2P22

Structure of the Yeast ESCRT-I Heterotetramer Core

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000813	cellular_component	ESCRT I complex
B	0032509	biological_process	endosome transport via multivesicular body sorting pathway
C	0000813	cellular_component	ESCRT I complex
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005768	cellular_component	endosome
C	0006612	biological_process	protein targeting to membrane
C	0006623	biological_process	protein targeting to vacuole
C	0006886	biological_process	intracellular protein transport
C	0007034	biological_process	vacuolar transport
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0031902	cellular_component	late endosome membrane
C	0032509	biological_process	endosome transport via multivesicular body sorting pathway
C	0043162	biological_process	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
C	0072666	biological_process	establishment of protein localization to vacuole
C	1904669	biological_process	ATP export
D	0000813	cellular_component	ESCRT I complex
D	0032509	biological_process	endosome transport via multivesicular body sorting pathway
D	0043130	molecular_function	ubiquitin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 214

Chain	Residue
C	HIS71
C	HIS73
C	GLN74

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 215

Chain	Residue
A	TYR336
C	HOH21
C	HIS196
C	ARG199
D	GLU6

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 103

Chain	Residue
D	PRO38
D	ALA39
D	LEU40
D	GLN41
D	HOH104
C	LYS113

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 216

Chain	Residue
C	SER22
C	ARG23
C	HIS73
D	ALA39

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