8WUU
| SpCas9-pegRNA-target DNA complex (pre-initiation) | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (34-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ... | Authors: | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | Deposit date: | 2023-10-21 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 2024
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5DO5
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8IEW
| Cas005-crRNA-DNA complex | Descriptor: | Cas005, DNA (55-MER), RNA (38-MER) | Authors: | Zhang, X, Duan, Z.Q, Zhu, J.K. | Deposit date: | 2023-02-16 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of Cas005-crRNA-DNA complex at 3.1 Angstroms resolution To Be Published
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3IYR
| tmRNA-SmpB: a journey to the center of the bacterial ribosome | Descriptor: | SsrA-binding protein, tmRNA | Authors: | Weis, F, Bron, P, Giudice, E, Rolland, J.P, Thomas, D, Felden, B, Gillet, R. | Deposit date: | 2010-04-16 | Release date: | 2010-10-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | tmRNA-SmpB: a journey to the centre of the bacterial ribosome. Embo J., 29, 2010
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8FTM
| Setx-ssRNA-ADP-SO4 complex | Descriptor: | 5'-3' RNA helicase-like protein, ADENOSINE-5'-DIPHOSPHATE, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ... | Authors: | Williams, R.S, Appel, C.D. | Deposit date: | 2023-01-12 | Release date: | 2023-10-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2. Mol.Cell, 83, 2023
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3IYQ
| tmRNA-SmpB: a journey to the center of the bacterial ribosome | Descriptor: | SsrA-binding protein, tmRNA | Authors: | Weis, F, Bron, P, Giudice, E, Rolland, J.P, Thomas, D, Felden, B, Gillet, R. | Deposit date: | 2010-04-16 | Release date: | 2010-10-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | tmRNA-SmpB: a journey to the centre of the bacterial ribosome. Embo J., 29, 2010
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4X5O
| Human histidine tRNA synthetase | Descriptor: | Histidine--tRNA ligase, cytoplasmic | Authors: | Kim, Y.K, Jeon, Y.H. | Deposit date: | 2014-12-05 | Release date: | 2015-11-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural characteristics of human histidyl-tRNA synthetase Biodesign, 2, 2015
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5KKG
| Crystal structure of E72A mutant of ancestral protein ancMT of ADP-dependent sugar kinases family | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCEROL, IODIDE ION, ... | Authors: | Castro-Fernandez, V, Herrera-Morande, A, Zamora, R, Merino, F, Pereira, H.M, Brandao-Neto, J, Garratt, R, Guixe, V. | Deposit date: | 2016-06-21 | Release date: | 2017-07-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.608 Å) | Cite: | Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases. J. Biol. Chem., 292, 2017
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6BJV
| CIRV p19 protein in complex with siRNA | Descriptor: | RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19 | Authors: | Foss, D.V, Schirle, N, Pezacki, J.P, Macrae, I.J. | Deposit date: | 2017-11-07 | Release date: | 2019-01-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.198 Å) | Cite: | Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs. Febs Open Bio, 9, 2019
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6BJG
| CIRV p19 mutant T111H in complex with siRNA | Descriptor: | RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19 | Authors: | Foss, D.V, Schirle, N, Pezacki, J.P, Macrae, I.J. | Deposit date: | 2017-11-06 | Release date: | 2019-01-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs. Febs Open Bio, 9, 2019
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5VAJ
| BhRNase H - amide-RNA/DNA complex | Descriptor: | ACETATE ION, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), GLYCEROL, ... | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2017-03-27 | Release date: | 2017-09-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs. Nucleic Acids Res., 45, 2017
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3TUP
| Crystal structure of human mitochondrial PheRS complexed with tRNAPhe in the active open state | Descriptor: | Phenylalanyl-tRNA synthetase, mitochondrial, Thermus thermophilus tRNAPhe | Authors: | Safro, M, Klipcan, L, Moor, N, Finarov, I, Kessler, N, Sukhanova, M. | Deposit date: | 2011-09-17 | Release date: | 2011-11-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal Structure of Human Mitochondrial PheRS Complexed with tRNA(Phe) in the Active "Open" State. J.Mol.Biol., 415, 2012
