3J8I
 
 | | Near-Atomic Resolution for One State of F-Actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Galkin, V.E. | | Deposit date: | 2014-11-06 | | Release date: | 2015-01-14 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Near-atomic resolution for one state of f-actin.
Structure, 23, 2015
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5NBM
 | | Crystal structure of the Arp4-N-actin(ATP-state) heterodimer bound by a nanobody | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | | Authors: | Knoll, K.R, Eustermann, S, Hopfner, K.P. | | Deposit date: | 2017-03-02 | | Release date: | 2018-08-22 | | Last modified: | 2018-09-19 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling.
Nat. Struct. Mol. Biol., 25, 2018
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3QB0
 | | Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION | | Authors: | Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P. | | Deposit date: | 2011-01-12 | | Release date: | 2011-05-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.404 Å) | | Cite: | Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin.
Embo J., 30, 2011
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3M6G
 | | Crystal structure of actin in complex with lobophorolide | | Descriptor: | (1S,3S,4S,5S,7R,8S,9R,12E,14E,16R,17R,19R)-16-hydroxy-9-{(1S,2S,3S)-2-hydroxy-5-[(2S,4R,6S)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl]-1,3-dimethylpentyl}-3,5,7,17-tetramethoxy-8,14-dimethyl-11H-spiro[10,23-dioxabicyclo[17.3.1]tricosa-12,14,20-triene-4,2'-oxiran]-11-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Allingham, J.S. | | Deposit date: | 2010-03-15 | | Release date: | 2010-09-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Two molecules of lobophorolide cooperate to stabilize an actin dimer using both their "ring" and "tail" region.
Chem.Biol., 17, 2010
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3TPQ
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7K21
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7K20
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6FHL
 | | Cryo-EM structure of F-actin in complex with ADP-Pi | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2018-01-15 | | Release date: | 2018-06-13 | | Last modified: | 2018-08-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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3EL2
 | | Crystal Structure of Monomeric Actin Bound to Ca-ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION | | Authors: | Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. | | Deposit date: | 2008-09-19 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of monomeric actin bound to cytochalasin D.
J.Mol.Biol., 384, 2008
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1WUA
 | | The structure of Aplyronine A-actin complex | | Descriptor: | (8R,9R,10R,11R,14S,18S,20S,24S)-24-{(1R,2S,3R,6R,7R,8R,9S,10E)-8-(ACETYLOXY)-6-[(N,N-DIMETHYLALANYL)OXY]-11-[FORMYL(MET HYL)AMINO]-2-HYDROXY-1,3,7,9-TETRAMETHYLUNDEC-10-ENYL}-10-HYDROXY-14,20-DIMETHOXY-9,11,15,18-TETRAMETHYL-2-OXOOXACYCLOTE TRACOSA-3,5,15,21-TETRAEN-8-YL N,N,O-TRIMETHYLSERINATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Hirata, K, Muraoka, S, Suenaga, K, Kuroda, T, Kato, K, Tanaka, H, Yamamoto, M, Takata, M, Yamada, K, Kigoshi, H. | | Deposit date: | 2004-12-03 | | Release date: | 2006-02-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure basis for antitumor effect of aplyronine a
J.Mol.Biol., 356, 2006
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3EKS
 | | Crystal Structure of Monomeric Actin bound to Cytochalasin D | | Descriptor: | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, ... | | Authors: | Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. | | Deposit date: | 2008-09-19 | | Release date: | 2008-10-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of monomeric actin bound to cytochalasin D.
J.Mol.Biol., 384, 2008
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1YXQ
 | | Crystal structure of actin in complex with swinholide A | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Klenchin, V.A, King, R, Tanaka, J, Marriott, G, Rayment, I. | | Deposit date: | 2005-02-22 | | Release date: | 2005-05-17 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structural basis of swinholide a binding to actin
Chem.Biol., 12, 2005
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3G37
 | | Cryo-EM structure of actin filament in the presence of phosphate | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Wakabayshi, T, Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q. | | Deposit date: | 2009-02-02 | | Release date: | 2010-11-03 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
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3EKU
 | | Crystal Structure of Monomeric Actin bound to Cytochalasin D | | Descriptor: | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, ... | | Authors: | Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. | | Deposit date: | 2008-09-19 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of monomeric actin bound to cytochalasin D.
