7B5N
| Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1. | Descriptor: | 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ... | Authors: | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2020-12-05 | Release date: | 2021-02-10 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
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7B5R
| Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27 | Descriptor: | Cullin-1, Cyclin-A2, Cyclin-dependent kinase 2, ... | Authors: | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2020-12-07 | Release date: | 2021-02-10 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
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7B5S
| Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 | Descriptor: | Cullin-1, E3 ubiquitin-protein ligase ARIH1, E3 ubiquitin-protein ligase RBX1, ... | Authors: | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2020-12-07 | Release date: | 2021-02-10 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
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7B5L
| Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 | Descriptor: | 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ... | Authors: | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2020-12-04 | Release date: | 2021-02-10 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
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7B5M
| Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2 | Descriptor: | Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... | Authors: | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2020-12-05 | Release date: | 2021-02-17 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
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8HHS
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1OCD
| CYTOCHROME C (OXIDIZED) FROM EQUUS CABALLUS, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | CYTOCHROME C, HEME C | Authors: | Qi, P.X, Beckman, R.A, Wand, A.J. | Deposit date: | 1996-07-03 | Release date: | 1997-06-16 | Last modified: | 2018-03-14 | Method: | SOLUTION NMR | Cite: | Solution structure of horse heart ferricytochrome c and detection of redox-related structural changes by high-resolution 1H NMR. Biochemistry, 35, 1996
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7AOR
| mt-SSU from Trypanosoma cruzi in complex with mt-IF-3. | Descriptor: | 30S Ribosomal protein S17-like protein, AKAP7_NLS domain-containing protein, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | Deposit date: | 2020-10-15 | Release date: | 2021-04-28 | Last modified: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7AIH
| The Large subunit of the Kinetoplastid mitochondrial ribosome | Descriptor: | 50S ribosomal protein L13-like protein, C2H2-type domain-containing protein, L51_S25_CI-B8 domain-containing protein, ... | Authors: | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | Deposit date: | 2020-09-27 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7AM2
| Intermediate assembly of the Large subunit from Leishmania major mitochondrial ribosome | Descriptor: | 50S ribosomal protein L13-like protein, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | Authors: | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | Deposit date: | 2020-10-07 | Release date: | 2021-04-28 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7ANE
| Leishmania Major mitochondrial ribosome | Descriptor: | 30S Ribosomal protein S17-like protein, 50S ribosomal protein L13-like protein, AKAP7_NLS domain-containing protein, ... | Authors: | Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. | Deposit date: | 2020-10-11 | Release date: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
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8T63
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4NX7
| single cryogenic temperature model of DHFR | Descriptor: | BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FOLIC ACID, ... | Authors: | Fenwick, R.B, van den Bedem, H, Fraser, J.S, Wright, P.E. | Deposit date: | 2013-12-08 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR. Proc.Natl.Acad.Sci.USA, 111, 2014
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4GCQ
| Crystal Structure of E. coli OmpF porin in complex with Carbenicillin | Descriptor: | (2S,5R,6R,7R)-6-{[(2R)-2-carboxy-2-phenylacetyl]amino}-7-hydroxy-3,3-dimethyl-4-thia-1-azabicyclo[3.2.0]heptane-2-carbo xylic acid, Outer membrane protein F | Authors: | Ziervogel, B.K, Roux, B. | Deposit date: | 2012-07-30 | Release date: | 2012-12-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Binding of Antibiotics in OmpF Porin. Structure, 21, 2013
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5YE5
| structure of endo-lysosomal TRPML1 channel inserting into nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, mammalian endo-lysosomal TRPML1 channel | Authors: | Yang, M, Gao, N. | Deposit date: | 2017-09-15 | Release date: | 2017-11-15 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism Protein Cell, 8, 2017
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5J1J
| Structure of FleN-AMPPNP complex | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION, ... | Authors: | Jain, D, Chanchal, Banerjee, P. | Deposit date: | 2016-03-29 | Release date: | 2017-03-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | ATP-Induced Structural Remodeling in the Antiactivator FleN Enables Formation of the Functional Dimeric Form Structure, 25, 2017
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8RJC
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5YK1
| The complex structure of Rv3197-AMPPNP from Mycobacterium tuberculosis | Descriptor: | GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable conserved ATP-binding protein ABC transporter, ... | Authors: | Rao, Z.H, Zhang, Q.Q. | Deposit date: | 2017-10-11 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. Protein Cell, 9, 2018
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5JPW
| Molecular basis for protein recognition specificity of the DYNLT1/Tctex1 canonical binding groove. Characterization of the interaction with activin receptor IIB | Descriptor: | Dynein light chain Tctex-type 1,Cytoplasmic dynein 1 intermediate chain 2 | Authors: | Rodriguez-Crespo, I, Merino-Gracia, J, Bruix, M, Zamora-Carreras, H. | Deposit date: | 2016-05-04 | Release date: | 2016-08-17 | Last modified: | 2024-07-03 | Method: | SOLUTION NMR | Cite: | Molecular Basis for the Protein Recognition Specificity of the Dynein Light Chain DYNLT1/Tctex1: CHARACTERIZATION OF THE INTERACTION WITH ACTIVIN RECEPTOR IIB. J.Biol.Chem., 291, 2016
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1I6I
| CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION, ... | Authors: | Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. | Deposit date: | 2001-03-02 | Release date: | 2001-05-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Switch-based mechanism of kinesin motors Nature, 411, 2001
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8IO9
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4NX6
| single room temperature model of DHFR | Descriptor: | BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FOLIC ACID, ... | Authors: | Fenwick, R.B, van den Bedem, H, Fraser, J.S, Wright, P.E. | Deposit date: | 2013-12-08 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR. Proc.Natl.Acad.Sci.USA, 111, 2014
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4NW7
| PDE4 catalytic domain | Descriptor: | (4-{[4-(3-chlorophenyl)-6-cyclopropyl-1,3,5-triazin-2-yl]amino}phenyl)acetic acid, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | Authors: | Fox III, D, Edwards, T.E. | Deposit date: | 2013-12-05 | Release date: | 2014-10-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of triazines as selective PDE4B versus PDE4D inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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7BVP
| AdhE spirosome in extended conformation | Descriptor: | Aldehyde-alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | Authors: | Kim, G.J, Song, J.J. | Deposit date: | 2020-04-11 | Release date: | 2020-06-24 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Aldehyde-alcohol dehydrogenase undergoes structural transition to form extended spirosomes for substrate channeling. Commun Biol, 3, 2020
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5D2D
| Crystal structure of human 14-3-3 zeta in complex with CFTR R-domain peptide pS753-pS768 | Descriptor: | 14-3-3 protein zeta/delta, CHLORIDE ION, Cystic fibrosis transmembrane conductance regulator, ... | Authors: | Stevers, L.M, Leysen, S.F.R, Ottmann, C. | Deposit date: | 2015-08-05 | Release date: | 2016-03-16 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR. Proc.Natl.Acad.Sci.USA, 113, 2016
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