2P22
Structure of the Yeast ESCRT-I Heterotetramer Core
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0000813 | cellular_component | ESCRT I complex |
| B | 0032509 | biological_process | endosome transport via multivesicular body sorting pathway |
| C | 0000813 | cellular_component | ESCRT I complex |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005768 | cellular_component | endosome |
| C | 0006612 | biological_process | protein targeting to membrane |
| C | 0006623 | biological_process | protein targeting to vacuole |
| C | 0006886 | biological_process | intracellular protein transport |
| C | 0015031 | biological_process | protein transport |
| C | 0031902 | cellular_component | late endosome membrane |
| C | 0032509 | biological_process | endosome transport via multivesicular body sorting pathway |
| C | 0043162 | biological_process | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
| C | 0072665 | biological_process | protein localization to vacuole |
| C | 0072666 | biological_process | establishment of protein localization to vacuole |
| C | 1904669 | biological_process | ATP export |
| D | 0000813 | cellular_component | ESCRT I complex |
| D | 0032509 | biological_process | endosome transport via multivesicular body sorting pathway |
| D | 0043130 | molecular_function | ubiquitin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 214 |
| Chain | Residue |
| C | HIS71 |
| C | HIS73 |
| C | GLN74 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 215 |
| Chain | Residue |
| A | TYR336 |
| C | HOH21 |
| C | HIS196 |
| C | ARG199 |
| D | GLU6 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 103 |
| Chain | Residue |
| D | PRO38 |
| D | ALA39 |
| D | LEU40 |
| D | GLN41 |
| D | HOH104 |
| C | LYS113 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 216 |
| Chain | Residue |
| C | SER22 |
| C | ARG23 |
| C | HIS73 |
| D | ALA39 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 63 |
| Details | Domain: {"description":"SB","evidences":[{"source":"PROSITE-ProRule","id":"PRU00644","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 85 |
| Details | Domain: {"description":"VPS37 C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00646","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
