1I2M
| RAN-RCC1-SO4 COMPLEX | Descriptor: | GTP-BINDING NUCLEAR PROTEIN RAN, REGULATOR OF CHROMOSOME CONDENSATION 1, SULFATE ION | Authors: | Renault, L, Kuhlmann, J, Henkel, A, Wittinghofer, A. | Deposit date: | 2001-02-11 | Release date: | 2001-05-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1). Cell(Cambridge,Mass.), 105, 2001
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1I4T
| CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN | Descriptor: | ARFAPTIN 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 2001-02-23 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
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1I4L
| CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41) | Descriptor: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 2001-02-22 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
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1I4D
| CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITH ARFAPTIN (P21) | Descriptor: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 2001-02-20 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
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1IAQ
| C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, TRANSFORMING PROTEIN P21/H-RAS-1 | Authors: | Spoerner, M, Herrmann, C, Vetter, I.R, Kalbitzer, H.R, Wittinghofer, A. | Deposit date: | 2001-03-23 | Release date: | 2001-06-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Dynamic properties of the Ras switch I region and its importance for binding to effectors. Proc.Natl.Acad.Sci.USA, 98, 2001
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1HH4
| Rac1-RhoGDI complex involved in NADPH oxidase activation | Descriptor: | GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Grizot, S, Faure, J, Fieschi, F, Vignais, P.V, Dagher, M.-C, Pebay-Peyroula, E. | Deposit date: | 2000-12-20 | Release date: | 2001-08-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of the Rac1-Rhogdi Complex Involved in Nadph Oxidase Activation Biochemistry, 40, 2001
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1IOZ
| Crystal Structure of the C-HA-RAS Protein Prepared by the Cell-Free Synthesis | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, TRANSFORMING PROTEIN P21/H-RAS-1 | Authors: | Kigawa, T, Yamaguchi-Nunokawa, E, Kodama, K, Matsuda, T, Yabuki, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-04-18 | Release date: | 2001-10-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selenomethionine incorporation into a protein by cell-free synthesis J.STRUCT.FUNCT.GENOM., 2, 2001
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1K5D
| Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex | Descriptor: | GTP-binding nuclear protein RAN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Seewald, M.J, Koerner, C, Wittinghofer, A, Vetter, I.R. | Deposit date: | 2001-10-10 | Release date: | 2002-02-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | RanGAP mediates GTP hydrolysis without an arginine finger. Nature, 415, 2002
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1K5G
| Crystal structure of Ran-GDP-AlFx-RanBP1-RanGAP complex | Descriptor: | ALUMINUM FLUORIDE, GTP-binding nuclear protein RAN, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Seewald, M.J, Koerner, C, Wittinghofer, A, Vetter, I.R. | Deposit date: | 2001-10-10 | Release date: | 2002-02-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | RanGAP mediates GTP hydrolysis without an arginine finger. Nature, 415, 2002
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1K8R
| Crystal structure of Ras-Bry2RBD complex | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein kinase byr2, ... | Authors: | Scheffzek, K, Gruenewald, P, Wohlgemuth, S, Kabsch, W, Tu, H, Wigler, M, Wittinghofer, A, Herrmann, C. | Deposit date: | 2001-10-25 | Release date: | 2002-03-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Ras-Byr2RBD complex: structural basis for Ras effector recognition in yeast. Structure, 9, 2001
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1KZ7
| Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42 | Descriptor: | CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS | Authors: | Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. | Deposit date: | 2002-02-06 | Release date: | 2002-03-20 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
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1KZG
| DbsCdc42(Y889F) | Descriptor: | CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS | Authors: | Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J. | Deposit date: | 2002-02-06 | Release date: | 2002-03-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J., 21, 2002
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1GWN
