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8UII
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Cryo-EM map of human clamp-clamp loader ATAD5-RFC-closed PCNA complex in intermediate state 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-10
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader
Nat.Struct.Mol.Biol., 2024
8UI8
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BU of 8ui8 by Molmil
Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state 3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-10
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader
Nat.Struct.Mol.Biol., 2024
8THC
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BU of 8thc by Molmil
Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to a cracked PCNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ...
Authors:Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H.
Deposit date:2023-07-14
Release date:2024-05-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structure of the PCNA unloader Elg1-RFC.
Sci Adv, 10, 2024
3JA9
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BU of 3ja9 by Molmil
Structure of native human PCNA
Descriptor: Proliferating cell nuclear antigen
Authors:Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y.
Deposit date:2015-05-19
Release date:2015-12-09
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (22 Å)
Cite:Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA
Sci Rep, 5, 2015
3LX2
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BU of 3lx2 by Molmil
Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582
Descriptor: DNA polymerase sliding clamp 2, SULFATE ION
Authors:Ladner, J.E, Kelman, Z, Pan, M.
Deposit date:2010-02-24
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
8Q7I
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PCNA from Chaetomium thermophilum in complex with Fen1 peptide
Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION
Authors:Alphey, M.S, Wolford, C.B, MacNeill, S.A.
Deposit date:2023-08-16
Release date:2023-12-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA.
Front Mol Biosci, 10, 2023
3L0X
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Structure of split yeast PCNA
Descriptor: Proliferating cell nuclear antigen
Authors:Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
Deposit date:2009-12-10
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
6W9W
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BU of 6w9w by Molmil
R80A PCNA mutant defective in BIR
Descriptor: Proliferating cell nuclear antigen
Authors:Ripley, B.M, Washington, M.T.
Deposit date:2020-03-23
Release date:2020-09-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
3LX1
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BU of 3lx1 by Molmil
Crystal Structure analysis of PCNA1 from Thermococcus kodakaraensis tk0535
Descriptor: DNA polymerase sliding clamp 1, SULFATE ION
Authors:Ladner, J.E, Kelman, Z, Pan, M.
Deposit date:2010-02-24
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
6VVO
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BU of 6vvo by Molmil
Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A.
Deposit date:2020-02-18
Release date:2020-02-26
Last modified:2020-03-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism
Biorxiv, 2020
1UD9
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BU of 1ud9 by Molmil
Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii
Descriptor: DNA polymerase sliding clamp A, ZINC ION
Authors:Tanabe, E, Yasutake, Y, Tanaka, Y, Yao, M, Tsumoto, K, Kumagai, I, Tanaka, I.
Deposit date:2003-04-28
Release date:2004-06-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) Homolog From Sulfolobus tokodaii
To be published
2ZVV
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BU of 2zvv by Molmil
Crystal structure of Proliferating cellular nuclear antigen 1 and Short peptide from human P21
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cellular nuclear antigen 1, SULFATE ION
Authors:Strzalka, W, Oyama, T, Tori, K, Morikawa, K.
Deposit date:2008-11-21
Release date:2009-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment
Protein Sci., 18, 2009
2ZVM
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BU of 2zvm by Molmil
Crystal structure of PCNA in complex with DNA polymerase iota fragment
Descriptor: DNA polymerase iota, Proliferating cell nuclear antigen
Authors:Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M.
Deposit date:2008-11-11
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
J.Biol.Chem., 284, 2009
2ZVW
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BU of 2zvw by Molmil
Crystal structure of Proliferating cell nuclear antigen 2 and Short peptide from human P21
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen 2, SULFATE ION
Authors:Strzalka, W, Oyama, T, Tori, K, Morikawa, K.
Deposit date:2008-11-21
Release date:2009-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of the Arabidopsis thaliana proliferating cell nuclear antigen 1 and 2 proteins complexed with the human p21 C-terminal segment
Protein Sci., 18, 2009
2ZVL
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BU of 2zvl by Molmil
Crystal structure of PCNA in complex with DNA polymerase kappa fragment
Descriptor: DNA polymerase kappa, Proliferating cell nuclear antigen, SULFATE ION, ...
Authors:Hishiki, A, Hashimoto, H, Hanafusa, T, Kamei, K, Ohashi, E, Shimizu, T, Ohmori, H, Sato, M.
Deposit date:2008-11-11
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
J.Biol.Chem., 284, 2009
1U7B
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BU of 1u7b by Molmil
Crystal structure of hPCNA bound to residues 331-350 of the flap endonuclease-1 (FEN1)
Descriptor: Proliferating cell nuclear antigen, SRQGSTQGRLDDFFKVTGSL peptide of Flap endonuclease-1
Authors:Bruning, J.B, Shamoo, Y.
Deposit date:2004-08-03
Release date:2004-12-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
Structure, 12, 2004
3A2F
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BU of 3a2f by Molmil
Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex
Descriptor: DNA polymerase, DNA polymerase sliding clamp
Authors:Nishida, H, Ishino, Y, Morikawa, K.
Deposit date:2009-05-15
Release date:2009-11-03
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex
To be Published
3AIZ
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BU of 3aiz by Molmil
Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (P21212)
Descriptor: DNA polymerase sliding clamp B, DNA polymerase sliding clamp C, SULFATE ION
Authors:Kawai, A, Higuchi, S, Miyamoto, S.
Deposit date:2010-05-18
Release date:2011-05-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A novel heterotetrameric structure of the crenarchaeal PCNA2-PCNA3 complex
J.Struct.Biol., 174, 2011
1W60
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BU of 1w60 by Molmil
NATIVE HUMAN PCNA
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.
Deposit date:2004-08-11
Release date:2005-01-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
1VYM
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BU of 1vym by Molmil
NATIVE HUMAN PCNA
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN
Authors:Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.
Deposit date:2004-05-03
Release date:2005-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
1VYJ
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BU of 1vyj by Molmil
Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design
Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK
Authors:Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.D.
Deposit date:2004-04-30
Release date:2005-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design
Proc.Natl.Acad.Sci.USA, 102, 2005
1UL1
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BU of 1ul1 by Molmil
Crystal structure of the human FEN1-PCNA complex
Descriptor: Flap endonuclease-1, MAGNESIUM ION, Proliferating cell nuclear antigen
Authors:Sakurai, S, Kitano, K, Yamaguchi, H, Hamada, K, Okada, K, Fukuda, K, Uchida, M, Ohtsuka, E, Morioka, H, Hakoshima, T.
Deposit date:2003-09-05
Release date:2005-03-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for recruitment of human flap endonuclease 1 to PCNA
EMBO J., 24, 2005
1U76
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BU of 1u76 by Molmil
Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit
Descriptor: KANRQVSITGFFQRK peptide from DNA polymerase delta subunit 3, Proliferating cell nuclear antigen
Authors:Bruning, J.B, Shamoo, Y.
Deposit date:2004-08-02
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
Structure, 12, 2004
3AIX
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BU of 3aix by Molmil
Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (I222)
Descriptor: DNA polymerase sliding clamp B, DNA polymerase sliding clamp C, SULFATE ION
Authors:Kawai, A, Higuchi, S, Miyamoto, S.
Deposit date:2010-05-18
Release date:2011-05-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A novel heterotetrameric structure of the crenarchaeal PCNA2-PCNA3 complex
J.Struct.Biol., 174, 2011
1SXJ
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BU of 1sxj by Molmil
Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ...
Authors:Bowman, G.D, O'Donnell, M, Kuriyan, J.
Deposit date:2004-03-30
Release date:2004-06-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Nature, 429, 2004

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