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5MF0
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BU of 5mf0 by Molmil
Crystal structure of Smad4-MH1 bound to the GGCCG site.
Descriptor: CHLORIDE ION, DNA (5'-D(P*AP*CP*GP*GP*GP*CP*CP*GP*CP*GP*GP*CP*CP*CP*GP*T)-3'), MH1 domain of human Smad4, ...
Authors:Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.
Nat Commun, 8, 2017
5OAY
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BU of 5oay by Molmil
M. tuberculosis [4Fe-4S] protein WhiB1 is a four-helix bundle that forms a NO-sensitive complex with sigmaA and regulates the major virulence factor ESX-1
Descriptor: IRON/SULFUR CLUSTER, Transcriptional regulator WhiB1
Authors:Williamson, M.P, Green, J, Hounslow, A.M.
Deposit date:2017-06-25
Release date:2018-01-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of a Wbl protein and implications for NO sensing by M. tuberculosis.
Nat Commun, 8, 2017
5OKC
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BU of 5okc by Molmil
Crystal structure of the Ctf18-1-8 module from Ctf18-RFC
Descriptor: 1,2-ETHANEDIOL, Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, ...
Authors:Grabarczyk, D.B, Kisker, C.
Deposit date:2017-07-25
Release date:2017-12-20
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Recruitment of Ctf18-RFC to the Replisome.
Structure, 26, 2018
5MEZ
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BU of 5mez by Molmil
Crystal structure of Smad4-MH1 bound to the GGCT site.
Descriptor: CHLORIDE ION, DNA (5'-D(P*GP*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP*A)-3'), MH1 domain of human Smad4, ...
Authors:Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.
Nat Commun, 8, 2017
5SY5
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BU of 5sy5 by Molmil
Crystal Structure of the Heterodimeric NPAS1-ARNT Complex
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1
Authors:Wu, D, Su, X, Potluri, N, Kim, Y, Rastinejad, F.
Deposit date:2016-08-10
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
7P6F
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BU of 7p6f by Molmil
1.93 A resolution X-ray crystal structure of the transcriptional regulator SrnR from Streptomyces griseus
Descriptor: ACETATE ION, SODIUM ION, Transcriptional regulator SrnR
Authors:Mazzei, L, Ciurli, S.
Deposit date:2021-07-16
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structure, dynamics, and function of SrnR, a transcription factor for nickel-dependent gene expression.
Metallomics, 13, 2021
5FV7
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BU of 5fv7 by Molmil
Human Fen1 in complex with an N-hydroxyurea compound
Descriptor: 1-[(2S)-2,3-dihydro-1,4-benzodioxin-2-ylmethyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione, FLAP ENDONUCLEASE 1, MAGNESIUM ION
Authors:Exell, J.C, Thompson, M.J, Finger, L.D, Shaw, S.K, Abbott, W.M, McWhirter, C, Debreczeni, J.E, Jones, C.D, Nissink, J.W.M, Ward, T.A, Sioberg, C.W.L, Molina, D.M, Durant, S.T, Grasby, J.A.
Deposit date:2016-02-03
Release date:2016-08-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Cellular Active N-Hydroxyurea Fen1 Inhibitors Block Substrate Entry to the Active Site
Nat.Chem.Biol., 12, 2016
6QKQ
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BU of 6qkq by Molmil
NMR solution structure of LSR2-T112D binding domain.
Descriptor: Nucleoid-associated protein Lsr2
Authors:Barthe, P, Cohen-Gonsaud, M, Mukamolova, G.V.
Deposit date:2019-01-30
Release date:2019-07-17
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112.
Mol.Microbiol., 112, 2019
6QKP
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BU of 6qkp by Molmil
NMR solution structure of LSR2 binding domain.
Descriptor: Nucleoid-associated protein Lsr2
Authors:Barthe, P, Cohen-Gonsaud, M, Mukamolova, G.V.
Deposit date:2019-01-30
Release date:2019-07-17
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112.
Mol.Microbiol., 112, 2019
6SRN
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BU of 6srn by Molmil
Structural basis for control of antibiotic production by bacterial hormones
Descriptor: 4-(Hydroxymethyl)-2-propylfuran-3-carboxylic acid, GLYCEROL, TetR family transcriptional regulator
Authors:Fulop, V.
Deposit date:2019-09-05
Release date:2020-09-30
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for control of antibiotic production by a bacterial hormone.
Nature, 590, 2021
8IQG
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BU of 8iqg by Molmil
Cryo-EM structure of the monomeric human CAF1-H3-H4 complex
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Xu, R.M.
Deposit date:2023-03-16
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
8IQF
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BU of 8iqf by Molmil
Cryo-EM structure of the dimeric human CAF1-H3-H4 complex
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Xu, R.M.
