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5IOS

Flavin-dependent thymidylate synthase R90A variant in complex with FAD and deoxyuridine monophosphate

Summary for 5IOS
Entry DOI10.2210/pdb5ios/pdb
Related5ioq 5ior 5iot
DescriptorThymidylate synthase ThyX, FLAVIN-ADENINE DINUCLEOTIDE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordsfad-dependent, nucleotide biosynthesis, reductive methylation, transferase
Biological sourceThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Total number of polymer chains4
Total formula weight114045.18
Authors
Bernard, S.M.,Stull, F.W.,Smith, J.L. (deposition date: 2016-03-08, release date: 2016-06-08, Last modification date: 2023-09-27)
Primary citationStull, F.W.,Bernard, S.M.,Sapra, A.,Smith, J.L.,Zuiderweg, E.R.,Palfey, B.A.
Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase.
Biochemistry, 55:3261-3269, 2016
Cited by
PubMed: 27214228
DOI: 10.1021/acs.biochem.6b00510
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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