1NMS
 
 | | Caspase-3 tethered to irreversible inhibitor | | Descriptor: | 5-[4-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-BENZYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID, Caspase-3 | | Authors: | Erlanson, D.A, Lam, J, Wiesmann, C, Luong, T.N, Simmons, R.L, DeLano, W.L, Choong, I.C, Flanagan, W.M, Lee, D, O'Brian, T. | | Deposit date: | 2003-01-10 | | Release date: | 2003-03-11 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | In situ assembly of enzyme inhibitors using extended tethering.
Nat.Biotechnol., 21, 2003
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2KBY
 | | The Tetramerization Domain of Human p73 | | Descriptor: | Tumor protein p73 | | Authors: | Coutandin, D, Ikeya, T, Loehr, F, Guntert, P, Ou, H.D, Doetsch, V. | | Deposit date: | 2008-12-12 | | Release date: | 2009-09-29 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Conformational stability and activity of p73 require a second helix in the tetramerization domain.
Cell Death Differ., 16, 2009
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2P22
 | | Structure of the Yeast ESCRT-I Heterotetramer Core | | Descriptor: | Hypothetical 12.0 kDa protein in ADE3-SER2 intergenic region, Protein SRN2, SULFATE ION, ... | | Authors: | Kostelansky, M.S, Hurley, J.H. | | Deposit date: | 2007-03-06 | | Release date: | 2007-06-05 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer.
Cell(Cambridge,Mass.), 129, 2007
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2O6V
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2QA9
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1EVN
 | | NMR OBSERVATION OF A-TETRAD | | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*T)-3') | | Authors: | Patel, P.K, Koti, A.S.R, Hosur, R.V. | | Deposit date: | 2000-04-20 | | Release date: | 2000-05-22 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR studies on truncated sequences of human telomeric DNA: observation of a novel A-tetrad.
Nucleic Acids Res., 27, 1999
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1EVM
 | | NMR OBSERVATION OF A-TETRAD | | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*T)-3') | | Authors: | Patel, P.K, Koti, A.S.R, Hosur, R.V. | | Deposit date: | 2000-04-20 | | Release date: | 2000-05-22 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR studies on truncated sequences of human telomeric DNA: observation of a novel A-tetrad.
Nucleic Acids Res., 27, 1999
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1EVO
 | | NMR OBSERVATION OF A NOVEL C-TETRAD | | Descriptor: | DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*T)-3') | | Authors: | Patel, P.K, Bhavesh, N.S, Hosur, R.V. | | Deposit date: | 2000-04-20 | | Release date: | 2000-05-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR observation of a novel C-tetrad in the structure of the SV40 repeat sequence GGGCGG.
Biochem.Biophys.Res.Commun., 270, 2000
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1JN2
 | | Crystal Structure of meso-tetrasulphonatophenyl porphyrin complexed with Concanavalin A | | Descriptor: | 5,10,15,20-TETRAKIS(4-SULPFONATOPHENYL)-21H,23H-PORPHINE, CALCIUM ION, Concanavalin-A, ... | | Authors: | Goel, M, Jain, D, Kaur, K.J, Kenoth, R, Maiya, B.G, Swamy, M.J, Salunke, D.M. | | Deposit date: | 2001-07-22 | | Release date: | 2003-07-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Functional equality in the absence of structural similarity: an added dimension to
molecular mimicry
J.Biol.Chem., 276, 2000
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1JA9
 | | Crystal structure of 1,3,6,8-tetrahydroxynaphthalene reductase in complex with NADPH and pyroquilon | | Descriptor: | 1,3,6,8-tetrahydroxynaphthalene reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYROQUILON | | Authors: | Liao, D.-I, Thompson, J.E, Fahnestock, S, Valent, B, Jordan, D.B. | | Deposit date: | 2001-05-30 | | Release date: | 2001-09-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A structural account of substrate and inhibitor specificity differences between two naphthol reductases.
Biochemistry, 40, 2001
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1Z7J
 | | Human transthyretin (also called prealbumin) complex with 3, 3',5,5'-tetraiodothyroacetic acid (t4ac) | | Descriptor: | 3,3',5,5'-TETRAIODOTHYROACETIC ACID, Transthyretin | | Authors: | Neumann, P, Wojtczak, A, Cody, V. | | Deposit date: | 2005-03-25 | | Release date: | 2005-06-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution.
Acta Crystallogr.,Sect.D, 61, 2005
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1NME
 | | Structure of Casp-3 with tethered salicylate | | Descriptor: | 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID, 3-(2-MERCAPTO-ACETYLAMINO)-4-OXO-PENTANOIC ACID, Caspase-3 | | Authors: | Erlanson, D.A, Lam, J, Wiesmann, C, Luong, T.N, Simmons, B, DeLano, W, Choong, I.C, Flanagan, M, Lee, D, O'Brian, T. | | Deposit date: | 2003-01-09 | | Release date: | 2003-03-11 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | In situ assembly of enzyme inhibitors using extended tethering.