J.Mol.Biol., 384, 2008
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2A5X
 | | Crystal Structure of a Cross-linked Actin Dimer | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Actin, alpha skeletal muscle, ... | | Authors: | Kudryashov, D.S, Sawaya, M.R, Adisetiyo, H, Norcross, T, Hegyi, G, Reisler, E, Yeates, T.O. | | Deposit date: | 2005-07-01 | | Release date: | 2005-08-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2ASM
 | | Structure of Rabbit Actin In Complex With Reidispongiolide A | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Allingham, J.S, Zampella, A, D'Auria, M.V, Rayment, I. | | Deposit date: | 2005-08-23 | | Release date: | 2005-10-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2ASP
 | | Structure of Rabbit Actin In Complex With Reidispongiolide C | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Allingham, J.S, Zampella, A, D'Auria, M.V, Rayment, I. | | Deposit date: | 2005-08-23 | | Release date: | 2005-10-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2Y83
 | | Actin filament pointed end | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Narita, A, Oda, T, Maeda, Y. | | Deposit date: | 2011-02-02 | | Release date: | 2011-03-30 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (22.9 Å) | | Cite: | Structural Basis for the Slow Dynamics of the Actin Filament Pointed End.
Embo J., 30, 2011
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3B63
 | | Actin filament model in the extended form of acromsomal bundle in the Limulus sperm | | Descriptor: | Actin | | Authors: | Cong, Y, Topf, M, Sali, A, Matsudaira, P, Dougherty, M, Chiu, W, Schmid, M.F. | | Deposit date: | 2007-10-26 | | Release date: | 2008-11-18 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Crystallographic conformers of actin in a biologically active bundle of filaments.
J.Mol.Biol., 375, 2008
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3B5U
 | | Actin filament model from extended form of acromsomal bundle in the Limulus sperm | | Descriptor: | Actin, alpha skeletal muscle | | Authors: | Cong, Y, Topf, M, Sali, A, Matsudaira, P, Dougherty, M, Chiu, W, Schmid, M.F. | | Deposit date: | 2007-10-26 | | Release date: | 2008-04-15 | | Last modified: | 2024-02-21 | | Method: | ELECTRON CRYSTALLOGRAPHY (9.5 Å) | | Cite: | Crystallographic conformers of actin in a biologically active bundle of filaments
J.Mol.Biol., 375, 2008
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3BYH
 | | Model of actin-fimbrin ABD2 complex | | Descriptor: | Actin, fimbrin ABD2 | | Authors: | Galkin, V.E, Orlova, A, Cherepanova, O, Lebart, M.C, Egelman, E.H. | | Deposit date: | 2008-01-16 | | Release date: | 2008-02-19 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | High-resolution cryo-EM structure of the F-actin-fimbrin/plastin ABD2 complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2ZWH
 | | Model for the F-actin structure | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Oda, T, Iwasa, M, Aihara, T, Maeda, Y, Narita, A. | | Deposit date: | 2008-12-05 | | Release date: | 2009-01-20 | | Last modified: | 2017-10-11 | | Method: | FIBER DIFFRACTION (3.3 Å) | | Cite: | The nature of the globular- to fibrous-actin transition.
Nature, 457, 2009
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4CJ7
 | | Structure of Crenactin, an archeal actin-like protein | | Descriptor: | ACTIN/ACTIN FAMILY PROTEIN, ADENOSINE-5'-DIPHOSPHATE | | Authors: | Izore, T, Duman, R.E, Kureisaite-Ciziene, D, Lowe, J. | | Deposit date: | 2013-12-19 | | Release date: | 2014-01-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crenactin from Pyrobaculum Calidifontis is Closely Related to Actin in Structure and Forms Steep Helical Filaments.
FEBS Lett., 588, 2014
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7AHN
 | | Cryo-EM structure of F-actin stabilized by cis-optoJASP-8 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Raunser, S. | | Deposit date: | 2020-09-24 | | Release date: | 2021-01-27 | | Last modified: | 2021-04-14 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7AHQ
 | | Cryo-EM structure of F-actin stabilized by trans-optoJASP-8 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Pospich, S, Raunser, S. | | Deposit date: | 2020-09-25 | | Release date: | 2021-01-27 | | Last modified: | 2021-04-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
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