | Galectin-9, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Nagae, M, Nishi, N, Murata, T, Usui, T, Nakamura, T, Wakatsuki, S, Kato, R. | Deposit date: | 2008-02-06 | Release date: | 2008-12-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain. Glycobiology, 19, 2009
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2ZII
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2Q9I
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![BU of 2q9i by Molmil](/molmil-images/mine/2q9i) | |
2Q57
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![BU of 2q57 by Molmil](/molmil-images/mine/2q57) | |
2ZRT
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![BU of 2zrt by Molmil](/molmil-images/mine/2zrt) | Crystal structure of Zn2+-bound form of des3-23ALG-2 | Descriptor: | Programmed cell death protein 6, ZINC ION | Authors: | Suzuki, H, Kawasaki, M, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M. | Deposit date: | 2008-09-01 | Release date: | 2008-11-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2 ACTA CRYSTALLOGR.,SECT.F, 64, 2008
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2Q7W
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![BU of 2q7w by Molmil](/molmil-images/mine/2q7w) | Structural Studies Reveals the Inactivation of E. coli L-aspartate aminotransferase (S)-4,5-amino-dihydro-2-thiophenecarboxylic acid (SADTA) via two mechanisms at pH 6.0 | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ... | Authors: | Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D. | Deposit date: | 2007-06-07 | Release date: | 2007-09-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Inactivation of Escherichia coli l-Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-thiophenecarboxylic Acid Reveals "A Tale of Two Mechanisms". Biochemistry, 46, 2007
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2ZGL
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2ZIR
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![BU of 2zir by Molmil](/molmil-images/mine/2zir) | Crystal Structure of rat protein farnesyltransferase complexed with a benzofuran inhibitor and FPP | Descriptor: | 2-[(S)-(4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-N-morpholin-4-yl-7-phenyl-1-benzofuran-5-carboxamide, FARNESYL DIPHOSPHATE, GLYCEROL, ... | Authors: | Fukami, T.A, Sogabe, S, Nagata, Y, Kondoh, O, Ishii, N. | Deposit date: | 2008-02-22 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors Bioorg.Med.Chem.Lett., 19, 2009
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2Q74
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![BU of 2q74 by Molmil](/molmil-images/mine/2q74) | Mycobacterium tuberculosis SuhB | Descriptor: | Inositol-1-monophosphatase | Authors: | Brown, A.K, Meng, G, Ghadbane, H, Besra, G.S, Futterer, K. | Deposit date: | 2007-06-06 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg2+ Bmc Struct.Biol., 7, 2007
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2Q6W
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2ZJS
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![BU of 2zjs by Molmil](/molmil-images/mine/2zjs) | Crystal Structure of SecYE translocon from Thermus thermophilus with a Fab fragment | Descriptor: | Fab56 (heavy chain), Fab56 (light chain), Preprotein translocase SecE subunit, ... | Authors: | Tsukazaki, T, Mori, H, Fukai, S, Ishitani, R, Perederina, A, Vassylyev, D.G, Ito, K, Nureki, O. | Deposit date: | 2008-03-08 | Release date: | 2008-10-14 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Conformational transition of Sec machinery inferred from bacterial SecYE structures Nature, 455, 2008
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2ZKN
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2PGT
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![BU of 2pgt by Molmil](/molmil-images/mine/2pgt) | CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE P1-1[V104] COMPLEXED WITH (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE | Descriptor: | (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, ... | Authors: | Ji, X. | Deposit date: | 1997-02-17 | Release date: | 1997-09-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase. Biochemistry, 36, 1997
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2QB2
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![BU of 2qb2 by Molmil](/molmil-images/mine/2qb2) | Structural Studies Reveal the Inactivation of E. coli L-aspartate aminotransferase by (s)-4,5-dihydro-2thiophenecarboylic acid (SADTA) via two mechanisms (at pH 7.0). | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ... | Authors: | Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D. | Deposit date: | 2007-06-15 | Release date: | 2007-12-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms". Biochemistry, 46, 2007
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2ZQT
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3C6W
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![BU of 3c6w by Molmil](/molmil-images/mine/3c6w) | Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide | Descriptor: | H3K4me3 histone peptide, Inhibitor of growth protein 5, ZINC ION | Authors: | Champagne, K.S, Pena, P.V, Johnson, K, Kutateladze, T.G. | Deposit date: | 2008-02-05 | Release date: | 2008-06-03 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The crystal structure of the ING5 PHD finger in complex with an H3K4me3 histone peptide. Proteins, 72, 2008
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2N4S
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3CAS
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![BU of 3cas by Molmil](/molmil-images/mine/3cas) | Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione | Descriptor: | 1,2-ETHANEDIOL, 3-oxo-5-beta-steroid 4-dehydrogenase, 4-ANDROSTENE-3-17-DIONE, ... | Authors: | Faucher, F, Cantin, L, Breton, R. | Deposit date: | 2008-02-20 | Release date: | 2008-12-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of Human Delta4-3-Ketosteroid 5beta-Reductase (AKR1D1) Reveal the Presence of an Alternative Binding Site Responsible for Substrate Inhibition (dagger) (,) (double dagger). Biochemistry, 47, 2008
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2NQI
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![BU of 2nqi by Molmil](/molmil-images/mine/2nqi) | Calpain 1 proteolytic core inactivated by WR13(R,R), an epoxysuccinyl-type inhibitor. | Descriptor: | CALCIUM ION, Calpain-1 catalytic subunit, N~2~-[(2S)-2-{[(2R)-4-ETHOXY-2-HYDROXY-4-OXOBUTANOYL]AMINO}PENT-4-ENOYL]-L-ARGINYL-L-TRYPTOPHANAMIDE | Authors: | Cuerrier, D, Davies, P.L, Campbell, R.L, Moldoveanu, T. | Deposit date: | 2006-10-31 | Release date: | 2007-01-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Development of Calpain-specific Inactivators by Screening of Positional Scanning Epoxide Libraries J.Biol.Chem., 282, 2007
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2NC5
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![BU of 2nc5 by Molmil](/molmil-images/mine/2nc5) | Solution Structure of N-Xylosylated Pin1 WW Domain | Descriptor: | Pin1 WW Domain, beta-D-xylopyranose | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | Deposit date: | 2016-03-20 | Release date: | 2016-06-08 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J.Am.Chem.Soc., 138, 2016
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3C94
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![BU of 3c94 by Molmil](/molmil-images/mine/3c94) | ExoI/SSB-Ct complex | Descriptor: | Exodeoxyribonuclease I, MAGNESIUM ION, Single-stranded DNA-binding C-terminal tail peptide | Authors: | Lu, D, Keck, J.L. | Deposit date: | 2008-02-15 | Release date: | 2008-07-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I. Proc.Natl.Acad.Sci.USA, 105, 2008
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2N9Y
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