3VSS
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![BU of 3vss by Molmil](/molmil-images/mine/3vss) | Microbacterium saccharophilum K-1 beta-fructofuranosidase catalytic domain complexed with fructose | Descriptor: | Beta-fructofuranosidase, beta-D-fructofuranose | Authors: | Tonozuka, T, Tamaki, A, Yokoi, G, Miyazaki, T, Ichikawa, M, Nishikawa, A, Ohta, Y, Hidaka, Y, Katayama, K, Hatada, Y, Ito, T, Fujita, K. | Deposit date: | 2012-05-08 | Release date: | 2012-08-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of a lactosucrose-producing enzyme, Arthrobacter sp. K-1 beta-fructofuranosidase Enzyme.Microb.Technol., 51, 2012
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1EPF
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![BU of 1epf by Molmil](/molmil-images/mine/1epf) | CRYSTAL STRUCTURE OF THE TWO N-TERMINAL IMMUNOGLOBULIN DOMAINS OF THE NEURAL CELL ADHESION MOLECULE (NCAM) | Descriptor: | CALCIUM ION, PROTEIN (NEURAL CELL ADHESION MOLECULE) | Authors: | Kasper, C, Rasmussen, H, Kastrup, J.S, Ikemizu, S, Jones, E.Y, Berezin, V, Bock, E, Larsen, I.K. | Deposit date: | 2000-03-29 | Release date: | 2000-10-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of cell-cell adhesion by NCAM. Nat.Struct.Biol., 7, 2000
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1EQF
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![BU of 1eqf by Molmil](/molmil-images/mine/1eqf) | CRYSTAL STRUCTURE OF THE DOUBLE BROMODOMAIN MODULE FROM HUMAN TAFII250 | Descriptor: | RNA POLYMERASE II TRANSCRIPTION INITIATION FACTOR, SULFATE ION | Authors: | Jacobson, R.H, Ladurner, A.G, King, D.S, Tjian, R. | Deposit date: | 2000-04-04 | Release date: | 2000-06-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and function of a human TAFII250 double bromodomain module. Science, 288, 2000
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6L2D
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![BU of 6l2d by Molmil](/molmil-images/mine/6l2d) | Crystal structure of a cupin protein (tm1459) in copper (Cu) substituted form | Descriptor: | COPPER (II) ION, Cupin_2 domain-containing protein | Authors: | Fujieda, N, Ichihashi, H, Nishikawa, Y, Kurisu, G, Itoh, S. | Deposit date: | 2019-10-03 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.198 Å) | Cite: | Cupin Variants as a Macromolecular Ligand Library for Stereoselective Michael Addition of Nitroalkanes. Angew.Chem.Int.Ed.Engl., 59, 2020
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4UBL
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![BU of 4ubl by Molmil](/molmil-images/mine/4ubl) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 9.26 MGy | Descriptor: | DIETHYL HYDROGEN PHOSPHATE, E3 | Authors: | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | Deposit date: | 2014-08-13 | Release date: | 2015-08-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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3VTA
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![BU of 3vta by Molmil](/molmil-images/mine/3vta) | Crystal Structure of cucumisin, a subtilisin-like endoprotease from Cucumis melo L | Descriptor: | Cucumisin, DIISOPROPYL PHOSPHONATE, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Murayama, K, Kato-Murayama, M, Hosaka, T, Sotokawauchi, A, Shirouzu, M, Arima, K, Yokoyama, S. | Deposit date: | 2012-05-23 | Release date: | 2012-08-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of cucumisin, a subtilisin-like endoprotease from Cucumis melo L J.Mol.Biol., 423, 2012
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6L3X
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![BU of 6l3x by Molmil](/molmil-images/mine/6l3x) | Discovery of novel peptidomimetic boronate ClpP inhibitors with noncanonical enzyme mechanism as potent virulence blockers in vitro and in vivo | Descriptor: | ATP-dependent Clp protease proteolytic subunit, [(1~{R})-1-[[(2~{S})-2-[[2,5-bis(chloranyl)phenyl]carbonylamino]-3-(1~{H}-indol-3-yl)propanoyl]amino]-3-methyl-butyl]boronic acid | Authors: | Luo, Y.F, Bao, R, Ju, Y, He, L.H. | Deposit date: | 2019-10-15 | Release date: | 2020-08-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3054 Å) | Cite: | Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockersin Vitroandin Vivo. J.Med.Chem., 63, 2020
