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2FJI
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Crystal structure of the C-terminal domain of the exocyst subunit Sec6p
Descriptor: Exocyst complex component SEC6
Authors:Sivaram, M.V, Munson, M.
Deposit date:2006-01-02
Release date:2006-05-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles.
Nat.Struct.Mol.Biol., 13, 2006
2QFN
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X-ray Crystal Structure Analysis of the Binding Site in the Ferric and Oxyferrous Forms of the Recombinant Heme Dehaloperoxidase Cloned from Amphitrite ornata
Descriptor: AMMONIUM ION, Dehaloperoxidase A, OXYGEN MOLECULE, ...
Authors:de Serrano, V, Chen, Z, Davis, M.F, Franzen, S.
Deposit date:2007-06-27
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:X-ray crystal structural analysis of the binding site in the ferric and oxyferrous forms of the recombinant heme dehaloperoxidase cloned from Amphitrite ornata
Acta Crystallogr.,Sect.D, 63, 2007
2QHL
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BU of 2qhl by Molmil
Crystal Structure of Novel Immune-Type Receptor 10 Extracellular Fragment from Ictalurus punctatus
Descriptor: Novel immune-type receptor 10
Authors:Ostrov, D.A, Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Magis, A.T, Bailey, K.M, Litman, G.W.
Deposit date:2007-07-02
Release date:2008-06-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:A bony fish immunological receptor of the NITR multigene family mediates allogeneic recognition.
Immunity, 29, 2008
2F1M
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BU of 2f1m by Molmil
Conformational flexibility in the multidrug efflux system protein AcrA
Descriptor: Acriflavine resistance protein A
Authors:Mikolosko, J, Bobyk, K, Zgurskaya, H.I, Ghosh, P.
Deposit date:2005-11-14
Release date:2006-03-21
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Conformational Flexibility in the Multidrug Efflux System Protein AcrA.
Structure, 14, 2006
2QJX
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Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1
Descriptor: Protein BIM1
Authors:Slep, K.C, Vale, R.D.
Deposit date:2007-07-09
Release date:2007-10-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170, and EB1.
Mol.Cell, 27, 2007
2QJZ
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Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1
Descriptor: Microtubule-associated protein RP/EB family member 1
Authors:Slep, K.C, Vale, R.D.
Deposit date:2007-07-09
Release date:2007-10-02
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170, and EB1.
Mol.Cell, 27, 2007
2F6P
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BU of 2f6p by Molmil
BenM effector binding domain- SeMet derivative
Descriptor: ACETATE ION, HTH-type transcriptional regulator benM, SODIUM ION, ...
Authors:Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C.
Deposit date:2005-11-29
Release date:2006-10-31
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator.
J.Mol.Biol., 367, 2007
2QNJ
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BU of 2qnj by Molmil
Kinase and Ubiquitin-associated domains of MARK3/Par-1
Descriptor: MAP/microtubule affinity-regulating kinase 3
Authors:Murphy, J.M, Ceccarelli, D.F.J, Sicheri, F, Pawson, T.
Deposit date:2007-07-18
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QO9
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Human EphA3 kinase and juxtamembrane region, phosphorylated, AMP-PNP bound
Descriptor: Ephrin receptor, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2007-07-20
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3).
Structure, 16, 2008
2QPA
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Crystal Structure of S.cerevisiae Vps4 in the presence of ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Vacuolar protein sorting-associated protein 4
Authors:Xiao, J, Xu, Z.
Deposit date:2007-07-23
Release date:2007-10-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural characterization of the ATPase reaction cycle of endosomal AAA protein Vps4.
J.Mol.Biol., 374, 2007
2FB8
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Structure of the B-Raf kinase domain bound to SB-590885
Descriptor: (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, B-Raf proto-oncogene serine/threonine-protein kinase
Authors:Lougheed, J.C, Lee, J, Chau, D.C, Stout, T.J.
Deposit date:2005-12-08
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
Cancer Res., 66, 2006
2QQI
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Crystal Structure of the b1b2 Domains from Human Neuropilin-1
Descriptor: GLYCEROL, Neuropilin-1
Authors:Appleton, B.A, Desmarais, W, Wiesmann, C.
Deposit date:2007-07-26
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QRK
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BU of 2qrk by Molmil
Crystal Structure of AMP-bound Saccharopine Dehydrogenase (L-Lys Forming) from Saccharomyces cerevisiae
Descriptor: ADENOSINE MONOPHOSPHATE, Saccharopine dehydrogenase [NAD+, L-lysine-forming
Authors:Andi, B, Xu, H, Cook, P.F, West, A.H.
Deposit date:2007-07-28
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structures of Ligand-Bound Saccharopine Dehydrogenase from Saccharomyces cerevisiae
Biochemistry, 46, 2007
2QR0
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BU of 2qr0 by Molmil
Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs
Descriptor: Fab-Fragment Heavy Chain, Fab-Fragment Light Chain, Vascular endothelial growth factor A
Authors:Wiesmann, C.
