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3ZMT
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BU of 3zmt by Molmil
LSD1-CoREST in complex with PRSFLV peptide
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, PEPTIDE, ...
Authors:Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A.
Deposit date:2013-02-12
Release date:2013-06-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase.
Acs Chem.Biol., 8, 2013
6FQQ
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BU of 6fqq by Molmil
Crystal structure of TALE homeobox domain transcription factor TGIF1 double alanine mutant bound to its consensus DNA
Descriptor: CHLORIDE ION, DNA (5'-D(P*AP*TP*TP*GP*AP*CP*AP*GP*CP*TP*GP*TP*CP*AP*AP*T)-3'), Homeobox protein TGIF1
Authors:Guca, E, Macias, M.J.
Deposit date:2018-02-14
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.25000262 Å)
Cite:TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-beta signaling.
Nucleic Acids Res., 46, 2018
2XTD
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BU of 2xtd by Molmil
Structure of the TBL1 tetramerisation domain
Descriptor: TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
6GZ1
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BU of 6gz1 by Molmil
Crystal Structure of the LeuO Effector Binding Domain
Descriptor: HTH-type transcriptional regulator LeuO, SULFATE ION
Authors:Fragel, S, Montada, A.M, Baumann, U, Schacherl, M, Schnetz, K.
Deposit date:2018-07-02
Release date:2019-06-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Characterization of the pleiotropic LysR-type transcription regulator LeuO of Escherichia coli.
Nucleic Acids Res., 47, 2019
2VXF
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BU of 2vxf by Molmil
Solution structure of the LSm-domain of zebrafish RAP55
Descriptor: LSM14A PROTEIN
Authors:Tritschler, F, Coles, M, Truffault, V.
Deposit date:2008-07-03
Release date:2008-09-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes.
Mol. Cell. Biol., 28, 2008
2IZ8
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BU of 2iz8 by Molmil
MS2-RNA HAIRPIN (C-7) COMPLEX
Descriptor: MS2 COAT PROTEIN, RNA, (5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*CP*UP*CP* AP*CP*CP*CP*AP*UP*GP*U)-3')
Authors:Helgstrand, C, Grahn, E, Stonehouse, N.J, Stockley, P.G, Liljas, L.
Deposit date:2006-07-25
Release date:2006-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Investigating the Structural Basis of Purine Specificity in the Structures of MS2 Coat Protein RNA Translational Operator Hairpins
Nucleic Acids Res., 30, 2002
3PXP
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BU of 3pxp by Molmil
Crystal structure of a PAS and DNA binding domain containing protein (Caur_2278) from CHLOROFLEXUS AURANTIACUS J-10-FL at 2.30 A resolution
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Helix-turn-helix domain protein, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2010-12-10
Release date:2011-01-19
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of an MmyB-Like Regulator from C. aurantiacus, Member of a New Transcription Factor Family Linked to Antibiotic Metabolism in Actinomycetes.
Plos One, 7, 2012
6TBT
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BU of 6tbt by Molmil
Crystal structure of the BCL6 BTB domain in complex with an Apt48 peptide
Descriptor: Apt48 peptide, B-cell lymphoma 6 protein, CHLORIDE ION, ...
Authors:Zacharchenko, T, Wright, S.C.
Deposit date:2019-11-04
Release date:2021-10-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural basis of Apt48 inhibition of the BCL6 BTB domain.
Structure, 2021
6TCJ
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BU of 6tcj by Molmil
Crystal structure of the BCL6 BTB domain in complex with a hybrid BTB-binding (HBP) peptide
Descriptor: B-cell lymphoma 6 protein, Hybrid BTB-binding (HBP) peptide, SODIUM ION
Authors:Zacharchenko, T, Wright, S.C.
Deposit date:2019-11-06
Release date:2021-10-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of Apt48 inhibition of the BCL6 BTB domain.
Structure, 2021
3K33
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BU of 3k33 by Molmil
Crystal structure of the Phd-Doc complex
Descriptor: ACETATE ION, Death on curing protein, Polypeptide of unknown amino acids and source, ...
Authors:Loris, R, Garcia-Pino, A.
Deposit date:2009-10-01
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity.
Cell(Cambridge,Mass.), 142, 2010
4JG3
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BU of 4jg3 by Molmil
Crystal structure of catabolite repression control protein (crc) from Pseudomonas aeruginosa
Descriptor: CHLORIDE ION, Catabolite repression control protein
Authors:Grishkovskaya, I, Milojevic, T, Sonnleitner, E, Blaesi, U, Djinovic-Carugo, K.
Deposit date:2013-02-28
Release date:2013-06-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Pseudomonas aeruginosa Catabolite Repression Control Protein Crc Is Devoid of RNA Binding Activity
Plos One, 8, 2013
3MW6
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BU of 3mw6 by Molmil
Crystal structure of NMB1681 from Neisseria meningitidis MC58, a FinO-like RNA chaperone
Descriptor: GLYCEROL, uncharacterized protein NMB1681
Authors:Tan, K, Zhou, M, Duggan, E, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-05
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:N. meningitidis 1681 is a member of the FinO family of RNA chaperones.
