Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005774 | cellular_component | vacuolar membrane |
| A | 0005775 | cellular_component | vacuolar lumen |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0020020 | cellular_component | food vacuole |
| A | 0031910 | cellular_component | cytostome |
| A | 0044002 | biological_process | acquisition of nutrients from host |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE IH4 A1330 |
| Chain | Residue |
| A | ILE14 |
| A | ASP121 |
| A | TYR192 |
| A | ASP214 |
| A | GLY216 |
| A | THR217 |
| A | ILE300 |
| A | IH41331 |
| A | HOH2284 |
| A | HOH2377 |
| A | HOH2378 |
| A | MET15 |
| A | HOH2379 |
| A | ILE32 |
| A | ASP34 |
| A | MET75 |
| A | TYR77 |
| A | PHE111 |
| A | TYR115 |
| A | SER118 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE IH4 A1331 |
| Chain | Residue |
| A | ILE14 |
| A | TYR77 |
| A | THR114 |
| A | GLY216 |
| A | THR217 |
| A | SER218 |
| A | PHE241 |
| A | PHE244 |
| A | LEU287 |
| A | ASN288 |
| A | ILE289 |
| A | LEU292 |
| A | IH41330 |
| A | HOH2186 |
| A | HOH2284 |
| A | HOH2379 |
| A | HOH2381 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE31-VAL42 | |
| A | CYS211-VAL222 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 307 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP214 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| A | THR217 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER215 | |
| A | ASP34 | |
| A | THR35 | |
| A | ASP214 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| A | TYR77 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | THR35 | |
| A | ASP214 | |
| A | THR217 | |