Deposit date:2007-07-27
Release date:2007-08-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries
J.Mol.Biol., 373, 2007
2QV3
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BU of 2qv3 by Molmil
Crystal Structure of the Helicobacter pylori Vacuolating Toxin p55 Domain
Descriptor: Vacuolating cytotoxin
Authors:Gangwer, K.A.
Deposit date:2007-08-07
Release date:2007-10-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QXL
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BU of 2qxl by Molmil
Crystal Structure Analysis of Sse1, a yeast Hsp110
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein homolog SSE1, MAGNESIUM ION, ...
Authors:Hendrickson, W.A, Liu, Q.
Deposit date:2007-08-12
Release date:2007-10-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Insights into hsp70 chaperone activity from a crystal structure of the yeast hsp110 Sse1.
Cell(Cambridge,Mass.), 131, 2007
2NQA
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BU of 2nqa by Molmil
Catalytic Domain of Human Calpain 8
Descriptor: CALCIUM ION, Calpain-8, Leupeptin Inhibitor
Authors:Davis, T.L, Paramanathan, R, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-10-30
Release date:2006-11-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Human Calpain 8
To be Published
2NPT
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Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox)
Descriptor: Dual specificity mitogen-activated protein kinase kinase 5, Mitogen-activated protein kinase kinase kinase 2
Authors:Filippakopoulos, P, Debreczeni, J, Papagrigoriou, V, Turnbull, A, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2006-10-30
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of the complex of human mitogen activated protein kinase kinase 5 phox domain (MAP2K5-phox) with human mitogen activated protein kinase kinase kinase 2 phox domain (MAP3K2-phox)
To be Published
2NO4
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Crystal Structure analysis of a Dehalogenase
Descriptor: (S)-2-haloacid dehalogenase IVA, CHLORIDE ION, SULFATE ION
Authors:Schmidberger, J.W, Wilce, M.C.J.
Deposit date:2006-10-24
Release date:2007-09-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structures of the substrate free-enzyme, and reaction intermediate of the HAD superfamily member, haloacid dehalogenase DehIVa from Burkholderia cepacia MBA4
J.Mol.Biol., 368, 2007
2NLK
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BU of 2nlk by Molmil
Crystal structure of D1 and D2 catalytic domains of human Protein Tyrosine Phosphatase Gamma (D1+D2 PTPRG)
Descriptor: Protein tyrosine phosphatase, receptor type, G variant (Fragment)
Authors:Filippakopoulos, P, Gileadi, O, Johansson, C, Ugochukwu, E, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2006-10-20
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2R18
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BU of 2r18 by Molmil
Structural insights into the multifunctional protein VP3 of Birnaviruses
Descriptor: Capsid assembly protein VP3
Authors:Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N.
Deposit date:2007-08-22
Release date:2008-02-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure, 16, 2008
2R4U
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BU of 2r4u by Molmil
Crystal Structure of Wild-type E.coli GS in complex with ADP and Glucose(wtGSd)
Descriptor: (2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Sheng, F, Geiger, J.
Deposit date:2007-09-01
Release date:2008-09-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.367 Å)
Cite:The crystal structures of the open and catalytically competent closed conformation of Escherichia coli glycogen synthase.
J.Biol.Chem., 284, 2009
2R45
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BU of 2r45 by Molmil
Crystal structure of Escherichia coli Glycerol-3-phosphate Dehydrogenase in complex with 2-phospho-d-glyceric acid
Descriptor: 1,2-ETHANEDIOL, 2-PHOSPHOGLYCERIC ACID, Aerobic glycerol-3-phosphate dehydrogenase, ...
Authors:Yeh, J.I, Du, S, Chinte, U.
Deposit date:2007-08-30
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism
Proc.Natl.Acad.Sci.USA, 105, 2008
2QAP
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BU of 2qap by Molmil
Fructose-1,6-bisphosphate aldolase from Leishmania mexicana
Descriptor: Fructose-1,6-bisphosphate aldolase, PHOSPHATE ION
Authors:Lafrance-Vanasse, J, Sygusch, J.
Deposit date:2007-06-15
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Carboxy-Terminus Recruitment Induced by Substrate Binding in Eukaryotic Fructose Bis-phosphate Aldolases
Biochemistry, 46, 2007
2QCP
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1.0 A Structure of CusF-Ag(I) residues 10-88 from Escherichia coli
Descriptor: Cation efflux system protein cusF, NITRATE ION, SILVER ION, ...
Authors:Loftin, I.R.
Deposit date:2007-06-19
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:Unusual Cu(I)/Ag(I) coordination of Escherichia coli CusF as revealed by atomic resolution crystallography and X-ray absorption spectroscopy
Protein Sci., 16, 2007

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