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6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Wieland, M, Wilson, D.N.
Deposit date:2020-02-26
Release date:2020-07-01
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
7NKE
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BU of 7nke by Molmil
Crystal structure of human RXRalpha ligand binding domain in complex with 2,4-di-tert-butylphenol and a coactivator fragment
Descriptor: 2,4-di~{tert}-butylphenol, FORMIC ACID, Nuclear receptor coactivator 2, ...
Authors:Carivenc, C, Bourguet, W.
Deposit date:2021-02-17
Release date:2022-03-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors.
Endocrinology, 164, 2023
1N9A
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BU of 1n9a by Molmil
Farnesyltransferase complex with tetrahydropyridine inhibitors
Descriptor: 1-{2-[3-(4-CYANO-BENZYL)-3H-IMIDAZOL-4-YL]-ACETYL}-5-NAPHTHALEN-1-YL-1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ...
Authors:Gwaltney II, S.L, O'Conner, S.J, Nelson, L.T, Sullivan, G.M, Imade, H, Wang, W, Hasvold, L, Li, Q, Cohen, J, Gu, W.Z.
Deposit date:2002-11-22
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency.
Bioorg.Med.Chem.Lett., 13, 2003
2FPO
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BU of 2fpo by Molmil
Putative methyltransferase yhhF from Escherichia coli.
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, methylase yhhF
Authors:Osipiuk, J, Kim, Y, Sanishvili, R, Skarina, T, Evdokimova, E, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-01-16
Release date:2006-02-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure.
J.Biol.Chem., 282, 2007
2FR4
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BU of 2fr4 by Molmil
Structure of Fab DNA-1 complexed with a stem-loop DNA ligand
Descriptor: 5'-D(*CP*TP*GP*CP*CP*TP*TP*CP*AP*G)-3', TETRAETHYLENE GLYCOL, antibody heavy chain FAB, ...
Authors:Tanner, J.J, Ou, Z.
Deposit date:2006-01-18
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Impact of DNA hairpin folding energetics on antibody-ssDNA association.
J.Mol.Biol., 374, 2007
6XZU
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BU of 6xzu by Molmil
Complex of C-terminal domain of murine complement C3b with the hC3Nb3 nanobody
Descriptor: Complement C3, nanobody hC3Nb1
Authors:Andersen, G.R, Pedersen, H.
Deposit date:2020-02-05
Release date:2020-08-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
J Immunol., 205, 2020
1O6D
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BU of 1o6d by Molmil
Crystal structure of a hypothetical protein
Descriptor: Hypothetical UPF0247 protein TM0844
Authors:Structural GenomiX
Deposit date:2003-11-03
Release date:2003-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
1OBC
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BU of 1obc by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A POST-TRANSFER EDITING SUBSTRATE ANALOGUE
Descriptor: 2'-AMINO-2'-DEOXYADENOSINE, LEUCINE, LEUCYL-TRNA SYNTHETASE, ...
Authors:Cusack, S, Yaremchuk, A, Tukalo, M.
Deposit date:2003-01-30
Release date:2003-05-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Basis of Pre- and Posttransfer Editing by Leucyl-tRNA Synthetase
Mol.Cell, 11, 2003
1ARG
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BU of 1arg by Molmil
Aspartate aminotransferase, phospho-5'-pyridoxyl aspartate complex
Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE
Authors:Malashkevich, V.N, Jansonius, J.N.
Deposit date:1995-08-23
Release date:1995-11-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme.
Eur.J.Biochem., 232, 1995
1O69
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BU of 1o69 by Molmil
Crystal structure of a PLP-dependent enzyme
Descriptor: (2-AMINO-4-FORMYL-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, BETA-MERCAPTOETHANOL, aminotransferase
Authors:Structural GenomiX
Deposit date:2003-10-23
Release date:2003-11-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
6VU5
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BU of 6vu5 by Molmil
Structure of G-alpha-q bound to its chaperone Ric-8A
Descriptor: Guanine nucleotide-binding protein G(q) subunit alpha, Resistance to inhibitors of cholinesterase-8A (Ric-8A)
Authors:Seven, A.B, Hilger, D.
Deposit date:2020-02-14
Release date:2020-03-18
Last modified:2020-03-25
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of G alpha Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.
Cell Rep, 30, 2020
2IFC
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BU of 2ifc by Molmil
The Structure of the Binary Complex of Oxalateacetate with Citrate Synthase from the Thermophilic Archaeon Thermolasma acidophilum
Descriptor: Citrate Synthase, OXALOACETATE ION
Authors:Lehmann, C.
Deposit date:2006-09-20
Release date:2007-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:To be anounced
To be Published
2IGK
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BU of 2igk by Molmil
Crystal structure of recombinant pyranose 2-oxidase
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose oxidase
Authors:Divne, C.