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6LDS
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4UCT
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![BU of 4uct by Molmil](/molmil-images/mine/4uct) | Fragment bound to H.influenza NAD dependent DNA ligase | Descriptor: | 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 2-amino-6-methyl-5-(propan-2-yloxy)-3H-[1,2,4]triazolo[1,5-a]pyrimidin-8-ium, DNA LIGASE | Authors: | Hale, M, Brassington, C, Carcanague, D, Embrey, K, Eyermann, C.J, Giacobbe, R.A, Gingipali, L, Gowravaram, M, Harang, J, Howard, T, Ioannidis, G, Jahic, H, Kutschke, A, Laganas, V.A, Loch, J, Miller, M.D, Murphy-Benenato, K.E, Oguto, H, Otterbein, L, Patel, S.J, Shapiro, A.B, Boriack-Sjodin, P.A. | Deposit date: | 2014-12-04 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | From Fragments to Leads: Novel Bacterial Nad+-Dependent DNA Ligase Inhibitors Tetrahedron Lett., 56, 2015
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1E9Y
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![BU of 1e9y by Molmil](/molmil-images/mine/1e9y) | Crystal structure of Helicobacter pylori urease in complex with acetohydroxamic acid | Descriptor: | ACETOHYDROXAMIC ACID, NICKEL (II) ION, UREASE SUBUNIT ALPHA, ... | Authors: | Ha, N.-C, Oh, S.-T, Oh, B.-H. | Deposit date: | 2000-11-01 | Release date: | 2001-11-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Supramolecular Assembly and Acid Resistance of Helicobacter Pylori Urease Nat.Struct.Biol., 8, 2001
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1E6I
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![BU of 1e6i by Molmil](/molmil-images/mine/1e6i) | |
6LGM
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![BU of 6lgm by Molmil](/molmil-images/mine/6lgm) | |
1E8Q
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![BU of 1e8q by Molmil](/molmil-images/mine/1e8q) | Characterisation of the cellulose docking domain from Piromyces equi | Descriptor: | Endoglucanase 45A | Authors: | Raghothama, S, Eberhardt, R.Y, White, P, Hazlewood, G.P, Gilbert, H.J, Simpson, P.J, Williamson, M.P. | Deposit date: | 2000-09-28 | Release date: | 2001-09-07 | Last modified: | 2018-06-20 | Method: | SOLUTION NMR | Cite: | Characterization of a cellulosome dockerin domain from the anaerobic fungus Piromyces equi. Nat. Struct. Biol., 8, 2001
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1EBL
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![BU of 1ebl by Molmil](/molmil-images/mine/1ebl) | THE 1.8 A CRYSTAL STRUCTURE AND ACTIVE SITE ARCHITECTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE III (FABH) FROM ESCHERICHIA COLI | Descriptor: | BETA-KETOACYL-ACP SYNTHASE III, COENZYME A | Authors: | Davies, C, Heath, R.J, White, S.W, Rock, C.O. | Deposit date: | 2000-01-24 | Release date: | 2000-02-11 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli. Structure Fold.Des., 8, 2000
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6LIG
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6L8J
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![BU of 6l8j by Molmil](/molmil-images/mine/6l8j) | Crystal structure of CYP97A3 mutant S290D/W300L/S304V in complex with retinal | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Protein LUTEIN DEFICIENT 5, chloroplastic, ... | Authors: | Niu, G, Guo, Q, Liu, L. | Deposit date: | 2019-11-06 | Release date: | 2020-06-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Structural basis for plant lutein biosynthesis from alpha-carotene. Proc.Natl.Acad.Sci.USA, 117, 2020
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6LJ5