Rna Biol., 7, 2010
4LZL
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BU of 4lzl by Molmil
Structure of the inactive form of the regulatory domain from the repressor of iron transport regulator (RitR)
Descriptor: GLYCEROL, Response regulator
Authors:Silvaggi, N.R, Han, L, Ulijasz, A.T.
Deposit date:2013-07-31
Release date:2014-09-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Defining the Aspartate-Less Receiver (ALR) Domains: Structure and Activation of RitR from Streptococcus pneumoniae
To be Published
5EY0
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BU of 5ey0 by Molmil
Crystal structure of CodY from Staphylococcus aureus with GTP and Ile
Descriptor: GTP-sensing transcriptional pleiotropic repressor CodY, GUANOSINE-5'-TRIPHOSPHATE, ISOLEUCINE
Authors:Han, A, Hwang, K.Y.
Deposit date:2015-11-24
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
5X60
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BU of 5x60 by Molmil
Crystal structure of LSD1-CoREST in complex with peptide 9
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ...
Authors:Kikuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T.
Deposit date:2017-02-20
Release date:2017-04-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017
5EY1
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BU of 5ey1 by Molmil
Crystal structure of CodY from Staphylococcus aureus with GTP and Ile
Descriptor: GTP-sensing transcriptional pleiotropic repressor CodY, GUANOSINE-5'-TRIPHOSPHATE, ISOLEUCINE
Authors:Han, A, Hwang, K.Y.
Deposit date:2015-11-24
Release date:2016-09-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
7B22
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BU of 7b22 by Molmil
Vibrio cholerae ParD2 Antitoxin
Descriptor: Antitoxin ParD
Authors:Garcia-Rodriguez, G, Loris, R.
Deposit date:2020-11-25
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Entropic pressure controls the oligomerization of the Vibrio cholerae ParD2 antitoxin.
Acta Crystallogr D Struct Biol, 77, 2021
3HTH
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BU of 3hth by Molmil
Crystal structure of multidrug binding protein EbrR complexed with proflavin
Descriptor: EbrA repressor, NICKEL (II) ION, PROFLAVIN
Authors:Dong, J, Ni, L, Schumacher, M, Brennan, R.
Deposit date:2009-06-11
Release date:2010-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
3C2I
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BU of 3c2i by Molmil
The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF
Descriptor: DNA (5'-D(*DAP*DTP*DAP*DGP*DAP*DAP*DGP*DAP*DAP*DTP*DTP*DCP*(5CM)P*DGP*DTP*DTP*DCP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DCP*DTP*DGP*DGP*DAP*DAP*(5CM)P*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DTP*DA)-3'), Methyl-CpG-binding protein 2
Authors:Ho, K.L, McNae, I.W, Schmiedeberg, L, Klose, R.J, Bird, A.P, Walkinshaw, M.D.
Deposit date:2008-01-25
Release date:2008-05-13
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MeCP2 binding to DNA depends upon hydration at methyl-CpG
Mol.Cell, 29, 2008
3HTA
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BU of 3hta by Molmil
Crystal structure of multidrug binding protein EbrR complexed with imidazole
Descriptor: EbrA repressor, IMIDAZOLE
Authors:Dong, J, Ni, L, Schumacher, M, Brennan, R.
Deposit date:2009-06-11
Release date:2010-07-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
2W1T
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BU of 2w1t by Molmil
Crystal Structure of B. subtilis SpoVT
Descriptor: STAGE V SPORULATION PROTEIN T
Authors:Asen, I, Djuranovic, S, Lupas, A.N, Zeth, K.
Deposit date:2008-10-20
Release date:2008-11-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Spovt, the Final Modulator of Gene Expression During Spore Development in Bacillus Subtilis
J.Mol.Biol., 386, 2009
3QPH
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BU of 3qph by Molmil
The three-dimensional structure of TrmB, a global transcriptional regulator of the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose
Descriptor: ACETATE ION, GLYCEROL, TrmB, ...
Authors:Krug, M, Lee, S.-J, Boos, W, Welte, W, Diederichs, K.
Deposit date:2011-02-13
Release date:2012-05-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.992 Å)
Cite:The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose.
Protein Sci., 22, 2013
3HTJ
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BU of 3htj by Molmil
Crystal structure of multidrug binding protein EbrR complexed with ethidium
Descriptor: ETHIDIUM, EbrA repressor, NICKEL (II) ION
Authors:Dong, J, Ni, L, Schumacher, M, Brennan, R.
Deposit date:2009-06-11
Release date:2010-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity is key to multiple ligand binding by the multidrug binding regulator EbrR
To be Published
5U8K
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BU of 5u8k by Molmil
RitR mutant - C128S
Descriptor: Response regulator
Authors:Silvaggi, N.R, Han, L.
Deposit date:2016-12-14
Release date:2017-12-20
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
2F3X
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BU of 2f3x by Molmil
Crystal structure of FapR (in complex with effector)- a global regulator of fatty acid biosynthesis in B. subtilis
Descriptor: MALONYL-COENZYME A, Transcription factor fapR
Authors:Buschiazzo, A, Guerin, M.E, Alzari, P.M.
Deposit date:2005-11-22
Release date:2006-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of lipid biosynthesis regulation in Gram-positive bacteria.
Embo J., 25, 2006

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