Deposit date:2006-09-22
Release date:2006-10-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for substrate binding and regioselective oxidation of monosaccharides at c3 by pyranose 2-oxidase.
J.Biol.Chem., 281, 2006
1BRI
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BU of 1bri by Molmil
BARNASE MUTANT WITH ILE 76 REPLACED BY ALA
Descriptor: BARNASE
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
7OCZ
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BU of 7ocz by Molmil
Crystal Structure of the PID-3 RRM domain
Descriptor: CHLORIDE ION, Protein pid-3
Authors:Basquin, J, Ketting, R.F, Falk, S.
Deposit date:2021-04-28
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans .
Genes Dev., 35, 2021
7O6N
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BU of 7o6n by Molmil
Crystal structure of C. elegans ERH-2 PID-3 complex
Descriptor: Enhancer of rudimentary homolog 2, FORMIC ACID, Protein pid-3
Authors:Falk, S, Ketting, R.F.
Deposit date:2021-04-11
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans .
Genes Dev., 35, 2021
7OCX
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BU of 7ocx by Molmil
Crystal Structure of the PID-3 TOFU-6 RRM domain complex
Descriptor: Embryonic developmental protein tofu-6, Protein pid-3
Authors:Basquin, J, Ketting, R.F, Falk, S.
Deposit date:2021-04-28
Release date:2021-08-25
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans .
Genes Dev., 35, 2021
7O6L
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BU of 7o6l by Molmil
Crystal structure of C. elegans ERH-2
Descriptor: Enhancer of rudimentary homolog 2
Authors:Falk, S, Ketting, R.F.
Deposit date:2021-04-11
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans .
Genes Dev., 35, 2021
7NPI
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BU of 7npi by Molmil
Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5)
Descriptor: CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ...
Authors:Lange, S.M, Armstrong, L.A, Kulathu, Y.
Deposit date:2021-02-26
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.
Mol.Cell, 81, 2021
6Y8F
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BU of 6y8f by Molmil
An inactive (D136N and D137N) variant of alpha-1,6-mannanase, GH76A of Salegentibacter sp. HEL1_6 in complex with alpha-1,6-mannotriose
Descriptor: Alpha-1,6-endo-mannanase GH76A mutant, CALCIUM ION, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose
Authors:Hehemann, J.H, Solanki, V.A.
Deposit date:2020-03-04
Release date:2021-03-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.472 Å)
Cite:Glycoside hydrolase from the GH76 family indicates that marine Salegentibacter sp. Hel_I_6 consumes alpha-mannan from fungi.
Isme J, 2022
1BU8
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BU of 1bu8 by Molmil
RAT PANCREATIC LIPASE RELATED PROTEIN 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (PANCREATIC LIPASE RELATED PROTEIN 2)
Authors:Roussel, A, Cambillau, C.
Deposit date:1998-09-14
Release date:1998-12-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and activity of rat pancreatic lipase-related protein 2.
J.Biol.Chem., 273, 1998
2IGW
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BU of 2igw by Molmil
CYCLOPHILIN 3 complexed with DIPEPTIDE GLY-PRO
Descriptor: GLYCINE, PROLINE, Peptidyl-prolyl cis-trans isomerase 3
Authors:Kan, D.
Deposit date:2006-09-25
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Experimental Determination of van der Waals Energies in a Biological System.
Angew.Chem.Int.Ed.Engl., 46, 2007
1OFD
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BU of 1ofd by Molmil
Glutamate Synthase from Synechocystis sp in complex with 2-Oxoglutarate at 2.0 Angstrom resolution
Descriptor: 2-OXOGLUTARIC ACID, FE3-S4 CLUSTER, FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE 2, ...
Authors:Van Den heuvel, R.H.H, Mattevi, A.
Deposit date:2003-04-14
Release date:2003-06-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Active Conformation of Glutamate Synthase and its Binding to Ferredoxin
J.Mol.Biol., 330, 2003
7NUS
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BU of 7nus by Molmil
X-RAY STRUCTURE OF HDM2/CMR19 AT 1.45A: Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, SULFATE ION, ...
Authors:Kallen, J.
Deposit date:2021-03-13
Release date:2021-09-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitors.
Rsc Chem Biol, 2, 2021
1OFF
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BU of 1off by Molmil
2Fe-2S Ferredoxin from Synechocystis sp. PCC 6803
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN I
Authors:Van Den heuvel, R.H.H, Mattevi, A.
Deposit date:2003-04-14
Release date:2003-06-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Active Conformation of Glutamate Synthase and its Binding to Ferredoxin
J.Mol.Biol., 330, 2003

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