6R4J
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![BU of 6r4j by Molmil](/molmil-images/mine/6r4j) | Crystal structure of human GFAT-1 G451E in complex with UDP-GlcNAc | Descriptor: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, ... | Authors: | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | Deposit date: | 2019-03-22 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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8JDL
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![BU of 8jdl by Molmil](/molmil-images/mine/8jdl) | Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2023-05-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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6V82
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![BU of 6v82 by Molmil](/molmil-images/mine/6v82) | Crystal structure of tryptophan synthase from Chlamydia trachomatis D/UW-3/CX | Descriptor: | SULFATE ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain, ... | Authors: | Michalska, K, Maltseva, N, Jedrzejczak, R, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-12-10 | Release date: | 2020-12-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.424 Å) | Cite: | Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB. Protein Sci., 30, 2021
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6WVE
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![BU of 6wve by Molmil](/molmil-images/mine/6wve) | Chicken SPCS1 | Descriptor: | Green fluorescent protein,Chicken Signal Peptidase Complex Subunit 1,Green fluorescent protein | Authors: | Liu, S, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2021-01-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.429 Å) | Cite: | Termini restraining of small membrane proteins enables structure determination at near-atomic resolution. Sci Adv, 6, 2020
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6L2C
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![BU of 6l2c by Molmil](/molmil-images/mine/6l2c) | Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA | Descriptor: | Acetyl-CoA-acetyltransferase, putative, COENZYME A | Authors: | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | Deposit date: | 2019-10-03 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
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6QQB
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![BU of 6qqb by Molmil](/molmil-images/mine/6qqb) | |
4W6L
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![BU of 4w6l by Molmil](/molmil-images/mine/4w6l) | |
8SMU
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![BU of 8smu by Molmil](/molmil-images/mine/8smu) | Integral fusion of the HtaA CR2 domain from Corynebacterium diphtheriae within EGFP | Descriptor: | CHLORIDE ION, GLYCEROL, HtaACR2 integral fusion within enhanced green fluorescent protein, ... | Authors: | Mahoney, B.J, Cascio, D, Clubb, R.T. | Deposit date: | 2023-04-26 | Release date: | 2023-09-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Development and atomic structure of a new fluorescence-based sensor to probe heme transfer in bacterial pathogens. J.Inorg.Biochem., 249, 2023
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8W2L
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![BU of 8w2l by Molmil](/molmil-images/mine/8w2l) | TRPM7 structure in complex with anticancer agent CCT128930 in closed state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium, ... | Authors: | Nadezhdin, K.D, Sobolevsky, A.I. | Deposit date: | 2024-02-20 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930. Cell Rep, 43, 2024
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8Q5I
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![BU of 8q5i by Molmil](/molmil-images/mine/8q5i) | Structure of Candida albicans 80S ribosome in complex with cephaeline | Descriptor: | 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ... | Authors: | Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M. | Deposit date: | 2023-08-09 | Release date: | 2023-09-13 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy Biopolym Cell, 2023
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1NJJ
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![BU of 1njj by Molmil](/molmil-images/mine/1njj) | |
5J3N
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![BU of 5j3n by Molmil](/molmil-images/mine/5j3n) | C-terminal domain of EcoR124I HsdR subunit fused with the pH-sensitive GFP variant ratiometric pHluorin | Descriptor: | Green fluorescent protein,HsdR | Authors: | Grinkevich, P, Iermak, I, Luedtke, N, Mesters, J.R, Ettrich, R, Ludwig, J. | Deposit date: | 2016-03-31 | Release date: | 2017-04-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of a novel domain of the motor subunit of the Type I restriction enzyme EcoR124 involved in complex assembly and DNA binding. J. Biol. Chem., 293, 2018
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8EWC
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![BU of 8ewc by Molmil](/molmil-images/mine/8ewc) | Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure II | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-22 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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4Q9Q
