2GCG

Ternary Crystal Structure of Human Glyoxylate Reductase/Hydroxypyruvate Reductase

Summary for 2GCG

Entry DOI	10.2210/pdb2gcg/pdb
Descriptor	Glyoxylate reductase/hydroxypyruvate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2R)-2,3-DIHYDROXYPROPANOIC ACID, ... (5 entities in total)
Functional Keywords	nad(p) rossmann fold, formate/glycerate dehydrogenase substrate-binding domain, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	147151.61
Authors	Booth, M.P.S.,Conners, R.,Rumsby, G.,Brady, R.L. (deposition date: 2006-03-14, release date: 2006-07-18, Last modification date: 2023-10-25)
Primary citation	Booth, M.P.S.,Conners, R.,Rumsby, G.,Brady, R.L. Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase J.Mol.Biol., 360:178-189, 2006 Cited by PubMed: 16756993 DOI: 10.1016/j.jmb.2006.05.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation