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6TQE
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BU of 6tqe by Molmil
The structure of ABC transporter Rv1819c without addition of substrate
Descriptor: ABC transporter ATP-binding protein/permease, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Rempel, S, Gati, C, Slotboom, D.J, Guskov, A.
Deposit date:2019-12-16
Release date:2020-04-01
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
5KFY
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BU of 5kfy by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 4 degree
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
6IPX
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BU of 6ipx by Molmil
Crystal structure of the apo form transcription factor
Descriptor: AimR transcriptional regulator
Authors:Oy, S.Y, Zhen, X, Zhou, H, Ding, W.
Deposit date:2018-11-05
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Structural basis of AimP signaling molecule recognition by AimR in Spbeta group of bacteriophages.
Protein Cell, 10, 2019
6IS8
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BU of 6is8 by Molmil
Crystal structure of ZmMoc1 D115N mutant in complex with Holliday junction
Descriptor: DNA (33-MER), MAGNESIUM ION, Monokaryotic chloroplast 1, ...
Authors:Lin, Z, Lin, H, Zhang, D, Yuan, C.
Deposit date:2018-11-15
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
1K9B
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BU of 1k9b by Molmil
Crystal structure of the bifunctional soybean Bowman-Birk inhibitor at 0.28 nm resolution. Structural peculiarities in a folded protein conformation
Descriptor: BOWMAN-BIRK TYPE PROTEINASE INHIBITOR
Authors:Voss, R.H, Ermler, U, Essen, L.O, Wenzl, G, Kim, Y.M, Flecker, P.
Deposit date:2001-10-29
Release date:2001-11-16
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the bifunctional soybean Bowman-Birk inhibitor at 0.28-nm resolution. Structural peculiarities in a folded protein conformation.
Eur.J.Biochem., 242, 1996
6HCN
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BU of 6hcn by Molmil
Adenovirus Type 5 Fiber Knob protein at 1.49A resolution
Descriptor: 1,2-ETHANEDIOL, Fiber protein, MAGNESIUM ION
Authors:Rizkallah, P.J, Parker, A.L, Baker, A.T.
Deposit date:2018-08-15
Release date:2019-02-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions.
Nat Commun, 10, 2019
1QKJ
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BU of 1qkj by Molmil
T4 Phage B-Glucosyltransferase, Substrate Binding and Proposed Catalytic Mechanism
Descriptor: BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
Authors:Morera, S, Imberty, I, Aschke-Sonnenborn, U, Ruger, W, Freemont, P.S.
Deposit date:1999-07-22
Release date:1999-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:T4 Phage Beta-Glucosyltransferase: Substrate Binding and Proposed Catalytic Mechanism
J.Mol.Biol., 292, 1999
7AON
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BU of 7aon by Molmil
Crystal structure of CI2 double mutant L49I,I57V
Descriptor: GLYCEROL, SULFATE ION, Subtilisin-chymotrypsin inhibitor-2A
Authors:Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V.
Deposit date:2020-10-14
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.
Commun Biol, 4, 2021
7D8C
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BU of 7d8c by Molmil
Crystal structure of the Cas12i1-crRNA binary complex
Descriptor: 12i1, CITRIC ACID, RNA (3-MER), ...
Authors:Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y.
Deposit date:2020-10-07
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
6HSO
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BU of 6hso by Molmil
Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), ACETATE ION, ...
Authors:Kasaragod, V.B, Schindelin, H.
Deposit date:2018-10-01
Release date:2019-01-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Neuron, 101, 2019
6V1Z
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BU of 6v1z by Molmil
genome-containing AAVrh.39 particles
Descriptor: Capsid protein VP1, DNA (5'-D(*CP*A)-3')
Authors:Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2019-11-21
Release date:2019-12-11
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
5LMB
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BU of 5lmb by Molmil
HUMAN SPLEEN TYROSINE KINASE KINASE DOMAIN IN COMPLEX WITH AZANAPHTHYRIDINE INHIBITOR
Descriptor: 7-[6-(dimethylamino)pyridin-3-yl]-~{N}-[[(3~{S})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine, GLYCEROL, Tyrosine-protein kinase SYK
Authors:Somers, D.O, Neu, M.
Deposit date:2016-07-29
Release date:2016-09-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
4TVP
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BU of 4tvp by Molmil
Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level Definition of Pre-Fusion gp120 and gp41, in Complex with Human Antibodies PGT122 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ...
Authors:Pancera, M, Zhou, T, Kwong, P.D.