| The crystal structure of the core domain of RhoE/Rnd3 - a constitutively activated small G protein | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rho-related GTP-binding protein RhoE | Authors: | Garavini, H, Riento, K, Phelan, J.P, McAlister, M.S.B, Ridley, A.J, Keep, N.H. | Deposit date: | 2002-03-19 | Release date: | 2002-04-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Core Domain of Rhoe/Rnd3: A Constitutively Activated Small G Protein Biochemistry, 41, 2002
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1KI1
| Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42 | Descriptor: | G25K GTP-binding protein, placental isoform, SULFATE ION, ... | Authors: | Snyder, J.T, Pruitt, W.M, Der, C.J, Sondek, J. | Deposit date: | 2001-12-02 | Release date: | 2002-05-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9, 2002
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1LB1
| Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA | Descriptor: | Guanine nucleotide exchange factor DBS, Transforming protein RhoA | Authors: | Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J. | Deposit date: | 2002-04-01 | Release date: | 2002-05-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9, 2002
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1KY2
| GPPNHP-BOUND YPT7P AT 1.6 A RESOLUTION | Descriptor: | GTP-BINDING PROTEIN YPT7P, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Constantinescu, A.-T, Rak, A, Scheidig, A.J. | Deposit date: | 2002-02-02 | Release date: | 2002-06-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases. Structure, 10, 2002
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1KY3
| GDP-BOUND YPT7P AT 1.35 A RESOLUTION | Descriptor: | GTP-BINDING PROTEIN YPT7P, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Constantinescu, A.-T, Rak, A, Scheidig, A.J. | Deposit date: | 2002-02-02 | Release date: | 2002-06-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Rab-subfamily-specific regions of Ypt7p are structurally different from other RabGTPases. Structure, 10, 2002
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1M7B
| Crystal structure of Rnd3/RhoE: functional implications | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rnd3/RhoE small GTP-binding protein | Authors: | Fiegen, D, Blumenstein, L, Stege, P, Vetter, I.R, Ahmadian, M.R. | Deposit date: | 2002-07-19 | Release date: | 2002-08-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Rnd3/RhoE: functional implications FEBS LETT., 525, 2002
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1GZS
| CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE GEF DOMAIN OF THE SALMONELLA TYPHIMURIUM SOPE TOXIN AND HUMAN Cdc42 | Descriptor: | GTP-BINDING PROTEIN, SOPE, SULFATE ION | Authors: | Buchwald, G, Friebel, A, Galan, J.E, Hardt, W.D, Wittinghofer, A, Scheffzek, K. | Deposit date: | 2002-06-05 | Release date: | 2002-09-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for the Reversible Activation of a Rho Protein by the Bacterial Toxin Sope Embo J., 21, 2002
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1LF5
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1LF0
| Crystal Structure of RasA59G in the GTP-bound form | Descriptor: | CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Hall, B.E, Bar-Sagi, D, Nassar, N. | Deposit date: | 2002-04-10 | Release date: | 2002-11-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structural Basis for the Transition from Ras-GTP to Ras-GDP Proc.Natl.Acad.Sci.USA, 99, 2002
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1N6R
| Crystal Structure of Human Rab5a A30L mutant complex with GppNHp | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | Deposit date: | 2002-11-11 | Release date: | 2002-11-27 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6H
| Crystal Structure of Human Rab5a | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | Deposit date: | 2002-11-11 | Release date: | 2002-11-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6I
| Crystal Structure of Human Rab5a A30P mutant Complex with GDP | Descriptor: | BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | Deposit date: | 2002-11-11 | Release date: | 2002-11-27 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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1N6K
| Crystal Structure of Human Rab5a A30P mutant complex with GDP and aluminum fluoride | Descriptor: | ALUMINUM FLUORIDE, BETA-MERCAPTOETHANOL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Zhu, G, Liu, J, Terzyan, S, Zhai, P, Li, G, Zhang, X.C. | Deposit date: | 2002-11-11 | Release date: | 2002-11-27 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | High Resolution Crystal Structures of Human Rab5a and Five Mutants with Substitutions in the Catalytically Important Phosphate-Binding Loop J.Biol.Chem., 278, 2003
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