4WT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wt8 by Molmil](/molmil-images/mine/4wt8) | Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex | Descriptor: | 23S rRNA (2899-MER), 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Amunts, A, Fiedorczuk, K, Ramakrishnan, V. | Deposit date: | 2014-10-29 | Release date: | 2015-01-21 | Last modified: | 2018-07-18 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics. J.Mol.Biol., 427, 2015
|
|
4WWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4www by Molmil](/molmil-images/mine/4www) | Crystal structure of the E. coli ribosome bound to CEM-101 | Descriptor: | (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ... | Authors: | Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S. | Deposit date: | 2014-11-12 | Release date: | 2014-12-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob. Agents Chemother., 54, 2010
|
|
7CKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ckb by Molmil](/molmil-images/mine/7ckb) | Simplified Alpha-Carboxysome, T=3 | Descriptor: | Major carboxysome shell protein 1A, Unidentified carboxysome polypeptide | Authors: | Tan, Y.Q, Ali, S, Xue, B, Robinson, R.C, Narita, A, Yew, W.S. | Deposit date: | 2020-07-16 | Release date: | 2021-08-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structure of a Minimal alpha-Carboxysome-Derived Shell and Its Utility in Enzyme Stabilization. Biomacromolecules, 22, 2021
|
|
7CKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ckc by Molmil](/molmil-images/mine/7ckc) | Simplified Alpha-Carboxysome, T=4 | Descriptor: | Major carboxysome shell protein 1A, Unidentified carboxysome polypeptide | Authors: | Tan, Y.Q, Ali, S, Xue, B, Robinson, R.C, Narita, A, Yew, W.S. | Deposit date: | 2020-07-16 | Release date: | 2021-08-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of a Minimal alpha-Carboxysome-Derived Shell and Its Utility in Enzyme Stabilization. Biomacromolecules, 22, 2021
|
|
4WSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wsd by Molmil](/molmil-images/mine/4wsd) | Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site and with antibiotic paromomycin. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-27 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
4WZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wzd by Molmil](/molmil-images/mine/4wzd) | Complex of 70S ribosome with cognate tRNA-Tyr in the P-site | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-11-19 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
4WR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wr8 by Molmil](/molmil-images/mine/4wr8) | Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180) | Descriptor: | 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ... | Authors: | Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L. | Deposit date: | 2014-10-23 | Release date: | 2015-03-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor. J.Am.Chem.Soc., 137, 2015
|
|
4WRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wro by Molmil](/molmil-images/mine/4wro) | Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-24 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
4WSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wsm by Molmil](/molmil-images/mine/4wsm) | Complex of 70S ribosome with tRNA-Leu and mRNA with G-U mismatch in the first position in the A- and P-sites | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-28 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
7D5W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d5w by Molmil](/molmil-images/mine/7d5w) | Bovine heart cytochrome c oxidase in a catalytic intermediate of O at 1.84 angstrom resolution | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Tsukihara, T, Shimada, A. | Deposit date: | 2020-09-28 | Release date: | 2021-07-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Critical roles of the Cu B site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates. J.Biol.Chem., 297, 2021
|
|
7D5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d5x by Molmil](/molmil-images/mine/7d5x) | Bovine heart cytochrome c oxidase in a catalytic intermediate, IO10, at 1.74 angstrom resolution | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Tsukihara, T, Shimada, A. | Deposit date: | 2020-09-28 | Release date: | 2021-07-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Critical roles of the Cu B site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates. J.Biol.Chem., 297, 2021
|
|
4WQR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wqr by Molmil](/molmil-images/mine/4wqr) | Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the first position in the A-site. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-22 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
4V83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v83 by Molmil](/molmil-images/mine/4v83) | Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome. | Descriptor: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S. | Deposit date: | 2010-12-13 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4V8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v8n by Molmil](/molmil-images/mine/4v8n) | The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site. | Descriptor: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V. | Deposit date: | 2013-02-13 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome Nat.Struct.Mol.Biol., 20, 2013
|
|
4V9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v9a by Molmil](/molmil-images/mine/4v9a) | Crystal Structure of the 70S ribosome with tetracycline. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Jenner, L, Yusupov, M, Yusupova, G. | Deposit date: | 2012-07-18 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2999 Å) | Cite: | Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4V7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v7u by Molmil](/molmil-images/mine/4v7u) | Crystal structure of the E. coli ribosome bound to erythromycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | Deposit date: | 2010-08-15 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
4V8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v8b by Molmil](/molmil-images/mine/4v8b) | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex). | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2011-12-06 | Release date: | 2014-07-09 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
|
|
4WR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wr6 by Molmil](/molmil-images/mine/4wr6) | Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-23 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
4WZJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wzj by Molmil](/molmil-images/mine/4wzj) | Spliceosomal U4 snRNP core domain | Descriptor: | Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ... | Authors: | Leung, A.K.W, Nagai, K, Li, J. | Deposit date: | 2014-11-19 | Release date: | 2015-01-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis. Nature, 473, 2011
|
|
4WZO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wzo by Molmil](/molmil-images/mine/4wzo) | Complex of 70S ribosome with tRNA-fMet and mRNA | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-11-20 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
|
|
4V56
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v56 by Molmil](/molmil-images/mine/4v56) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. | Deposit date: | 2007-07-21 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.93 Å) | Cite: | A steric block in translation caused by the antibiotic spectinomycin. Acs Chem.Biol., 2, 2007
|
|
4V5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v5g by Molmil](/molmil-images/mine/4v5g) | The crystal structure of the 70S ribosome bound to EF-Tu and tRNA | Descriptor: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | Deposit date: | 2009-09-01 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA. Science, 326, 2009
|
|
4V62
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v62 by Molmil](/molmil-images/mine/4v62) | Crystal Structure of cyanobacterial Photosystem II | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Guskov, A, Gabdulkhakov, A, Kern, J, Broser, M, Zouni, A, Saenger, W. | Deposit date: | 2008-01-17 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cyanobacterial photosystem II at 2.9-A resolution and the role of quinones, lipids, channels and chloride Nat.Struct.Mol.Biol., 16, 2009
|
|
4V6A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v6a by Molmil](/molmil-images/mine/4v6a) | Structure of EF-P bound to the 70S ribosome. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Stanley, R.E, Blaha, G. | Deposit date: | 2009-06-15 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome. Science, 325, 2009
|
|
4V7K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v7k by Molmil](/molmil-images/mine/4v7k) | Structure of RelE nuclease bound to the 70S ribosome (postcleavage state) | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | Deposit date: | 2009-11-02 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell(Cambridge,Mass.), 139, 2009
|
|