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8QGT	5'vRNA-bound Hantaan virus polymerase in monomeric intermediate state Descriptor: RNA (5'-R(P*UP*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L Authors: Durieux Trouilleton, Q, Arragain, B, Malet, H. Deposit date: 2023-09-05 Release date: 2024-03-27 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers. Nat Commun, 15, 2024
8FCS	Structure of pre-miR-31 reveals an active role in Dicer processing Descriptor: microRNA 31 Authors: Kotar, A, Ma, S, Keane, S. Deposit date: 2022-12-01 Release date: 2023-02-22 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structure of pre-miR-31 reveals an active role in Dicer processing. Biorxiv, 2023
4PTF	Ternary crystal structure of yeast DNA polymerase epsilon with template G Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', ... Authors: Jain, R, Rajashankar, K.R, Buku, A, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. Deposit date: 2014-03-10 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.809 Å) Cite: Crystal Structure of Yeast DNA Polymerase epsilon Catalytic Domain. Plos One, 9, 2014
5X70	Crystal structure of Rice Dwarf Virus P5 in complex with a ssRNA oligomer Descriptor: RNA (5'-R(P*GP*GP*CP*AP*AP*A)-3'), mRNA capping enzyme P5 Authors: Nakamichi, Y, Higashiura, A, Nakagawa, A. Deposit date: 2017-02-23 Release date: 2018-02-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystal structure of capping enzyme from Rice dwarf virus To Be Published
5YVH	Crystal structure of Karyopherin beta2 in complex with FUS(371-526) Descriptor: RNA-binding protein FUS, Transportin-1 Authors: Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. Deposit date: 2017-11-25 Release date: 2018-05-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
7EF0	Crystal structure of maize SHH2 SAWADEE domain in complex with an H3K9M peptide Descriptor: HB transcription factor, Histone H3.2, ZINC ION Authors: Wang, Y, Du, J. Deposit date: 2021-03-20 Release date: 2021-06-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Recognition of H3K9me1 by maize RNA-directed DNA methylation factor SHH2. J Integr Plant Biol, 63, 2021
7Q7X	Crystal structure of the methyltransferase-ribozyme 1 (with 1-methyl-adenosine) Descriptor: GUANINE, MAGNESIUM ION, RNA 1, ... Authors: Mieczkowski, M, Hoebartner, C. Deposit date: 2021-11-09 Release date: 2022-03-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure and mechanism of the methyltransferase ribozyme MTR1. Nat.Chem.Biol., 18, 2022
7Q7Y	Crystal structure of the methyltransferase-ribozyme 1 (1-benzyl-adenosine derivative) Descriptor: GUANINE, MAGNESIUM ION, RNA 1, ... Authors: Mieczkowski, M, Hoebartner, C. Deposit date: 2021-11-09 Release date: 2022-03-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure and mechanism of the methyltransferase ribozyme MTR1. Nat.Chem.Biol., 18, 2022
7Q80	Crystal structure of the methyltransferase-ribozyme 1, no Magnesium condition (with 1-methyl-adenosine) Descriptor: GUANINE, RNA 1, RNA 2, ... Authors: Mieczkowski, M, Hoebartner, C. Deposit date: 2021-11-09 Release date: 2022-03-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.14 Å) Cite: Structure and mechanism of the methyltransferase ribozyme MTR1. Nat.Chem.Biol., 18, 2022
7Q82	Crystal structure of the methyltransferase-ribozyme 1, Thallium derivative (with 1-methyl-adenosine) Descriptor: GUANINE, MAGNESIUM ION, RNA 1, ... Authors: Mieczkowski, M, Hoebartner, C. Deposit date: 2021-11-09 Release date: 2022-03-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure and mechanism of the methyltransferase ribozyme MTR1. Nat.Chem.Biol., 18, 2022
7Q7Z	Crystal structure of the methyltransferase-ribozyme 1 (with 1-benzylamine-adenosine) Descriptor: GUANINE, MAGNESIUM ION, RNA 1, ... Authors: Mieczkowski, M, Hoebartner, C. Deposit date: 2021-11-09 Release date: 2022-03-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.26 Å) Cite: Structure and mechanism of the methyltransferase ribozyme MTR1. Nat.Chem.Biol., 18, 2022
5HZI	Crystal structure of photoinhibitable Intersectin1 containing C450M mutant LOV2 domain Descriptor: FLAVIN MONONUCLEOTIDE, Intersectin-1,NPH1-1,Intersectin-1 Authors: Tarnawski, M, Dagliyan, O, Chu, P.H, Shirvanyants, D, Dokholyan, N.V, Hahn, K.M, Schlichting, I. Deposit date: 2016-02-02 Release date: 2016-12-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Engineering extrinsic disorder to control protein activity in living cells. Science, 354, 2016
5HZJ	Crystal structure of photoinhibitable Intersectin1 containing wildtype LOV2 domain Descriptor: FLAVIN MONONUCLEOTIDE, Intersectin-1,NPH1-1,Intersectin-1 Authors: Tarnawski, M, Dagliyan, O, Chu, P.H, Shirvanyants, D, Dokholyan, N.V, Hahn, K.M, Schlichting, I. Deposit date: 2016-02-02 Release date: 2016-12-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Engineering extrinsic disorder to control protein activity in living cells. Science, 354, 2016
