4FME
 
 | | EspG-Rab1-Arf6 complex | | Descriptor: | ADP-ribosylation factor 6, ALUMINUM FLUORIDE, EspG protein, ... | | Authors: | Shao, F, Zhu, Y. | | Deposit date: | 2012-06-16 | | Release date: | 2012-09-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
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3VHX
 | | The crystal structure of Arf6-MKLP1 (Mitotic kinesin-like protein 1) complex | | Descriptor: | ADP-ribosylation factor 6, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Makyio, H, Takei, T, Ohgi, H, Takahashi, S, Takatsu, H, Ueda, T, Kanaho, Y, Xie, Y, Shin, H.W, Kamikubo, H, Kataoka, M, Kawasaki, M, Kato, R, Wakatsuki, S, Nakayama, K. | | Deposit date: | 2011-09-12 | | Release date: | 2012-05-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis
Embo J., 31, 2012
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7URO
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8BSH
 | | COPII inner coat | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein transport protein SEC23, ... | | Authors: | Zanetti, G, Pyle, E.W. | | Deposit date: | 2022-11-25 | | Release date: | 2023-01-18 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0.
Elife, 11, 2022
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4Q66
 | | Structure of Exomer bound to Arf1. | | Descriptor: | ADP-ribosylation factor 1, Chs5p, MAGNESIUM ION, ... | | Authors: | Paczkowski, J.E, Fromme, J.C. | | Deposit date: | 2014-04-21 | | Release date: | 2014-09-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.354 Å) | | Cite: | Structural basis for membrane binding and remodeling by the exomer secretory vesicle cargo adaptor.
Dev.Cell, 30, 2014
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2QTV
 | | Structure of Sec23-Sar1 complexed with the active fragment of Sec31 | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein transport protein SEC23, ... | | Authors: | Goldberg, J, Bi, X, Mancias, J.D. | | Deposit date: | 2007-08-02 | | Release date: | 2008-01-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31.
Dev.Cell, 13, 2007
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7MGE
 | | Structure of C9orf72:SMCR8:WDR41 in complex with ARF1 | | Descriptor: | ADP-ribosylation factor 1, BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Su, M.-Y, Hurley, J.H. | | Deposit date: | 2021-04-12 | | Release date: | 2021-06-23 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Structural basis for the ARF GAP activity and specificity of the C9orf72 complex.
Nat Commun, 12, 2021
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7DN8
 | | Crystal structure of Salmonella effector SopF in complex with ARF1 | | Descriptor: | ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Ding, J, Shao, F. | | Deposit date: | 2020-12-09 | | Release date: | 2021-12-15 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.6084 Å) | | Cite: | ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy.
Nat.Struct.Mol.Biol., 29, 2022
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7DN9
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7UX3
 | | Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Hooy, R.M, Hurley, J.H. | | Deposit date: | 2022-05-04 | | Release date: | 2023-05-10 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (9.6 Å) | | Cite: | Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
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2W83
 | | Crystal structure of the ARF6 GTPase in complex with a specific effector, JIP4 | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, ADP-RIBOSYLATION FACTOR 6, C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4, ... | | Authors: | Isabet, T, Montagnac, G, Regazzoni, K, Raynal, B, El Khadali, F, Franco, M, England, P, Chavrier, P, Houdusse, A, Menetrey, J. | | Deposit date: | 2009-01-08 | | Release date: | 2009-07-14 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | The Structural Basis of Arf Effector Specificity: The Crystal Structure of Arf6 in a Complex with Jip4.
Embo J., 28, 2009
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3DOF
 | | Complex of ARL2 and BART, Crystal Form 2 | | Descriptor: | ADP-ribosylation factor-like protein 2, ADP-ribosylation factor-like protein 2-binding protein, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhang, T, Li, S, Ding, J. | | Deposit date: | 2008-07-04 | | Release date: | 2009-03-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector
Structure, 17, 2009
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7R4H
 | | phospho-STING binding to adaptor protein complex-1 | | Descriptor: | ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... | | Authors: | Xu, P, Ablasser, A. | | Deposit date: | 2022-02-08 | | Release date: | 2022-09-14 | | Last modified: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (2.34 Å) | | Cite: | Clathrin-associated AP-1 controls termination of STING signalling.
