PDB: 73332 resultsInfo pagesStatus searchChemie searchBIRD

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8GLP	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. Deposit date: 2023-03-22 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (1.67 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
6GZ5	tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-3 (TI-POST-3) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... Authors: Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V. Deposit date: 2018-07-03 Release date: 2018-12-05 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis. Cell Rep, 25, 2018
6GZ4	tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-2 (TI-POST-2) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... Authors: Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V. Deposit date: 2018-07-03 Release date: 2018-12-05 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis. Cell Rep, 25, 2018
4V91	Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES Descriptor: 25S RRNA, 5.8S RRNA, 5S RRNA, ... Authors: Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V. Deposit date: 2014-03-21 Release date: 2014-07-09 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome. Cell(Cambridge,Mass.), 157, 2014
6YST	Structure of the P+9 ArfB-ribosome complex with P/E hybrid tRNA in the post-hydrolysis state Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. Deposit date: 2020-04-23 Release date: 2020-08-19 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nat Commun, 11, 2020
6UZ7	K.lactis 80S ribosome with p/PE tRNA and eIF5B Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... Authors: Fernandez, I.S, Huang, B.Y. Deposit date: 2019-11-14 Release date: 2020-01-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation. Proc.Natl.Acad.Sci.USA, 117, 2020
7R9F	Wild-type yeast Pseudouridine Synthase, PUS1, bound to 5-Fluorouracil RNA Descriptor: RNA (5'-R(*UP*AP*AP*UP*CP*GP*GP*GP*AP*UP*UP*CP*CP*GP*GP*AP*UP*A)-3'), SULFATE ION, tRNA pseudouridine synthase 1 Authors: Doyle, L.A, Stoddard, B.L. Deposit date: 2021-06-29 Release date: 2021-12-15 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.89 Å) Cite: The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1. Plos One, 18, 2023
5M3M	Free monomeric RNA polymerase I at 4.0A resolution Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Neyer, S, Kunz, M, Geiss, C, Hantsche, M, Hodirnau, V.-V, Seybert, A, Engel, C, Scheffer, M.P, Cramer, P, Frangakis, A.S. Deposit date: 2016-10-15 Release date: 2016-11-23 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature, 540, 2016
5OC6	Crystal structure of human tRNA-dihydrouridine(20) synthase dsRBD in complex with a 22 nucleotide dsRNA Descriptor: RNA, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like Authors: Bou-nader, C, Pecqueur, L, Hamdane, D. Deposit date: 2017-06-29 Release date: 2018-12-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Molecular basis for transfer RNA recognition by the double-stranded RNA-binding domain of human dihydrouridine synthase 2. Nucleic Acids Res., 47, 2019
8FNI	Cryo-EM structure of RNase-treated RESC-B in trypanosomal RNA editing Descriptor: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ... Authors: Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. Deposit date: 2022-12-27 Release date: 2023-07-19 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381, 2023
8FNK	Cryo-EM structure of RNase-untreated RESC-B in trypanosomal RNA editing Descriptor: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ... Authors: Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. Deposit date: 2022-12-27 Release date: 2023-07-19 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381, 2023
7ZRZ	Structure of the human tRNA splicing endonuclease defines substrate recognition Descriptor: pre-tRNA Arg TCT 3-2, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen2, ... Authors: Sekulovski, S, Trowitzsch, S. Deposit date: 2022-05-05 Release date: 2023-05-17 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN. Nat.Struct.Mol.Biol., 30, 2023
5D0U	Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... Authors: Tauchert, M.J, Ficner, R. Deposit date: 2015-08-03 Release date: 2016-02-10 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.919 Å) Cite: Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 72, 2016
4P5J	Crystal structure of the tRNA-like structure from Turnip Yellow Mosaic Virus (TYMV), a tRNA mimicking RNA Descriptor: IRIDIUM HEXAMMINE ION, MAGNESIUM ION, SPERMINE, ... Authors: Colussi, T.M, Costantino, D.A, Hammond, J.A, Ruehle, G.M, Nix, J.C, Kieft, J.S. Deposit date: 2014-03-17 Release date: 2014-06-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.9912 Å) Cite: The structural basis of transfer RNA mimicry and conformational plasticity by a viral RNA. Nature, 511, 2014
8EG0	CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA and SAH Descriptor: RNA (65-MER), S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase, ... Authors: Ruiz-Arroyo, V.M, Nam, Y. Deposit date: 2022-09-10 Release date: 2023-01-11 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: Structures and mechanisms of tRNA methylation by METTL1-WDR4. Nature, 613, 2023
3MQK	Cbf5-Nop10-Gar1 complex binding with 17mer RNA containing ACA trinucleotide Descriptor: RNA (5'-R(P*CP*GP*AP*UP*CP*CP*AP*CP*A)-3'), RNA (5'-R(P*GP*UP*UP*CP*GP*AP*UP*CP*CP*AP*CP*AP*G)-3'), Ribosome biogenesis protein Nop10, ... Authors: Zhou, J, Liang, B, Li, H. Deposit date: 2010-04-28 Release date: 2010-12-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and functional evidence of high specificity of Cbf5 for ACA trinucleotide. Rna, 17, 2011
5X6B	Crystal structure of SepCysE-SepCysS in complex with tRNACys from Methanocaldococcus jannaschii Descriptor: O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481, tRNACys Authors: Chen, M, Kato, K, Yao, M. Deposit date: 2017-02-21 Release date: 2017-12-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.596 Å) Cite: Structural basis for tRNA-dependent cysteine biosynthesis Nat Commun, 8, 2017
8D9L	CryoEM structure of human METTL1-WDR4 in complex with Lys-tRNA and SAM Descriptor: Lys-tRNA, S-ADENOSYLMETHIONINE, tRNA (guanine-N(7)-)-methyltransferase, ... Authors: Ruiz-Arroyo, V.M, Nam, Y. Deposit date: 2022-06-10 Release date: 2023-01-11 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (4.04 Å) Cite: Structures and mechanisms of tRNA methylation by METTL1-WDR4. Nature, 613, 2023
4A3J	RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP Descriptor: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3', 5'-D(*GP*TP*AP*GP*AP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', 5'-R(*CP*AP)-3', ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structural Basis of Initial RNA Polymerase II Transcription. Embo J., 30, 2011
4A3C	RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-11-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
4A3D	RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
4A3K	RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural Basis of Initial RNA Polymerase II Transcription. Embo J., 30, 2011
4A3G	RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2012-02-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
4A3L	RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
4A3E	RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011

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