5V7G
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![BU of 5v7g by Molmil](/molmil-images/mine/5v7g) | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in complex with NADPH and oxalate | Descriptor: | CHLORIDE ION, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Shabalin, I.G, Mason, D.V, Handing, K.B, Kutner, J, Matelska, D, Cooper, D.R, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2017-03-20 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry, 57, 2018
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5V72
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![BU of 5v72 by Molmil](/molmil-images/mine/5v72) | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in complex with citrate | Descriptor: | CHLORIDE ION, CITRIC ACID, GLYCEROL, ... | Authors: | Shabalin, I.G, Handing, K.B, Gasiorowska, O.A, Cooper, D.R, Matelska, D, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2017-03-17 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry, 57, 2018
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5UOG
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![BU of 5uog by Molmil](/molmil-images/mine/5uog) | Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase SMc04462 (SmGhrB) from Sinorhizobium meliloti in apo form | Descriptor: | NADPH-dependent glyoxylate/hydroxypyruvate reductase, SULFATE ION | Authors: | Shabalin, I.G, Handing, K.B, Gasiorowska, O.A, Cooper, D.R, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2017-01-31 | Release date: | 2017-02-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry, 57, 2018
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2OME
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![BU of 2ome by Molmil](/molmil-images/mine/2ome) | Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H) | Descriptor: | C-terminal-binding protein 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Pilka, E.S, Guo, K, Rojkova, A, Debreczeni, J.E, Kavanagh, K.L, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2007-01-22 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human CTBP2 dehydrogenase complexed with NAD(H) To be Published
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2GO1
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![BU of 2go1 by Molmil](/molmil-images/mine/2go1) | NAD-dependent formate dehydrogenase from Pseudomonas sp.101 | Descriptor: | NAD-dependent formate dehydrogenase, SULFATE ION | Authors: | Filippova, E.V, Polyakov, K.M, Tikhonova, T.V, Stekhanova, T.N, Boiko, K.M, Popov, V.O. | Deposit date: | 2006-04-12 | Release date: | 2006-05-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a new crystal modification of the bacterial NAD-dependent formate dehydrogenase with a resolution of 2.1 A Crystallography reports, 50, 2005
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2NAD
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![BU of 2nad by Molmil](/molmil-images/mine/2nad) | HIGH RESOLUTION STRUCTURES OF HOLO AND APO FORMATE DEHYDROGENASE | Descriptor: | AZIDE ION, NAD-DEPENDENT FORMATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Lamzin, V.S, Dauter, Z, Popov, V.O, Harutyunyan, E.H, Wilson, K.S. | Deposit date: | 1994-07-06 | Release date: | 1995-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | High resolution structures of holo and apo formate dehydrogenase. J.Mol.Biol., 236, 1994
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2NAC
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![BU of 2nac by Molmil](/molmil-images/mine/2nac) | HIGH RESOLUTION STRUCTURES OF HOLO AND APO FORMATE DEHYDROGENASE | Descriptor: | NAD-DEPENDENT FORMATE DEHYDROGENASE, SULFATE ION | Authors: | Lamzin, V.S, Dauter, Z, Popov, V.O, Harutyunyan, E.H, Wilson, K.S. | Deposit date: | 1994-07-06 | Release date: | 1995-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High resolution structures of holo and apo formate dehydrogenase. J.Mol.Biol., 236, 1994
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2P9C
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![BU of 2p9c by Molmil](/molmil-images/mine/2p9c) | |
2PA3
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![BU of 2pa3 by Molmil](/molmil-images/mine/2pa3) | |
2P9G
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![BU of 2p9g by Molmil](/molmil-images/mine/2p9g) | |
2P9E
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![BU of 2p9e by Molmil](/molmil-images/mine/2p9e) | |
2GCG
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![BU of 2gcg by Molmil](/molmil-images/mine/2gcg) | Ternary Crystal Structure of Human Glyoxylate Reductase/Hydroxypyruvate Reductase | Descriptor: | (2R)-2,3-DIHYDROXYPROPANOIC ACID, Glyoxylate reductase/hydroxypyruvate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L. | Deposit date: | 2006-03-14 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase J.Mol.Biol., 360, 2006
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2GUG
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![BU of 2gug by Molmil](/molmil-images/mine/2gug) | NAD-dependent formate dehydrogenase from Pseudomonas sp.101 in complex with formate | Descriptor: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, Formate dehydrogenase, ... | Authors: | Filippova, E.V, Polyakov, K.M, Tikhonova, T.V, Boiko, K.M, Tishkov, V.I, Popov, V.O. | Deposit date: | 2006-04-30 | Release date: | 2006-05-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal structure of the complex of NAD-dependent formate dehydrogenase from
metylotrophic bacterium Pseudomonas sp.101 with formate. KRISTALLOGRAFIYA, 51, 2006
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2GSD
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![BU of 2gsd by Molmil](/molmil-images/mine/2gsd) | NAD-dependent formate dehydrogenase from bacterium Moraxella sp.C2 in complex with NAD and azide | Descriptor: | AZIDE ION, NAD-dependent formate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Filippova, E.V, Polyakov, K.M, Tikhonova, T.V, Sadykhov, I.G, Shabalin, I.G, Tishkov, V.I, Popov, V.O. | Deposit date: | 2006-04-26 | Release date: | 2006-05-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of the apo and holo forms of formate dehydrogenase from the bacterium Moraxella sp. C-1: towards understanding the mechanism of the closure of the interdomain cleft. Acta Crystallogr.,Sect.D, 65, 2009
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2H1S
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2Q50
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![BU of 2q50 by Molmil](/molmil-images/mine/2q50) | Ensemble refinement of the protein crystal structure of a glyoxylate/hydroxypyruvate reductase from Homo sapiens | Descriptor: | Glyoxylate reductase/hydroxypyruvate reductase | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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4XKJ
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4XYG
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4XYB
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![BU of 4xyb by Molmil](/molmil-images/mine/4xyb) | GRANULICELLA M. FORMATE DEHYDROGENASE (FDH) IN COMPLEX WITH NADP(+) AND NaN3 | Descriptor: | 1,2-ETHANEDIOL, AZIDE ION, Formate dehydrogenase, ... | Authors: | Cendron, L, Fogal, S, Beneventi, E, Bergantino, E. | Deposit date: | 2015-02-02 | Release date: | 2015-07-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Structural basis for double cofactor specificity in a new formate dehydrogenase from the acidobacterium Granulicella mallensis MP5ACTX8. Appl.Microbiol.Biotechnol., 99, 2015
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4ZGS
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![BU of 4zgs by Molmil](/molmil-images/mine/4zgs) | Identification of the pyruvate reductase of Chlamydomonas reinhardtii | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative D-lactate dehydrogenase | Authors: | Burgess, S.J, Hussein, T, Yeoman, J.A, Iamshanova, O, Boehm, M, Bundy, J, Bialek, W, Murray, J.W, Nixon, P.J. | Deposit date: | 2015-04-23 | Release date: | 2015-12-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.461 Å) | Cite: | Identification of the Elusive Pyruvate Reductase of Chlamydomonas reinhardtii Chloroplasts. Plant Cell.Physiol., 57, 2016
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5AOV
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4XYE
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![BU of 4xye by Molmil](/molmil-images/mine/4xye) | GRANULICELLA M. FORMATE DEHYDROGENASE (FDH) IN COMPLEX WITH NAD(+) | Descriptor: | Formate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Cendron, L, Fogal, S, Beneventi, E, Bergantino, E. | Deposit date: | 2015-02-02 | Release date: | 2015-07-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for double cofactor specificity in a new formate dehydrogenase from the acidobacterium Granulicella mallensis MP5ACTX8. Appl.Microbiol.Biotechnol., 99, 2015
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6T8C
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![BU of 6t8c by Molmil](/molmil-images/mine/6t8c) | Crystal structure of formate dehydrogenase FDH2 enzyme from Granulicella mallensis MP5ACTX8 in the apo form. | Descriptor: | Formate dehydrogenase | Authors: | Robescu, M.S, Rubini, R, Filippini, F, Bergantino, B, Cendron, L. | Deposit date: | 2019-10-24 | Release date: | 2020-08-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | From the Amelioration of a NADP+-dependent Formate Dehydrogenase to the Discovery of a New Enzyme: Round Trip from Theory to Practice Chemcatchem, 2020
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5N53
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![BU of 5n53 by Molmil](/molmil-images/mine/5n53) | Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with N-(3-chloro-4-methoxyphenyl) acetamide | Descriptor: | D-3-phosphoglycerate dehydrogenase, ~{N}-(3-chloranyl-4-methoxy-phenyl)ethanamide | Authors: | Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. | Deposit date: | 2017-02-12 | Release date: | 2017-04-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
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6T94
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![BU of 6t94 by Molmil](/molmil-images/mine/6t94) | NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH. | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Isupov, M.N, Yelmazer, B, De Rose, S.A, Littlechild, J.A. | Deposit date: | 2019-10-25 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structural insights into the NAD + -dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD + ternary complex of the Chaetomium thermophilum enzyme. J.Struct.Biol., 212, 2020
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