4PG3

Crystal structure of KRS complexed with inhibitor

Summary for 4PG3

Entry DOI	10.2210/pdb4pg3/pdb
Descriptor	Lysine--tRNA ligase, LYSINE, cladosporin, ... (4 entities in total)
Functional Keywords	inhibitor, krs, complex, ligase-ligase inhibitor complex, ligase/ligase inhibitor
Biological source	Plasmodium falciparum
Total number of polymer chains	4
Total formula weight	236585.82
Authors	Sharma, A.,Yogavel, M.,Khan, S.,Sharma, A.,Belrhali, H. (deposition date: 2014-05-01, release date: 2014-07-16, Last modification date: 2023-09-27)
Primary citation	Khan, S.,Sharma, A.,Belrhali, H.,Yogavel, M.,Sharma, A. Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin. J. Struct. Funct. Genomics, 15:63-71, 2014 Cited by PubMed: 24935905 DOI: 10.1007/s10969-014-9182-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.696 Å)

Structure validation