2KI2
| Solution Structure of ss-DNA Binding Protein 12RNP2 Precursor, HP0827(O25501_HELPY) form Helicobacter pylori | Descriptor: | Ss-DNA binding protein 12RNP2 | Authors: | Ma, C, Lee, J, Kim, J, Park, S, Kwon, A, Lee, B. | Deposit date: | 2009-04-20 | Release date: | 2009-10-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site J.Biochem., 146, 2009
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2K91
| Enhancing the activity of insulin by stereospecific unfolding | Descriptor: | Insulin | Authors: | Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A. | Deposit date: | 2008-09-29 | Release date: | 2008-11-18 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS. J.Biol.Chem., 284, 2009
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2OKR
| Crystal Structure of the P38a-MAPKAP kinase 2 Heterodimer | Descriptor: | MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14 | Authors: | Ter Haar, E. | Deposit date: | 2007-01-17 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the P38alpha-MAPKAP kinase 2 heterodimer. J.Biol.Chem., 282, 2007
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2NRM
| S-nitrosylated blackfin tuna myoglobin | Descriptor: | GLYCEROL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Schreiter, E.R, Rodr guez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J. | Deposit date: | 2006-11-02 | Release date: | 2007-05-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | S-nitrosylation-induced conformational change in blackfin tuna myoglobin. J.Biol.Chem., 282, 2007
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2O3D
| Structure of human SF2/ASF RNA recognition motif 2 (RRM2) | Descriptor: | Splicing factor, arginine/serine-rich 1 | Authors: | Tintaru, A.M, Hautbergue, G.M, Hounslow, A.M, Lian, L.Y, Craven, C.J, Wilson, S.A. | Deposit date: | 2006-12-01 | Release date: | 2007-10-16 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structural and functional analysis of RNA and TAP binding to SF2/ASF. Embo Rep., 8, 2007
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2OAH
| Crystal Structure of Human Beta Secretase Complexed with inhibitor | Descriptor: | Beta-secretase 1, N-[(1S,2S)-2-AMINO-1-(3-THIENYLMETHYL)HEXYL]-2-({[(1S,2S)-2-METHYLCYCLOPROPYL]METHYL}AMINO)-6-[METHYL(METHYLSULFONYL)AMINO]ISONICOTINAMIDE | Authors: | Munshi, S. | Deposit date: | 2006-12-15 | Release date: | 2007-08-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation. Bioorg.Med.Chem.Lett., 17, 2007
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2O89
| S. aureus thioredoxin P31T/C32S mutant | Descriptor: | Thioredoxin | Authors: | Roos, G, Loris, R, Messens, J. | Deposit date: | 2006-12-12 | Release date: | 2007-07-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin J.Mol.Biol., 368, 2007
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2OAY
| Crystal structure of latent human C1-inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Plasma protease C1 inhibitor | Authors: | Harmat, V, Beinrohr, L, Gal, P, Dobo, J. | Deposit date: | 2006-12-18 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease J.Biol.Chem., 282, 2007
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2OCT
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2OE0
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2OFS
| Crystal structure of human CD59 | Descriptor: | CD59 glycoprotein | Authors: | Davies, C. | Deposit date: | 2007-01-04 | Release date: | 2007-05-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex. Acta Crystallogr.,Sect.D, 63, 2007
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2OIH
| Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ | Descriptor: | HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | Deposit date: | 2007-01-11 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
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2OHB
| Myoglobin cavity mutant I107W | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Phillips Jr, G.N, Schweers, R.L, Soman, J, Olson, J.S. | Deposit date: | 2007-01-09 | Release date: | 2007-01-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ligand pathways in myoglobin: A review of trp cavity mutations. Iubmb Life, 59, 2007
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2OJ3
| Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) | Descriptor: | COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | Deposit date: | 2007-01-12 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
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2OHL
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2NRL
| Blackfin tuna myoglobin | Descriptor: | 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Schreiter, E.R, Rodr guez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J. | Deposit date: | 2006-11-02 | Release date: | 2007-05-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (0.91 Å) | Cite: | S-nitrosylation-induced conformational change in blackfin tuna myoglobin. J.Biol.Chem., 282, 2007
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2NWG
| Structure of CXCL12:heparin disaccharide complex | Descriptor: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Stromal cell-derived factor 1 | Authors: | Murphy, J.W, Cho, Y, Lolis, E. | Deposit date: | 2006-11-14 | Release date: | 2007-02-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin J.Biol.Chem., 282, 2007
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2NWN
| New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1 | Descriptor: | Plasminogen activator, urokinase, upain-1 | Authors: | Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC) | Deposit date: | 2006-11-16 | Release date: | 2007-10-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1 J.Struct.Biol., 160, 2007
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2NZ4
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2O1N
| Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution | Descriptor: | Ala-Ile-Ala-Ser peptide, Phospholipase A2 VRV-PL-VIIIa | Authors: | Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | Deposit date: | 2006-11-29 | Release date: | 2006-12-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution To be Published
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2M51
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2MGI
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2M0C
| Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C | Descriptor: | Homeobox protein aristaless-like 4 | Authors: | Xu, X, Eletsky, A, Pulavarti, S, Lee, D, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-10-24 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C To be Published
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2MH3
| NMR structure of the basic helix-loop-helix region of the transcriptional repressor HES-1 | Descriptor: | Transcription factor HES-1 | Authors: | Wienk, H, Popovic, M, Coglievina, M, Boelens, R, Pongor, S, Pintar, A. | Deposit date: | 2013-11-15 | Release date: | 2014-02-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA. Proteins, 82, 2014
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2MHM
| Solution structure of cytochrome c Y67H | Descriptor: | Cytochrome c iso-1, HEME C | Authors: | Lan, W.X, Wang, Z.H, Yang, Z.Z, Ying, T.L, Wu, H.M, Tan, X.S, Cao, C.Y, Huang, Z.X. | Deposit date: | 2013-11-26 | Release date: | 2014-10-29 | Method: | SOLUTION NMR | Cite: | Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase Plos One, 9, 2014
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