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1IJL
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BU of 1ijl by Molmil
Crystal structure of acidic phospholipase A2 from deinagkistrodon acutus
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2, ZINC ION
Authors:Gu, L, Zhang, H, Song, S, Zhou, Y, Lin, Z.
Deposit date:2001-04-27
Release date:2001-12-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of an acidic phospholipase A2 from the venom of Deinagkistrodon acutus.
Acta Crystallogr.,Sect.D, 58, 2002
2Z7Q
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BU of 2z7q by Molmil
Crystal structure of the N-terminal kinase domain of human RSK-1 bound to AMP-PCP
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-1
Authors:Ikuta, M, Munshi, S.K.
Deposit date:2007-08-28
Release date:2008-05-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors.
Protein Sci., 16, 2007
2BHH
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BU of 2bhh by Molmil
HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 4-HYDROXYPIPERINDINESULFONYL-INDIRUBINE
Descriptor: (2E,3S)-3-HYDROXY-5'-[(4-HYDROXYPIPERIDIN-1-YL)SULFONYL]-3-METHYL-1,3-DIHYDRO-2,3'-BIINDOL-2'(1'H)-ONE, CELL DIVISION PROTEIN KINASE 2
Authors:Schaefer, M, Jautelat, R, Brumby, T, Briem, H, Eisenbrand, G, Schwahn, S, Krueger, M, Luecking, U, Prien, O, Siemeister, G.
Deposit date:2005-01-11
Release date:2005-03-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:From the Insoluble Dye Indirubin Towards Highly Active, Soluble Cdk2-Inhibitors
Chembiochem, 6, 2005
2BJU
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BU of 2bju by Molmil
Plasmepsin II complexed with a highly active achiral inhibitor
Descriptor: N-(R-CARBOXY-ETHYL)-ALPHA-(S)-(2-PHENYLETHYL), PLASMEPSIN II
Authors:Prade, L, Jones, A.F, Boss, C, Richards-Bildstein, S, Meyer, S, Binkert, C, Bur, D.
Deposit date:2005-02-08
Release date:2005-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:X-Ray Structure of Plasmepsin II Complexed with a Potent Achiral Inhibitor.
J.Biol.Chem., 280, 2005
2BMC
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BU of 2bmc by Molmil
Aurora-2 T287D T288D complexed with PHA-680632
Descriptor: (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE, SERINE THREONINE-PROTEIN KINASE 6
Authors:Cameron, A.D, Izzo, G, Sagliano, A, Rusconi, L, Storici, P, Fancelli, D, Berta, D, Bindi, S, Catana, C, Forte, B, Giordano, P, Mantegani, S, Meroni, M, Moll, J, Pittala, V, Severino, D, Tonani, R, Varasi, M, Vulpetti, A, Vianello, P.
Deposit date:2005-03-11
Release date:2005-03-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition.
J.Med.Chem., 48, 2005
1WQU
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BU of 1wqu by Molmil
Solution structure of the human FES SH2 domain
Descriptor: Proto-oncogene tyrosine-protein kinase FES/FPS
Authors:Scott, A, Pantoja-Uceda, D, Koshiba, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Tanaka, A, Sugano, S, Yokoyama, S, Guntert, P, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-10-02
Release date:2005-06-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Src homology 2 domain from the human feline sarcoma oncogene Fes
J.Biomol.NMR, 31, 2005
1WI6
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BU of 1wi6 by Molmil
Solution structure of the RNA binding domain from mouse hypothetical protein BAB23670
Descriptor: Hypothetical protein (RIKEN cDNA 1300006N24)
Authors:Suzuki, S, Muto, Y, Nagata, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-28
Release date:2005-06-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the RNA binding domain from mouse hypothetical protein BAB23670
To be Published
1IO6
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BU of 1io6 by Molmil
GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) C-TERMINAL SH3 DOMAIN COMPLEXED WITH A LIGAND PEPTIDE (NMR, MINIMIZED MEAN STRUCTURE)
Descriptor: A LIGAND PEPTIDE, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Kawasaki, M, Ogura, K, Hatanaka, H, Inagaki, F.
Deposit date:2001-01-25
Release date:2001-02-14
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the C-Terminal SH3 Domain of Grb2 Complexed with a Ligand Peptide: A Ligand Exchange Model of the SH3 Domain
To be Published
1IOG
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BU of 1iog by Molmil
INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES
Descriptor: PROTEIN (INSULIN PRECURSOR)
Authors:Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C.
Deposit date:1998-08-13
Release date:1999-01-13
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
J.Mol.Biol., 284, 1998
2R3O
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BU of 2r3o by Molmil
Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
Descriptor: (5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanol, Cell division protein kinase 2
Authors:Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S.
Deposit date:2007-08-29
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-guided discovery of cyclin-dependent kinase inhibitors.
Biopolymers, 89, 2008
1IMV
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BU of 1imv by Molmil
2.85 A crystal structure of PEDF
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PIGMENT EPITHELIUM-DERIVED FACTOR
Authors:Simonovic, M, Gettins, P.G.W, Volz, K.
