5NBM

Crystal structure of the Arp4-N-actin(ATP-state) heterodimer bound by a nanobody

Summary for 5NBM

• Entry DOI: 10.2210/pdb5nbm/pdb
• Related: 5NBL 5NBN
• Descriptor: Actin-related protein 4, Actin, nAct-Nanobody, ... (6 entities in total)
• Functional Keywords: chromatin remodeling, nanobody, ino80, swr1, nua4, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 8
• Total formula weight: 232724.89

Authors

Knoll, K.R.,Eustermann, S.,Hopfner, K.P. (deposition date: 2017-03-02, release date: 2018-08-22, Last modification date: 2018-09-19)

• Primary citation: Knoll, K.R.,Eustermann, S.,Niebauer, V.,Oberbeckmann, E.,Stoehr, G.,Schall, K.,Tosi, A.,Schwarz, M.,Buchfellner, A.,Korber, P.,Hopfner, K.P.; The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling.; Nat. Struct. Mol. Biol., 25:823-832, 2018; PubMed: 30177756; DOI: 10.1038/s41594-018-0115-8

Experimental method

X-RAY DIFFRACTION (3.4 Å)