Nat.Biotechnol., 21, 2003
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1EMQ
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244D
 | | THE HIGH-RESOLUTION CRYSTAL STRUCTURE OF A PARALLEL-STRANDED GUANINE TETRAPLEX | | Descriptor: | CALCIUM ION, DNA (5'-D(*TP*GP*GP*GP*GP*T)-3'), SODIUM ION | | Authors: | Laughlan, G, Murchie, A.I.H, Norman, D.G, Moore, M.H, Moody, P.C.E, Lilley, D.M.J, Luisi, B. | | Deposit date: | 1995-10-19 | | Release date: | 1996-02-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The high-resolution crystal structure of a parallel-stranded guanine tetraplex.
Science, 265, 1994
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1XOG
 | | N9 Tern Influenza neuraminidase complexed with a 2,5-Disubstituted tetrahydrofuran-5-carboxylic acid | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-2,5-ANHYDRO-3,4-DIDEOXY-4-(METHOXYCARBONYL)PENTONIC ACID, Neuraminidase, ... | | Authors: | Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G. | | Deposit date: | 2004-10-06 | | Release date: | 2005-01-11 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.
Bioorg.Med.Chem.Lett., 15, 2005
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1N0J
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2BFP
 | | Leishmania major pteridine reductase 1 in complex with NADP and tetrahydrobiopterin | | Descriptor: | 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Schuettelkopf, A.W, Hunter, W.N. | | Deposit date: | 2004-12-10 | | Release date: | 2005-08-31 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structures of Leishmania Major Pteridine Reductase Complexes Reveal the Active Site Features Important for Ligand Binding and to Guide Inhibitor Design
J.Mol.Biol., 352, 2005
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2BOC
 | | Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs) | | Descriptor: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | | Authors: | Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. | | Deposit date: | 2005-04-09 | | Release date: | 2005-04-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
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1QI6
 | | SECOND APO FORM OF AN NADP DEPENDENT ALDEHYDE DEHYDROGENASE WITH GLU250 SITUATED 3.7 A FROM CYS284 | | Descriptor: | PROTEIN (NADP DEPENDENT NONPHOSPHORYLATING GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), SULFATE ION | | Authors: | Cobessi, D, Tete-Favier, F, Marchal, S, Branlant, G, Aubry, A. | | Deposit date: | 1999-06-02 | | Release date: | 2001-01-10 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
J.Mol.Biol., 300, 2000
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294D
 | | INTERCALATED CYTOSINE MOTIF AND NOVEL ADENINE CLUSTERS IN THE CRYSTAL STRUCTURE OF TETRAHYMENA TELOMERE | | Descriptor: | DNA (5'-D(*AP*AP*CP*CP*CP*C)-3') | | Authors: | Cai, L, Chen, L, Raghavan, S, Ratliff, R, Moyzis, R, Rich, A. | | Deposit date: | 1996-10-30 | | Release date: | 1998-10-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere.
Nucleic Acids Res., 26, 1998
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1QI1
 | | Ternary Complex of an NADP Dependent Aldehyde Dehydrogenase | | Descriptor: | GLYCERALDEHYDE-3-PHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (NADP-DEPENDENT NONPHOSPHORYLATING GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), ... | | Authors: | Cobessi, D, Tete-Favier, F, Marchal, S, Branlant, G, Aubry, A. | | Deposit date: | 1999-06-02 | | Release date: | 2001-01-10 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
J.Mol.Biol., 300, 2000
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1X31
 | | Crystal Structure of Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96 | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, N,N-DIMETHYLGLYCINE, ... | | Authors: | Ida, K, Moriguchi, T, Suzuki, H. | | Deposit date: | 2005-04-27 | | Release date: | 2005-07-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96
BIOCHEM.BIOPHYS.RES.COMMUN., 333, 2005
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2BOB
 | | Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA) | | Descriptor: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... | | Authors: | Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. | | Deposit date: | 2005-04-09 | | Release date: | 2005-04-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
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1TAF
 | | DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER | | Descriptor: | TFIID TBP ASSOCIATED FACTOR 42, TFIID TBP ASSOCIATED FACTOR 62, ZINC ION | | Authors: | Xie, X, Kokubo, T, Cohen, S.L, Mirza, U.A, Hoffmann, A, Chait, B.T, Roeder, R.G, Nakatani, Y, Burley, S.K. | | Deposit date: | 1996-06-01 | | Release date: | 1996-12-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural similarity between TAFs and the heterotetrameric core of the histone octamer.
Nature, 380, 1996
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1EM0
 | | COMPLEX OF D(CCTAGG) WITH TETRA-[N-METHYL-PYRIDYL] PORPHYRIN | | Descriptor: | DNA (5'-D(*(CBR)P*CP*TP*AP*GP*G)-3'), MAGNESIUM ION, TETRA[N-METHYL-PYRIDYL] PORPHYRIN-NICKEL | | Authors: | Neidle, S, Sanderson, M, Bennett, M, Krah, A, Wien, F, Garman, E, McKenna, R. | | Deposit date: | 2000-03-14 | | Release date: | 2000-08-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (0.9 Å) | | Cite: | A DNA-porphyrin minor-groove complex at atomic resolution: the structural consequences of porphyrin ruffling.
Proc.Natl.Acad.Sci.USA, 97, 2000
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