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5R9S
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BU of 5r9s by Molmil
PanDDA analysis group deposition Form1 MAP kinase p38-alpha -- Fragment N13470a in complex with MAP kinase p38-alpha
Descriptor: 5-(4-chlorophenyl)furan-2-carbohydrazide, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:De Nicola, G.F, Nichols, C.E.
Deposit date:2020-03-04
Release date:2020-07-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes.
J.Med.Chem., 63, 2020
8BYW
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BU of 8byw by Molmil
Rut B structure
Descriptor: Ureidoacrylate amidohydrolase RutB
Authors:Rajendran, C, Sterner, R, Busch, M.
Deposit date:2022-12-14
Release date:2023-01-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural and Functional Characterization of the Ureidoacrylate Amidohydrolase RutB from Escherichia coli .
Biochemistry, 62, 2023
5HOG
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BU of 5hog by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
Descriptor: DNA polymerase alpha-binding protein, Dna2p
Authors:Simon, A.C, Pellegrini, L.
Deposit date:2016-01-19
Release date:2016-06-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.092 Å)
Cite:Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5HYM
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BU of 5hym by Molmil
3-Hydroxybenzoate 6-hydroxylase from Rhodococcus jostii in complex with phosphatidylinositol
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Phosphatidylinositol, ...
Authors:Orru, R, Montersino, S, Mattevi, A, van Berkel, W.J.H.
Deposit date:2016-02-01
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.
Front Microbiol, 8, 2017
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
1B49
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BU of 1b49 by Molmil
DCMP HYDROXYMETHYLASE FROM T4 (PHOSPHATE-BOUND)
Descriptor: PHOSPHATE ION, PROTEIN (DEOXYCYTIDYLATE HYDROXYMETHYLASE)
Authors:Song, H.K, Sohn, S.H, Suh, S.W.
Deposit date:1999-01-06
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of deoxycytidylate hydroxymethylase from bacteriophage T4, a component of the deoxyribonucleoside triphosphate-synthesizing complex.
EMBO J., 18, 1999
6ER6
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BU of 6er6 by Molmil
Crystal structure of a computationally designed colicin endonuclease and immunity pair colEdes7/Imdes7
Descriptor: Endonuclease colEdes7, immunity Imdes7
Authors:Netzer, R, Listov, D, Dym, O, Albeck, S, Knop, O, Fleishman, S.J.
Deposit date:2017-10-17
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Ultrahigh specificity in a network of computationally designed protein-interaction pairs.
Nat Commun, 9, 2018
6ULC
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BU of 6ulc by Molmil
Structure of full-length, fully glycosylated, non-modified HIV-1 gp160 bound to PG16 Fab at a nominal resolution of 4.6 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Pan, J, Chen, B, Harrison, S.C.
Deposit date:2019-10-07
Release date:2020-04-29
Last modified:2020-09-09
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Cryo-EM Structure of Full-length HIV-1 Env Bound With the Fab of Antibody PG16.
J.Mol.Biol., 432, 2020
5I2Y
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BU of 5i2y by Molmil
Crystal Structure of TPP1 K170A
Descriptor: Adrenocortical dysplasia protein homolog
Authors:Nandakumar, J, Smith, E.M.
Deposit date:2016-02-09
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
5I2X
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BU of 5i2x by Molmil
Crystal Structure of TPP1 K170del
Descriptor: Adrenocortical dysplasia protein homolog
Authors:Nandakumar, J, Smith, E.
Deposit date:2016-02-09
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
8CH6
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BU of 8ch6 by Molmil
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Cretu, C, Schmitzova, J, Pena, V.
Deposit date:2023-02-07
Release date:2023-05-10
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
5IP4
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BU of 5ip4 by Molmil
X-RAY STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin, XA4551 NANOBODY AGAINST C-DCX
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-09
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
3HHR
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BU of 3hhr by Molmil
HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX
Descriptor: HUMAN GROWTH HORMONE, HUMAN GROWTH HORMONE RECEPTOR (hGHbp)
Authors:De Vos, A.M, Ultsch, M, Kossiakoff, A.A.
