7NV0
| Human Pol Kappa holoenzyme with wt PCNA | Descriptor: | DNA Primer, DNA Template, DNA polymerase kappa, ... | Authors: | Lancey, C, De Biasio, A, Hamdan, S.M. | Deposit date: | 2021-03-15 | Release date: | 2021-11-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA. Nat Commun, 12, 2021
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5N61
| RNA polymerase I initially transcribing complex | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | Deposit date: | 2017-02-14 | Release date: | 2017-04-05 | Last modified: | 2019-10-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Basis of RNA Polymerase I Transcription Initiation. Cell, 169, 2017
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5MED
| Cyanothece lipoxygenase 2 (CspLOX2) | Descriptor: | 1,3-PROPANDIOL, 1,4-BUTANEDIOL, 1-BUTANOL, ... | Authors: | Newie, J, Neumann, P, Werner, M, Mata, R.A, Ficner, R, Feussner, I. | Deposit date: | 2016-11-14 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Lipoxygenase 2 from Cyanothece sp. controls dioxygen insertion by steric shielding and substrate fixation. Sci Rep, 7, 2017
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5N7F
| MAGI-1 complexed with a pRSK1 peptide | Descriptor: | CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... | Authors: | Gogl, G, Nyitray, L. | Deposit date: | 2017-02-20 | Release date: | 2017-11-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
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5N5Y
| Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation III) | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | Deposit date: | 2017-02-14 | Release date: | 2017-04-05 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Structural Basis of RNA Polymerase I Transcription Initiation. Cell, 169, 2017
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5N5Z
| Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation II) | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | Deposit date: | 2017-02-14 | Release date: | 2017-04-05 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Structural Basis of RNA Polymerase I Transcription Initiation. Cell, 169, 2017
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5N7G
| MAGI-1 complexed with a synthetic pRSK1 peptide | Descriptor: | CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... | Authors: | Gogl, G, Nyitray, L. | Deposit date: | 2017-02-20 | Release date: | 2017-11-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
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4M82
| The structure of E292S glycosynthase variant of exo-1,3-beta-glucanase from Candida albicans complexed with p-nitrophenyl-gentiobioside (product) at 1.6A resolution | Descriptor: | 1,2-ETHANEDIOL, 4-nitrophenyl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside, EXO-1,3-BETA-GLUCANASE, ... | Authors: | Nakatani, Y, Cutfield, S.M, Larsen, D.S, Cutfield, J.F. | Deposit date: | 2013-08-12 | Release date: | 2014-06-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.592 Å) | Cite: | Major Change in Regiospecificity for the Exo-1,3-beta-glucanase from Candida albicans following Its Conversion to a Glycosynthase. Biochemistry, 53, 2014
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4K6N
| Crystal structure of yeast 4-amino-4-deoxychorismate lyase | Descriptor: | Aminodeoxychorismate lyase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Dai, Y.-N, Chi, C.-B, Zhou, K, Cheng, W, Jiang, Y.-L, Ren, Y.-M, Chen, Y, Zhou, C.-Z. | Deposit date: | 2013-04-16 | Release date: | 2013-07-10 | Last modified: | 2013-10-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase J.Biol.Chem., 288, 2013
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4NX0
| Crystal structure of Abp-WT, a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus | Descriptor: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | Authors: | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | Deposit date: | 2013-12-08 | Release date: | 2014-12-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6 Acta Crystallogr.,Sect.D, 70, 2014
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4NKK
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4NZF
| Crystal structure of Abp-D197A (a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus), in complex with arabinose | Descriptor: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | Authors: | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | Deposit date: | 2013-12-12 | Release date: | 2014-12-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6 Acta Crystallogr.,Sect.D, 70, 2014
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4BU1
| Crystal structure of Rad4 BRCT1,2 in complex with a Crb2 phosphopeptide | Descriptor: | 1,2-ETHANEDIOL, DNA REPAIR PROTEIN RHP9, GLYCEROL, ... | Authors: | Qu, M, Rappas, M, Wardlaw, C.P, Garcia, V, Carr, A.M, Oliver, A.W, Du, L.L, Pearl, L.H. | Deposit date: | 2013-06-19 | Release date: | 2013-10-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(Topbp1.). Mol.Cell, 51, 2013
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4BMC
| Crystal structure of s.pombe Rad4 BRCT1,2 | Descriptor: | CHLORIDE ION, S-M CHECKPOINT CONTROL PROTEIN RAD4 | Authors: | Meng, Q, Rappas, M, Wardlaw, C.P, Garcia, V, Carr, A.M, Oliver, A.W, Du, L.L, Pearl, L.H. | Deposit date: | 2013-05-07 | Release date: | 2013-10-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.982 Å) | Cite: | Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(Topbp1.). Mol.Cell, 51, 2013
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7AI7
| MutS in Intermediate state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*CP*TP*TP*AP*GP*CP*TP*TP*AP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*TP*AP*AP*CP*TP*AP*AP*G)-3'), ... | Authors: | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | Deposit date: | 2020-09-26 | Release date: | 2021-03-31 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
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7AI5
| MutS in Scanning state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*AP*AP*TP*TP*CP*GP*CP*CP*CP*TP*AP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*TP*AP*GP*GP*GP*CP*GP*AP*AP*TP*TP*GP*GP*GP*TP*AP*CP*CP*G)-3'), ... | Authors: | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | Deposit date: | 2020-09-26 | Release date: | 2021-03-31 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
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7AI6
| MutS in mismatch bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein MutS | Authors: | Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H. | Deposit date: | 2020-09-26 | Release date: | 2021-03-31 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | The selection process of licensing a DNA mismatch for repair. Nat.Struct.Mol.Biol., 28, 2021
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4BSS
| Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ... | Authors: | Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P. | Deposit date: | 2013-06-11 | Release date: | 2013-06-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Cell Rep., 3, 2013
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4BSU
| Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ... | Authors: | Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P. | Deposit date: | 2013-06-11 | Release date: | 2013-06-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Cell Rep., 3, 2013
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7AE1
| Cryo-EM structure of human RNA Polymerase III elongation complex 1 | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | Deposit date: | 2020-09-17 | Release date: | 2021-02-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
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7AOV
| Crystal Structure of a TRPM2 Domain | Descriptor: | Transient receptor potential cation channel subfamily M member 2, ZINC ION | Authors: | Sander, S, Tidow, H. | Deposit date: | 2020-10-15 | Release date: | 2022-03-02 | Last modified: | 2022-08-17 | Method: | X-RAY DIFFRACTION (2.00001621 Å) | Cite: | The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn 2+ -binding domain essential for structural integrity and channel activity. Protein Sci., 31, 2022
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7ADD
| Transcription termination intermediate complex IIIa | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Said, N, Hilal, T, Loll, B, Wahl, C.M. | Deposit date: | 2020-09-14 | Release date: | 2020-11-25 | Last modified: | 2021-02-03 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho. Science, 371, 2021
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7AE3
| Cryo-EM structure of human RNA Polymerase III elongation complex 3 | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | Deposit date: | 2020-09-17 | Release date: | 2021-02-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
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7ADE
| Transcription termination complex IVa | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Said, N, Hilal, T, Loll, B, Wahl, C.M. | Deposit date: | 2020-09-14 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho. Science, 371, 2021
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7AEA
| Cryo-EM structure of human RNA Polymerase III elongation complex 2 | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | Deposit date: | 2020-09-17 | Release date: | 2021-02-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
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