Deposit date:2001-05-11
Release date:2001-09-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.
Proc.Natl.Acad.Sci.USA, 98, 2001
1WK1
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BU of 1wk1 by Molmil
Solution structure of Lectin C-type domain derived from a hypothetical protein from C. elegans
Descriptor: Hypothetical protein yk1067a12
Authors:Kobayashi, N, Koshiba, S, Inoue, M, Tochio, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-29
Release date:2004-11-29
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of Lectin C-type domain derived from a hypothetical protein from C. elegans
To be Published
1IP1
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BU of 1ip1 by Molmil
G37A HUMAN LYSOZYME
Descriptor: LYSOZYME C, SODIUM ION
Authors:Takano, K, Yamagata, Y, Yutani, K.
Deposit date:2001-04-20
Release date:2001-11-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein.
Proteins, 45, 2001
1INX
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BU of 1inx by Molmil
A SIALIC ACID DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES
Descriptor: (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:White, C.L, Janakiraman, M.N, Laver, W.G, Philippon, C, Vasella, A, Air, G.M, Luo, M.
Deposit date:1994-09-26
Release date:1995-02-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies.
J.Mol.Biol., 245, 1995
1IZB
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BU of 1izb by Molmil
ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN
Descriptor: INSULIN, ZINC ION
Authors:Xiao, B, Dodson, G.G.
Deposit date:1992-10-16
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
J.Mol.Biol., 228, 1992
1IOH
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BU of 1ioh by Molmil
INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES
Descriptor: PROTEIN (INSULIN PRECURSOR)
Authors:Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C.
Deposit date:1998-08-13
Release date:1999-01-13
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
J.Mol.Biol., 284, 1998
2QG5
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BU of 2qg5 by Molmil
Cryptosporidium parvum calcium dependent protein kinase cgd7_1840
Descriptor: Calcium/calmodulin-dependent protein kinase
Authors:Lunin, V.V, Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Artz, J, Amani, M, Structural Genomics Consortium (SGC)
Deposit date:2007-06-28
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cryptosporidium parvum calcium dependent protein kinase cgd7_1840
To be Published
1WSI
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BU of 1wsi by Molmil
Crystal structure of E.coli RNase HI active site mutant (E48A/K87A/D134N)
Descriptor: Ribonuclease HI
Authors:Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S.
Deposit date:2004-11-07
Release date:2004-11-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:

2BQA
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BU of 2bqa by Molmil
CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Yutani, K.
Deposit date:1998-05-21
Release date:1998-08-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A general rule for the relationship between hydrophobic effect and conformational stability of a protein: stability and structure of a series of hydrophobic mutants of human lysozyme.
J.Mol.Biol., 280, 1998
2BQJ
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BU of 2bqj by Molmil
CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Yutani, K.
Deposit date:1998-05-21
Release date:1998-08-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A general rule for the relationship between hydrophobic effect and conformational stability of a protein: stability and structure of a series of hydrophobic mutants of human lysozyme.
J.Mol.Biol., 280, 1998
2BQC
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BU of 2bqc by Molmil
CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Yutani, K.
Deposit date:1998-05-21
Release date:1998-08-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A general rule for the relationship between hydrophobic effect and conformational stability of a protein: stability and structure of a series of hydrophobic mutants of human lysozyme.
J.Mol.Biol., 280, 1998
2BQB
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BU of 2bqb by Molmil
CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME
Descriptor: LYSOZYME, SODIUM ION
Authors:Takano, K, Yamagata, Y, Yutani, K.
Deposit date:1998-05-21
Release date:1998-08-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A general rule for the relationship between hydrophobic effect and conformational stability of a protein: stability and structure of a series of hydrophobic mutants of human lysozyme.
J.Mol.Biol., 280, 1998
2BY7
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BU of 2by7 by Molmil
Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection
Descriptor: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ...
Authors:Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M.
Deposit date:2005-07-29
Release date:2006-02-06
Last modified:2021-08-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection?
Acta Crystallogr.,Sect.D, 62, 2006
1WTM
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BU of 1wtm by Molmil
X-ray structure of HEW Lysozyme Orthorhombic Crystal formed in the Earth's magnetic field
Descriptor: CHLORIDE ION, Lysozyme C
Authors:Saijo, S, Yamada, Y, Sato, T, Tanaka, N, Matsui, T, Sazaki, G, Nakajima, K, Matsuura, Y.
Deposit date:2004-11-25
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Structural consequences of hen egg-white lysozyme orthorhombic crystal growth in a high magnetic field: validation of X-ray diffraction intensity, conformational energy searching and quantitative analysis of B factors and mosaicity.
Acta Crystallogr.,Sect.D, 61, 2005
2BY6
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BU of 2by6 by Molmil
Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection
Descriptor: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ...
Authors:Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M.
Deposit date:2005-07-29
Release date:2006-02-06
Last modified:2021-08-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection?
Acta Crystallogr.,Sect.D, 62, 2006

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