Nature, 610, 2022
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7OK7
 | | Crystal structure of the UNC119B ARL3 complex | | Descriptor: | 1,2-ETHANEDIOL, ADP-ribosylation factor-like protein 3, GLYCEROL, ... | | Authors: | Yelland, T, Ismail, S. | | Deposit date: | 2021-05-17 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms.
Biochemistry, 60, 2021
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4KAX
 | | Crystal structure of the Grp1 PH domain in complex with Arf6-GTP | | Descriptor: | ADP-ribosylation factor 6, CITRIC ACID, Cytohesin-3, ... | | Authors: | Lambright, D.G, Malaby, A.W, van den Berg, B. | | Deposit date: | 2013-04-23 | | Release date: | 2013-08-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3DOE
 | | Complex of ARL2 and BART, Crystal Form 1 | | Descriptor: | ADP-ribosylation factor-like protein 2, ADP-ribosylation factor-like protein 2-binding protein, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhang, T, Li, S, Ding, J. | | Deposit date: | 2008-07-04 | | Release date: | 2009-03-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector
Structure, 17, 2009
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6VBV
 | | Structure of the bovine BBSome:ARL6:GTP complex | | Descriptor: | ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ... | | Authors: | Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A. | | Deposit date: | 2019-12-19 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Elife, 9, 2020
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6FAE
 | | The Sec7 domain of IQSEC2 (Brag1) in complex with the small GTPase Arf1 | | Descriptor: | 1,2-ETHANEDIOL, ADP-ribosylation factor 1, IQ motif and SEC7 domain-containing protein 2 | | Authors: | Gray, J, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P, von Delft, F. | | Deposit date: | 2017-12-15 | | Release date: | 2018-01-17 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Targeting the Small GTPase Superfamily through their Regulatory Proteins.
Angew.Chem.Int.Ed.Engl., 2019
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6VOA
 | | Cryo-EM structure of the BBSome-ARL6 complex | | Descriptor: | ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ... | | Authors: | Yang, S, Walz, T, Nachury, M.V. | | Deposit date: | 2020-01-30 | | Release date: | 2020-06-24 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes.
Elife, 9, 2020
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5EE5
 | | Structure of human ARL1 in complex with the DCB domain of BIG1 | | Descriptor: | ACETATE ION, ADP-ribosylation factor-like protein 1, Brefeldin A-inhibited guanine nucleotide-exchange protein 1, ... | | Authors: | Galindo, A, Soler, N, Munro, S. | | Deposit date: | 2015-10-22 | | Release date: | 2016-07-06 | | Last modified: | 2016-07-27 | | Method: | X-RAY DIFFRACTION (2.279 Å) | | Cite: | Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi.
Cell Rep, 16, 2016
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6GNI
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3BH7
 | | Crystal structure of the RP2-Arl3 complex bound to GDP-AlF4 | | Descriptor: | ADP-ribosylation factor-like protein 3, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Veltel, S, Gasper, R, Wittinghofer, A. | | Deposit date: | 2007-11-28 | | Release date: | 2008-03-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3
Nat.Struct.Mol.Biol., 15, 2008
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3BH6
 | | Crystal structure of the RP2-Arl3 complex bound to GppNHp | | Descriptor: | ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Veltel, S, Gasper, R, Wittinghofer, A. | | Deposit date: | 2007-11-28 | | Release date: | 2008-03-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3
Nat.Struct.Mol.Biol., 15, 2008
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4BZI
 | | The structure of the COPII coat assembled on membranes | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SAR1P, ... | | Authors: | Zanetti, G, Prinz, S, Daum, S, Meister, A, Schekman, R, Bacia, K, Briggs, J.A.G. | | Deposit date: | 2013-07-26 | | Release date: | 2013-09-18 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (23 Å) | | Cite: | The Structure of the Copii Transport-Vesicle Coat Assembled on Membranes
Elife, 2, 2013
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4GOJ
 | | The Crystal Structure of full length Arl3GppNHp in complex with UNC119a | | Descriptor: | ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | Authors: | Ismail, S, Xiang-Chen, Y, Miertzschke, M, Vetter, I, Koerner, C, Wittinghofer, A. | | Deposit date: | 2012-08-20 | | Release date: | 2012-09-19 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119.
Embo J., 31, 2012
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