Deposit date:1993-12-30
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.
Science, 255, 1992
5IO9
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BU of 5io9 by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-08
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
8CHB
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BU of 8chb by Molmil
Inward-facing conformation of the ABC transporter BmrA C436S/A582C cross-linked mutant
Descriptor: Multidrug resistance ABC transporter ATP-binding/permease protein BmrA
Authors:Di Cesare, M, Kaplan, E, Hanssen, E, Valimehr, S, Orelle, C, Jault, J.M.
Deposit date:2023-02-07
Release date:2023-12-20
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
J.Biol.Chem., 300, 2023
9BEZ
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BU of 9bez by Molmil
MID domain of human Argo2 bound to RNA
Descriptor: Protein argonaute-2, [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate
Authors:Harp, J.M, Egli, M.
Deposit date:2024-04-16
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth.
Curr Protoc, 4, 2024
6UBH
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BU of 6ubh by Molmil
Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide
Descriptor: Erbin, SODIUM ION, peptide
Authors:Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S.
Deposit date:2019-09-11
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.
J.Mol.Biol., 433, 2021
5IKC
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BU of 5ikc by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB
Descriptor: CHLORIDE ION, Ighg protein, MAb 6H10 light chain, ...
Authors:Ruf, A, Stihle, M, Benz, J, Thoma, R, Rudolph, M.G.
Deposit date:2016-03-03
Release date:2016-05-18
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
8CD3
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BU of 8cd3 by Molmil
Crystal structure of human Scribble PDZ1 domain in complex with human TMIGD1
Descriptor: Protein scribble homolog, Transmembrane and immunoglobulin domain-containing protein 1
Authors:Maddumage, J.C, Kvansakul, M.
Deposit date:2023-01-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1.
Commun Biol, 6, 2023
6UUQ
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BU of 6uuq by Molmil
Structure of Calcineurin bound to RCAN1
Descriptor: Calcipressin-1, FE (III) ION, PHOSPHATE ION, ...
Authors:Sheftic, S, Page, R, Peti, W.
Deposit date:2019-10-31
Release date:2020-09-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin.
Sci Adv, 6, 2020
5IRR
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BU of 5irr by Molmil
Crystal structure of Septin GTPase domain from Chlamydomonas reinhardtii
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Septin-like protein
Authors:Pinto, A.P.A, Pereira, H.M, Navarro, M.V.A.S, Brandao-Neto, J, Garratt, R.C, Araujo, A.P.U.
Deposit date:2016-03-14
Release date:2017-04-26
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Filaments and fingers: Novel structural aspects of the single septin from Chlamydomonas reinhardtii.
J. Biol. Chem., 292, 2017
8CDT
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BU of 8cdt by Molmil
Crystal structure of the xNup93-Nb2t VHH antibody
Descriptor: 15-Nup93 tracking VHH antibody, GLYCEROL
Authors:Guttler, T, Colom, M.S, Gorlich, D.
Deposit date:2023-02-01
Release date:2024-02-21
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 43, 2024
8CEX
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BU of 8cex by Molmil
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH11227
Descriptor: 6-fluoranyl-N-[(4-methylphenyl)methyl]pyridine-3-carboxamide, N-glycosylase/DNA lyase, NICKEL (II) ION
Authors:Kosenina, S, Scaletti, E.R, Stenmark, P.
Deposit date:2023-02-02
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH11227
To Be Published
5IN7
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BU of 5in7 by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-07
Release date:2016-03-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5I2C
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BU of 5i2c by Molmil
Arginine-bound CASTOR1 from Homo sapiens
Descriptor: ACETATE ION, ARGININE, GATS-like protein 3
Authors:Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2016-02-08
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Nature, 536, 2016

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