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6E9F
| EsCas13d-crRNA-target RNA ternary complex | Descriptor: | EsCas13d, MAGNESIUM ION, RNA (27-MER), ... | Authors: | Zhang, C, Lyumkis, D. | Deposit date: | 2018-08-01 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d. Cell, 175, 2018
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2M8D
| Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3' | Descriptor: | RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1 | Authors: | Clery, A, Sinha, R, Anczukow, O, Corrionero, A, Moursy, A, Daubner, G, Valcarcel, J, Krainer, A.R, Allain, F.H.T. | Deposit date: | 2013-05-17 | Release date: | 2013-07-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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6Y6M
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6E9E
| EsCas13d-crRNA binary complex | Descriptor: | EsCas13d, MAGNESIUM ION, crRNA (52-MER) | Authors: | Zhang, C, Lyumkis, D. | Deposit date: | 2018-08-01 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d. Cell, 175, 2018
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6Y96
| solution structure of cold-shock domain 9 of drosophila Upstream of N-Ras (Unr) | Descriptor: | Upstream of N-ras, isoform A | Authors: | Sweetapple, L.J, Hollmann, N.M, Simon, B, Hennig, J. | Deposit date: | 2020-03-06 | Release date: | 2020-07-29 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras. Cell Rep, 32, 2020
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6Y6E
| drosophila Unr CSD456 | Descriptor: | ETHYL MERCURY ION, Upstream of N-ras, isoform A | Authors: | Hollmann, N.M, Jagtap, P.K.A, Hennig, J. | Deposit date: | 2020-02-26 | Release date: | 2020-07-29 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras. Cell Rep, 32, 2020
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6Y4H
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1I6U
| RNA-PROTEIN INTERACTIONS: THE CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN S8/RRNA COMPLEX FROM METHANOCOCCUS JANNASCHII | Descriptor: | 16S RRNA FRAGMENT, 30S RIBOSOMAL PROTEIN S8P, SULFATE ION | Authors: | Tishchenko, S, Nikulin, A, Fomenkova, N, Nevskaya, N, Nikonov, O, Dumas, P, Moine, H, Ehresmann, B, Ehresmann, C, Piendl, W, Lamzin, V, Garber, M, Nikonov, S. | Deposit date: | 2001-03-05 | Release date: | 2001-08-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Detailed analysis of RNA-protein interactions within the ribosomal protein S8-rRNA complex from the archaeon Methanococcus jannaschii. J.Mol.Biol., 311, 2001
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4K4X
| Coxsackievirus B3 polymerase elongation complex (r2_form), rna | Descriptor: | GLYCEROL, MAGNESIUM ION, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), ... | Authors: | Gong, P, Peersen, O.B. | Deposit date: | 2013-04-12 | Release date: | 2013-05-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
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1OO7
| DNA.RNA HYBRID DUPLEX CONTAINING A 5-PROPYNE DNA STRAND AND PURINE-RICH RNA STRAND, NMR, 4 STRUCTURES | Descriptor: | 5'-D(*GP*(5PC)P*(PDU)P*(PDU)P*(5PC)P*(PDU)P*(5PC)P*(PDU)P*(PDU)P*C)-3', 5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3' | Authors: | Gyi, J.I, Gao, D, Conn, G.L, Trent, J.O, Brown, T, Lane, A.N. | Deposit date: | 2003-03-03 | Release date: | 2003-11-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications Nucleic Acids Res., 31, 2003
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3AM1
| Crystal structure of O-Phosphoseryl-tRNA kinase complexed with anticodon-stem/loop truncated tRNA(Sec) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ASL-truncated tRNA, L-seryl-tRNA(Sec) kinase, ... | Authors: | Araiso, Y, Ishitani, R, Nureki, O. | Deposit date: | 2010-08-11 | Release date: | 2010-12-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA(Sec) Nucleic Acids Res., 39, 2011
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4AL6
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2NNW
| Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs | Descriptor: | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein | Authors: | Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H. | Deposit date: | 2006-10-24 | Release date: | 2007-08-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs. J.Mol.Biol., 371, 2007
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