2P22

Structure of the Yeast ESCRT-I Heterotetramer Core

Summary for 2P22

Entry DOI	10.2210/pdb2p22/pdb
Related	1UZX 2CAZ 2F66 2F6M 2J9U 2J9V
Descriptor	Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, Vacuolar protein sorting-associated protein 28, Protein SRN2, ... (6 entities in total)
Functional Keywords	endosome, trafficking complex, vps23, vps28, vps37, mvb12, vacuolar protein sorting, escrt protein complexes, endosomal sorting complex required for transport, escrt-i, ubiquitin, tsg101, transport protein
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	4
Total formula weight	66302.47
Authors	Kostelansky, M.S.,Hurley, J.H. (deposition date: 2007-03-06, release date: 2007-06-05, Last modification date: 2024-02-21)
Primary citation	Kostelansky, M.S.,Schluter, C.,Tam, Y.Y.,Lee, S.,Ghirlando, R.,Beach, B.,Conibear, E.,Hurley, J.H. Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell(Cambridge,Mass.), 129:485-498, 2007 Cited by PubMed: 17442384 DOI: 10.1016/j.cell.2007.03.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation