5K77
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![BU of 5k77 by Molmil](/molmil-images/mine/5k77) | Dbr1 in complex with 7-mer branched RNA | Descriptor: | FE (II) ION, HYDROXIDE ION, RNA lariat debranching enzyme, ... | Authors: | Clark, N.E, Taylor, A.B, Hart, P.J. | Deposit date: | 2016-05-25 | Release date: | 2016-12-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5JZO
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8H9H
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![BU of 8h9h by Molmil](/molmil-images/mine/8h9h) | Crystal structure of ZBTB7A in complex with GACCC-containing sequence | Descriptor: | DNA (5'-D(*TP*AP*AP*GP*GP*AP*CP*CP*CP*AP*GP*AP*T)-3'), DNA (5'-D(P*AP*AP*TP*CP*TP*GP*GP*GP*TP*CP*CP*TP*T)-3'), ZINC ION, ... | Authors: | Yang, Y. | Deposit date: | 2022-10-25 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | ZBTB7A regulates primed-to-naive transition of pluripotent stem cells via recognition of the PNT-associated sequence by zinc fingers 1-2 and recognition of gamma-globin -200 gene element by zinc fingers 1-4. Febs J., 290, 2023
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8HKJ
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![BU of 8hkj by Molmil](/molmil-images/mine/8hkj) | Crystal structure of the CYP102A5 haem Domain isolated from Bacillus cereus | Descriptor: | Bifunctional cytochrome P450/NADPH--P450 reductase, PALMITIC ACID, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Stanfield, J.K, Onoda, H, Sugimoto, H, Shoji, O. | Deposit date: | 2022-11-27 | Release date: | 2023-04-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily. J.Inorg.Biochem., 245, 2023
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5KAT
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![BU of 5kat by Molmil](/molmil-images/mine/5kat) | The structure of SAV2435 bound to TETRAPHENYLPHOSPHONIUM | Descriptor: | GLYCEROL, SA2223 protein, TETRAPHENYLPHOSPHONIUM | Authors: | Moreno, A, Wade, H. | Deposit date: | 2016-06-02 | Release date: | 2016-08-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins. Biochemistry, 55, 2016
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7Y8L
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![BU of 7y8l by Molmil](/molmil-images/mine/7y8l) | Structure of ScIRED-R2-V3 from Streptomyces clavuligerus in complex with 5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole | Descriptor: | 5-[2,5-bis(fluoranyl)phenyl]-3,4-dihydro-2~{H}-pyrrole, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Zhang, L.L, Liu, W.D, Shi, M, Huang, J.W, Yang, Y, Chen, C.C, Guo, R.T. | Deposit date: | 2022-06-24 | Release date: | 2023-06-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Engineered Imine Reductase for Larotrectinib Intermediate Manufacture Acs Catalysis, 12, 2022
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5KCA
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![BU of 5kca by Molmil](/molmil-images/mine/5kca) | Crystal structure of the Cbln1 C1q domain trimer in complex with the amino-terminal domain (ATD) of iGluR Delta-2 (GluD2) | Descriptor: | CALCIUM ION, Cerebellin-1,Cerebellin-1,Cerebellin-1,Glutamate receptor ionotropic, delta-2 | Authors: | Elegheert, J, Aricescu, A.R. | Deposit date: | 2016-06-05 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for integration of GluD receptors within synaptic organizer complexes. Science, 353, 2016
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8HHF
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![BU of 8hhf by Molmil](/molmil-images/mine/8hhf) | The bacterial divisome protein complex FtsB-FtsL-FtsQ | Descriptor: | Cell division protein FtsB, Cell division protein FtsL, Cell division protein FtsQ | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-11-16 | Release date: | 2023-04-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome. Nat Commun, 14, 2023
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7X8L
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5KF6
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5K7H
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![BU of 5k7h by Molmil](/molmil-images/mine/5k7h) | Crystal structure of AibR in complex with the effector molecule isovaleryl coenzyme A | Descriptor: | CHLORIDE ION, Isovaleryl-coenzyme A, NICKEL (II) ION, ... | Authors: | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | Deposit date: | 2016-05-26 | Release date: | 2016-12-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res., 45, 2017
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8HDJ
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5K7Q
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![BU of 5k7q by Molmil](/molmil-images/mine/5k7q) | MicroED structure of thaumatin at 2.5 A resolution | Descriptor: | Thaumatin-1 | Authors: | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | Deposit date: | 2016-05-26 | Release date: | 2017-04-05 | Last modified: | 2018-08-22 | Method: | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | Cite: | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5JO7
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![BU of 5jo7 by Molmil](/molmil-images/mine/5jo7) | Henbane premnaspirodiene synthase (HPS), also known as Henbane vetispiradiene synthase (HVS) from Hyoscyamus muticus | Descriptor: | Vetispiradiene synthase 1 | Authors: | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | Deposit date: | 2016-05-02 | Release date: | 2017-05-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Functional study of terpene synthase from 512 mutant library of henbane premnaspirodiene synthase reveals protein residue interactions To Be Published
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7X9P
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![BU of 7x9p by Molmil](/molmil-images/mine/7x9p) | Crystal structure of human STING complexed with compound BSP17 | Descriptor: | 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein | Authors: | Pan, L, Guan, X, Feng, X, Li, Z, Bian, J. | Deposit date: | 2022-03-15 | Release date: | 2023-03-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery of Selenium-containing STING agonists as orally available anti tumor agents To be published
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5JPA
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![BU of 5jpa by Molmil](/molmil-images/mine/5jpa) | Hexameric HIV-1 CA H12Y mutant | Descriptor: | Capsid Protein P24 | Authors: | Jacques, D.A, James, L.C. | Deposit date: | 2016-05-03 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536, 2016
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5K9S
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![BU of 5k9s by Molmil](/molmil-images/mine/5k9s) | Importin-alpha in complex with HNF1-beta peptide | Descriptor: | HNF1 beta A splice variant 2, Importin subunit alpha-1 | Authors: | Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J. | Deposit date: | 2016-06-01 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Importin-alpha in complex with HNF1-beta peptide To Be Published
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7XBJ
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![BU of 7xbj by Molmil](/molmil-images/mine/7xbj) | Txp40, an insecticidal toxin protein from Xenorhabdus nematophila | Descriptor: | 40kDa insecticidal toxin | Authors: | Kinkar, O, Kumar, A, Prashar, A, Hire, R.S, Makde, R.D. | Deposit date: | 2022-03-21 | Release date: | 2023-03-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The crystal structure of insecticidal protein Txp40 from Xenorhabdus nematophila reveals a two-domain unique binary toxin with homology to the toxin-antitoxin (TA) system. Insect Biochem.Mol.Biol., 164, 2023
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5K1R
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5KC8
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![BU of 5kc8 by Molmil](/molmil-images/mine/5kc8) | Crystal structure of the amino-terminal domain (ATD) of iGluR Delta-2 (GluD2) | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Glutamate receptor ionotropic, ... | Authors: | Elegheert, J, Clay, J.E, Siebold, C, Aricescu, A.R. | Deposit date: | 2016-06-05 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Structural basis for integration of GluD receptors within synaptic organizer complexes. Science, 353, 2016
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7XPV
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![BU of 7xpv by Molmil](/molmil-images/mine/7xpv) | crysteal structure of MtdL-S228A-His soaked with GDP-Fucf and Mn | Descriptor: | MANGANESE (II) ION, Transglycosylse, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{S},3~{S},4~{S},5~{R})-3,4-bis(oxidanyl)-5-[(1~{S})-1-oxidanylethyl]oxolan-2-yl] hydrogen phosphate | Authors: | Li, F.D, He, C. | Deposit date: | 2022-05-05 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding. J.Biol.Chem., 299, 2023
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8HB9
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![BU of 8hb9 by Molmil](/molmil-images/mine/8hb9) | Crystal Structure of Human IDH1 R132H Mutant in Complex with NADPH and Compound IHMT-IDH1-053 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | Authors: | Guo, G, Wang, B, Liu, J, Liu, Q. | Deposit date: | 2022-10-27 | Release date: | 2023-05-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based discovery of IHMT-IDH1-053 as a potent irreversible IDH1 mutant selective inhibitor. Eur.J.Med.Chem., 256, 2023
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5K4A
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7XCA
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![BU of 7xca by Molmil](/molmil-images/mine/7xca) | Crystal structure of the porcine astrovirus capsid spike domain | Descriptor: | CHLORIDE ION, Capsid protein spike domain, MAGNESIUM ION | Authors: | Pan, L.X, Zhang, W.C, Yang, D.F, Yang, L.Y, Liu, H. | Deposit date: | 2022-03-23 | Release date: | 2023-03-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure analysis of porcine astrovirus capsid spike and spike/neutralizing antibody complexes. To Be Published
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5K6O
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