Deposit date:2014-06-27
Release date:2014-10-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
Nature, 514, 2014
2ZJK
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BU of 2zjk by Molmil
Crystal structure of the human BACE1 catalytic domain in complex with 4-(4-fluoro-benzyl)-piperazine-2-carboxylic acid(3-mercapto-propyl)-amide
Descriptor: (2S)-4-(4-fluorobenzyl)-N-(3-sulfanylpropyl)piperazine-2-carboxamide, Beta-secretase 1
Authors:Randal, M, Lam, M.B, Lu, W, Romanowski, M.J.
Deposit date:2008-03-07
Release date:2009-01-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Fragment-based discovery of novel BACE1 inhibitors using Tethering technology
To be Published
4TXT
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BU of 4txt by Molmil
Crystal Structure of a GH48 cellobiohydrolase from Caldicellulosiruptor bescii
Descriptor: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoside hydrolase family 48, ...
Authors:An, J, Feng, Y.
Deposit date:2014-07-07
Release date:2014-08-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallization and preliminary X-ray analysis of a processive cellobiohydrolase CbCBH48A from Caldicellulosiruptor bescii
To Be Published
4U05
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BU of 4u05 by Molmil
Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) S74A Variant
Descriptor: SULFATE ION, Single Domain Antibody
Authors:Legler, P.M.
Deposit date:2014-07-11
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and mutational analysis of a monomeric and dimeric form of a single domain antibody with implications for protein misfolding.
Proteins, 82, 2014
2ZND
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BU of 2znd by Molmil
Crystal structure of Ca2+-free form of des3-20ALG-2
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, PHOSPHATE ION, Programmed cell death protein 6, ...
Authors:Suzuki, H, Kawasaki, M, Inuzuka, T, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M.
Deposit date:2008-04-22
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
Structure, 16, 2008
7EIV
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BU of 7eiv by Molmil
heterotetrameric glycyl-tRNA synthetase from Escherichia coli
Descriptor: GLYCINE, Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, ...
Authors:Ju, Y, Zhou, H.
Deposit date:2021-03-31
Release date:2021-08-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications.
Nucleic Acids Res., 49, 2021
6V1T
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BU of 6v1t by Molmil
Empty AAVrh.39 particle
Descriptor: Capsid protein VP1
Authors:Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2019-11-21
Release date:2019-12-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
2IS4
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BU of 2is4 by Molmil
Crystal structure of UvrD-DNA-ADPNP ternary complex
Descriptor: 25-MER, DNA helicase II, MAGNESIUM ION, ...
Authors:Yang, W, Lee, J.Y.
Deposit date:2006-10-16
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
7AOK
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BU of 7aok by Molmil
Crystal structure of CI2 mutant L49I
Descriptor: SULFATE ION, Subtilisin-chymotrypsin inhibitor-2A
Authors:Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V.
Deposit date:2020-10-14
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.
Commun Biol, 4, 2021
1JN0
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BU of 1jn0 by Molmil
Crystal structure of the non-regulatory A4 isoform of spinach chloroplast glyceraldehyde-3-phosphate dehydrogenase complexed with NADP
Descriptor: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
Authors:Fermani, S, Ripamonti, A, Sabatino, P, Zanotti, G, Scagliarini, S, Sparla, F, Trost, P, Pupillo, P.
Deposit date:2001-07-21
Release date:2001-11-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the non-regulatory A(4 )isoform of spinach chloroplast glyceraldehyde-3-phosphate dehydrogenase complexed with NADP.
J.Mol.Biol., 314, 2001
7W5P
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BU of 7w5p by Molmil
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain bound to 12bp N6-methyldeoxyadenine (6mA) containing duplex DNA
Descriptor: CcTet, DNA, DNA (12-MER), ...
Authors:Mu, Y.J, Zhang, L, Zhang, L.
Deposit date:2021-11-30
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA.
Nat.Chem.Biol., 18, 2022
6TNH
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BU of 6tnh by Molmil
Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp, Magnesium at 2.21 Angstrom resolution
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ASPARTIC ACID, Adenylosuccinate synthetase, ...
Authors:Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A.
Deposit date:2019-12-08
Release date:2020-12-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes.
Science, 372, 2021
2ZJJ
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BU of 2zjj by Molmil
Crystal structure of the human BACE1 catalytic domain in complex with 4-(4-fluoro-benzyl)-piperazine-2-carboxylic acid (2-mercapto-ethyl)-amide
Descriptor: (2S)-4-(4-fluorobenzyl)-N-(2-sulfanylethyl)piperazine-2-carboxamide, Beta-secretase 1
Authors:Randal, M, Lam, M.B, Romanowski, M.J.
Deposit date:2008-03-07
Release date:2009-01-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Fragment-based discovery of novel BACE1 inhibitors using Tethering technology
To be Published

223532

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