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![BU of 6lj5 by Molmil](/molmil-images/mine/6lj5) | Crystal structure of NDM-1 in complex with D-captopril derivative wss04145 | Descriptor: | 1,2-ETHANEDIOL, 1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-4-carboxylic acid, Metallo-beta-lactamase type 2, ... | Authors: | Zhang, H, Ma, G. | Deposit date: | 2019-12-13 | Release date: | 2020-12-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors. Bioorg.Med.Chem., 29, 2020
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6LJG
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![BU of 6ljg by Molmil](/molmil-images/mine/6ljg) | Crassostrea gigas ferritin mutant-D119G | Descriptor: | FE (III) ION, Ferritin | Authors: | Li, H, Zang, J, Tan, X, Wang, Z, Du, M. | Deposit date: | 2019-12-15 | Release date: | 2020-12-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Crassostrea gigas ferritin mutant-D119G To Be Published
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6LJP
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![BU of 6ljp by Molmil](/molmil-images/mine/6ljp) | Crystal structure of human galectin-16 | Descriptor: | Galectin-16 | Authors: | Su, J. | Deposit date: | 2019-12-17 | Release date: | 2020-10-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human galectin-16 has a pseudo ligand binding site and plays a role in regulating c-Rel-mediated lymphocyte activity. Biochim Biophys Acta Gen Subj, 1865, 2020
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6LJU
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![BU of 6lju by Molmil](/molmil-images/mine/6lju) | Crystal structure of human FABP4 in complex with a novel inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2-[[3-chloranyl-4-(methylamino)-2-phenyl-phenyl]amino]benzoic acid, Fatty acid-binding protein, ... | Authors: | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | Deposit date: | 2019-12-17 | Release date: | 2020-04-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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4UB9
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![BU of 4ub9 by Molmil](/molmil-images/mine/4ub9) | Structural and catalytic characterization of molinate hydrolase | Descriptor: | Molinate hydrolase, ZINC ION | Authors: | Leite, J.P, Duarte, M, Paiva, A, Ferreira-da-Silva, F, Matias, P.M, Nunes, O, Gales, L. | Deposit date: | 2014-08-12 | Release date: | 2015-06-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structure-guided engineering of molinate hydrolase for the degradation of thiocarbamate pesticides. Plos One, 10, 2015
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6LD9
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4UE0
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![BU of 4ue0 by Molmil](/molmil-images/mine/4ue0) | |
4UFW
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![BU of 4ufw by Molmil](/molmil-images/mine/4ufw) | Plasmodium vivax N-myristoyltransferase in complex with a pyridyl inhibitor (compound 22) | Descriptor: | 2-oxopentadecyl-CoA, 4-chloranyl-N-[2-(3-methoxyphenyl)ethanimidoyl]-2-piperidin-4-yloxy-benzamide, CHLORIDE ION, ... | Authors: | Yu, Z, Brannigan, J.A, Rangachari, K, Heal, W.P, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | Deposit date: | 2015-03-19 | Release date: | 2016-02-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Pyridyl-Based Inhibitors of Plasmodium Falciparum N-Myristoyltransferase Medchemcomm, 6, 2015
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6LF6
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![BU of 6lf6 by Molmil](/molmil-images/mine/6lf6) | Crystal structure of ZmCGTa in complex with UDP | Descriptor: | UDP-glycosyltransferase 708A6, URIDINE-5'-DIPHOSPHATE | Authors: | Gao, H.M, Yun, C.H. | Deposit date: | 2019-11-29 | Release date: | 2020-11-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.044 Å) | Cite: | Dissection of the general two-step di- C -glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants. Proc.Natl.Acad.Sci.USA, 117, 2020
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