5IOS	Flavin-dependent thymidylate synthase R90A variant in complex with FAD and deoxyuridine monophosphate Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase ThyX Authors: Bernard, S.M, Stull, F.W, Smith, J.L. Deposit date: 2016-03-08 Release date: 2016-06-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase. Biochemistry, 55, 2016
5IOT	Flavin-dependent thymidylate synthase R174A variant in complex with FAD and dUMP Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Thymidylate synthase ThyX Authors: Bernard, S.M, Stull, F.W, Smith, J.L. Deposit date: 2016-03-08 Release date: 2016-06-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase. Biochemistry, 55, 2016
1XTJ	structure of human UAP56 in complex with ADP Descriptor: ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Shi, H, Cordin, O, Minder, C.M, Linder, P, Xu, R.-M. Deposit date: 2004-10-22 Release date: 2004-12-14 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of the human ATP-dependent splicing and export factor UAP56 Proc.Natl.Acad.Sci.USA, 101, 2004
8Q70	tRNA pseudouridine synthase A homodimer Descriptor: CHLORIDE ION, MAGNESIUM ION, tRNA pseudouridine synthase A Authors: Pacesa, M, Correia, B.E, Levy, E.D. Deposit date: 2023-08-15 Release date: 2023-11-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.85 Å) Cite: An atlas of protein homo-oligomerization across domains of life. Cell, 187, 2024
8BTX	Structure of human Archease Descriptor: Protein archease Authors: Kopp, J, Gerber, J.L, Peschek, J. Deposit date: 2022-11-30 Release date: 2023-12-13 Last modified: 2024-04-17 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease. Nat Commun, 15, 2024
2LK0	Solution structure and binding studies of the RanBP2-type zinc finger of RBM5 Descriptor: RNA-binding protein 5, ZINC ION Authors: Farina, B, Pellecchia, M. Deposit date: 2011-09-30 Release date: 2011-12-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Targeting Zinc Finger Domains with Small Molecules: Solution Structure and Binding Studies of the RanBP2-Type Zinc Finger of RBM5. Chembiochem, 12, 2011
4HJR	Crystal structure of F2YRS Descriptor: Tyrosine-tRNA ligase Authors: Wang, J, Tian, C, Gong, W, Li, F, Shi, P, Li, J, Ding, W. Deposit date: 2012-10-13 Release date: 2013-03-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A genetically encoded 19F NMR probe for tyrosine phosphorylation. Angew.Chem.Int.Ed.Engl., 52, 2013
7AS4	Recombinant human gTuRC Descriptor: Actin, cytoplasmic 1, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Serna, M, Fernandez-Leiro, R, Llorca, O. Deposit date: 2020-10-26 Release date: 2021-01-20 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (4.13 Å) Cite: Assembly of the asymmetric human gamma-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase. Sci Adv, 6, 2020
7SCI	AM0627 metallopeptidase from Akkermansia muciniphila Descriptor: CHLORIDE ION, FORMIC ACID, Peptidase M60 domain-containing protein, ... Authors: Fernandez, D, Bertozzi, C.R, Shon, D.J. Deposit date: 2021-09-28 Release date: 2022-04-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences. J.Biol.Chem., 298, 2022
8URB	Porcine epidemic diarrhea virus complete core polymerase complex Descriptor: RNA (33-MER), RNA (55-MER), ZINC ION, ... Authors: Anderson, T.K, Kirchdoerfer, R.N. Deposit date: 2023-10-25 Release date: 2023-11-15 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: An alphacoronavirus polymerase structure reveals conserved co-factor functions. Biorxiv, 2023
8DPG	Cryo-EM structure of the 5HT2C receptor (INI isoform) bound to psilocin Descriptor: 3-[2-(dimethylamino)ethyl]-1~{H}-indol-4-ol, 5-hydroxytryptamine receptor 2C, Antibody fragment scFv16, ... Authors: Gumpper, R.H, Fay, J.F, Roth, B.L. Deposit date: 2022-07-15 Release date: 2022-08-24 Last modified: 2022-08-31 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Molecular insights into the regulation of constitutive activity by RNA editing of 5HT 2C serotonin receptors. Cell Rep, 40, 2022
8DPI	Cryo-EM structure of the 5HT2C receptor (VSV isoform) bound to lorcaserin Descriptor: (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, 5-hydroxytryptamine receptor 2C, Antibody fragment scFv16, ... Authors: Gumpper, R.H, Fay, J.F, Roth, B.L. Deposit date: 2022-07-15 Release date: 2022-08-24 Last modified: 2022-08-31 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular insights into the regulation of constitutive activity by RNA editing of 5HT 2C serotonin receptors. Cell Rep, 40, 2022

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