Deposit date:2023-03-16
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
6K15
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BU of 6k15 by Molmil
RSC substrate-recruitment module
Descriptor: Chromatin structure-remodeling complex protein RSC3, Chromatin structure-remodeling complex protein RSC30, Chromatin structure-remodeling complex protein RSC58, ...
Authors:Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C.
Deposit date:2019-05-09
Release date:2019-11-13
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
5X80
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BU of 5x80 by Molmil
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN RV2887 COMPLEX WITH SALICYLIC ACID
Descriptor: 2-HYDROXYBENZOIC ACID, SULFATE ION, Uncharacterized HTH-type transcriptional regulator Rv2887
Authors:Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J.
Deposit date:2017-02-28
Release date:2017-08-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
3BPX
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BU of 3bpx by Molmil
Crystal Structure of MarR
Descriptor: 2-HYDROXYBENZOIC ACID, SODIUM ION, Transcriptional regulator
Authors:Saridakis, V, Shahinas, D, Xu, X, Christendat, D.
Deposit date:2007-12-19
Release date:2008-05-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum.
J.Mol.Biol., 377, 2008
4NC7
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BU of 4nc7 by Molmil
N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION
Authors:Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M.
Deposit date:2013-10-24
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
3BPV
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BU of 3bpv by Molmil
Crystal Structure of MarR
Descriptor: Transcriptional regulator
Authors:Saridakis, V, Shahinas, D, Xu, X, Christendat, D.
Deposit date:2007-12-19
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum.
J.Mol.Biol., 377, 2008
4ETS
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BU of 4ets by Molmil
Crystal structure of Campylobacter jejuni ferric uptake regulator
Descriptor: CHLORIDE ION, Ferric uptake regulation protein, ZINC ION
Authors:Sarvan, S, Brunzelle, J.B, Couture, J.-F.
Deposit date:2012-04-24
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulation.
Proc.Natl.Acad.Sci.USA, 109, 2012
6RLB
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BU of 6rlb by Molmil
Structure of the dynein-2 complex; tail domain
Descriptor: Cytoplasmic dynein 2 light intermediate chain 1, Dynein light chain 1, cytoplasmic, ...
Authors:Toropova, K, Zalyte, R, Mukhopadhyay, A.G, Mladenov, M, Carter, A.P, Roberts, A.J.
Deposit date:2019-05-01
Release date:2019-08-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of the dynein-2 complex and its assembly with intraflagellar transport trains.
Nat.Struct.Mol.Biol., 26, 2019
8SXU
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BU of 8sxu by Molmil
Structure of LINE-1 ORF2p with an oligo(A) template
Descriptor: LINE-1 retrotransposable element ORF2 protein, RNA (25-MER)
Authors:van Eeuwen, T, Taylor, M.S, Rout, M.P.
Deposit date:2023-05-24
Release date:2024-01-10
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
5M4S
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BU of 5m4s by Molmil
Transcription factor TFIIA as a single chain protein
Descriptor: Transcription initiation factor IIA subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 1
Authors:Kandiah, E, Gupta, K.
Deposit date:2016-10-19
Release date:2017-11-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Elife, 6, 2017
3FMS
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BU of 3fms by Molmil
Crystal structure of TM0439, a GntR transcriptional regulator
Descriptor: ACETATE ION, NICKEL (II) ION, Transcriptional regulator, ...
Authors:Zheng, M, Cooper, D.R, Yu, M, Hung, L.-W, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2008-12-22
Release date:2009-02-10
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.
Acta Crystallogr.,Sect.D, 65, 2009
6P0F
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BU of 6p0f by Molmil
N-terminal domain of Thermococcus Gammatolerans McrB
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AMMONIUM ION, GTPase subunit of restriction endonuclease, ...
Authors:Hosford, C.J, Chappie, J.S.
Deposit date:2019-05-17
Release date:2019-12-18
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.683 Å)
Cite:The structure of theThermococcus gammatoleransMcrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs.
J.Biol.Chem., 295, 2020
3VOD
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BU of 3vod by Molmil
Crystal Structure of mutant MarR C80S from E.coli
Descriptor: Multiple antibiotic resistance protein marR
Authors:Lou, H, Zhu, R, Hao, Z.
Deposit date:2012-01-21
Release date:2013-03-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli.
Nat.Chem.Biol., 10, 2014
2J4D
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BU of 2j4d by Molmil
Cryptochrome 3 from Arabidopsis thaliana
Descriptor: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, CRYPTOCHROME DASH, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Klar, T, Pokorny, R, Batschauer, A, Essen, L.-O.
Deposit date:2006-08-28
Release date:2007-06-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cryptochrome 3 from Arabidopsis Thaliana: Structural and Functional Analysis of its Complex with a Folate Light Antenna
J.Mol.Biol., 366, 2007

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