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![BU of 4q9q by Molmil](/molmil-images/mine/4q9q) | Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | Descriptor: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | Authors: | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2014-05-01 | Release date: | 2014-06-18 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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5XV6
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![BU of 5xv6 by Molmil](/molmil-images/mine/5xv6) | Crystal structure of ATG101-ATG13HORMA | Descriptor: | Autophagy-related protein 101, Autophagy-related protein 13 | Authors: | Kim, B.-W, Song, H.K. | Deposit date: | 2017-06-26 | Release date: | 2018-07-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.455 Å) | Cite: | The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation. Autophagy, 14, 2018
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4KW8
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![BU of 4kw8 by Molmil](/molmil-images/mine/4kw8) | |
8A98
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![BU of 8a98 by Molmil](/molmil-images/mine/8a98) | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT | Descriptor: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | Authors: | Rajan, K.S, Yonath, A, Bashan, A. | Deposit date: | 2022-06-28 | Release date: | 2023-10-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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8CIV
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![BU of 8civ by Molmil](/molmil-images/mine/8civ) | Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | Deposit date: | 2023-02-10 | Release date: | 2023-09-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.47 Å) | Cite: | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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6S67
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![BU of 6s67 by Molmil](/molmil-images/mine/6s67) | Structure of the Fluorescent Protein AausFP1 from Aequorea cf. australis at pH 7.0 | Descriptor: | Aequorea cf. australis fluorescent protein 1 (AausFP1), GLYCEROL | Authors: | Depernet, H, Gotthard, G, Lambert, G.G, Shaner, N.C, Royant, A. | Deposit date: | 2019-07-02 | Release date: | 2020-07-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Aequorea's secrets revealed: New fluorescent proteins with unique properties for bioimaging and biosensing. Plos Biol., 18, 2020
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8OVA
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6GEZ
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![BU of 6gez by Molmil](/molmil-images/mine/6gez) | THE STRUCTURE OF TWITCH-2B N532F | Descriptor: | CALCIUM ION, FORMIC ACID, Green fluorescent protein,Optimized Ratiometric Calcium Sensor,Green fluorescent protein,Green fluorescent protein | Authors: | Trigo Mourino, P, Paulat, M, Thestrup, T, Griesbeck, O, Griesinger, C, Becker, S. | Deposit date: | 2018-04-27 | Release date: | 2019-08-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Dynamic tuning of FRET in a green fluorescent protein biosensor. Sci Adv, 5, 2019
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4D2C
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![BU of 4d2c by Molmil](/molmil-images/mine/4d2c) | Structure of a di peptide bound POT family peptide transporter | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... | Authors: | Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S. | Deposit date: | 2014-05-09 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters. Embo Rep., 15, 2014
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7WVI
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![BU of 7wvi by Molmil](/molmil-images/mine/7wvi) | Crystal structure of SIA28 | Descriptor: | Heavy chain of SIA28, Light chain of SIA28 | Authors: | Chen, Y, Qi, J, Gao, G.F. | Deposit date: | 2022-02-10 | Release date: | 2023-01-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7JRN
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![BU of 7jrn by Molmil](/molmil-images/mine/7jrn) | Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617 | Descriptor: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, SULFATE ION, ... | Authors: | Sacco, M, Ma, C, Wang, J, Chen, Y. | Deposit date: | 2020-08-12 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay. Acs Cent.Sci., 7, 2021
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2RH5
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![BU of 2rh5 by Molmil](/molmil-images/mine/2rh5) | Structure of Apo Adenylate Kinase from Aquifex Aeolicus | Descriptor: | Adenylate kinase | Authors: | Thai, V, Wolf-Watz, M, Fenn, T, Pozharski, E, Wilson, M.A, Petsko, G.A, Kern, D. | Deposit date: | 2007-10-05 | Release date: | 2007-12-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Intrinsic motions along an enzymatic reaction trajectory. Nature, 450, 2007
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