2BJU
Plasmepsin II complexed with a highly active achiral inhibitor
Summary for 2BJU
| Entry DOI | 10.2210/pdb2bju/pdb |
| Related | 1J8J 1LEE 1LF2 1LF3 1LF4 1M43 1ME6 1PFZ 1SME 1W6H 1W6I |
| Descriptor | PLASMEPSIN II, N-(R-CARBOXY-ETHYL)-ALPHA-(S)-(2-PHENYLETHYL) (3 entities in total) |
| Functional Keywords | plasmepsin, aspartic proteinase, drug design, malaria, aspartyl protease, glycoprotein, hydrolase, zymogen |
| Biological source | PLASMODIUM FALCIPARUM |
| Cellular location | Vacuole: P46925 |
| Total number of polymer chains | 1 |
| Total formula weight | 52727.99 |
| Authors | Prade, L.,Jones, A.F.,Boss, C.,Richards-Bildstein, S.,Meyer, S.,Binkert, C.,Bur, D. (deposition date: 2005-02-08, release date: 2005-04-18, Last modification date: 2011-07-13) |
| Primary citation | Prade, L.,Jones, A.F.,Boss, C.,Richard-Bildstein, S.,Meyer, S.,Binkert, C.,Bur, D. X-Ray Structure of Plasmepsin II Complexed with a Potent Achiral Inhibitor. J.Biol.Chem., 280:23837-, 2005 Cited by PubMed: 15840589DOI: 10.1074/JBC.M501519200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
Download full validation report
