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2KI2
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Solution Structure of ss-DNA Binding Protein 12RNP2 Precursor, HP0827(O25501_HELPY) form Helicobacter pylori
Descriptor: Ss-DNA binding protein 12RNP2
Authors:Ma, C, Lee, J, Kim, J, Park, S, Kwon, A, Lee, B.
Deposit date:2009-04-20
Release date:2009-10-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site
J.Biochem., 146, 2009
2K91
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Enhancing the activity of insulin by stereospecific unfolding
Descriptor: Insulin
Authors:Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A.
Deposit date:2008-09-29
Release date:2008-11-18
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS.
J.Biol.Chem., 284, 2009
2OKR
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BU of 2okr by Molmil
Crystal Structure of the P38a-MAPKAP kinase 2 Heterodimer
Descriptor: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14
Authors:Ter Haar, E.
Deposit date:2007-01-17
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the P38alpha-MAPKAP kinase 2 heterodimer.
J.Biol.Chem., 282, 2007
2NRM
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S-nitrosylated blackfin tuna myoglobin
Descriptor: GLYCEROL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schreiter, E.R, Rodr guez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J.
Deposit date:2006-11-02
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:S-nitrosylation-induced conformational change in blackfin tuna myoglobin.
J.Biol.Chem., 282, 2007
2O3D
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BU of 2o3d by Molmil
Structure of human SF2/ASF RNA recognition motif 2 (RRM2)
Descriptor: Splicing factor, arginine/serine-rich 1
Authors:Tintaru, A.M, Hautbergue, G.M, Hounslow, A.M, Lian, L.Y, Craven, C.J, Wilson, S.A.
Deposit date:2006-12-01
Release date:2007-10-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural and functional analysis of RNA and TAP binding to SF2/ASF.
Embo Rep., 8, 2007
2OAH
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BU of 2oah by Molmil
Crystal Structure of Human Beta Secretase Complexed with inhibitor
Descriptor: Beta-secretase 1, N-[(1S,2S)-2-AMINO-1-(3-THIENYLMETHYL)HEXYL]-2-({[(1S,2S)-2-METHYLCYCLOPROPYL]METHYL}AMINO)-6-[METHYL(METHYLSULFONYL)AMINO]ISONICOTINAMIDE
Authors:Munshi, S.
Deposit date:2006-12-15
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation.
Bioorg.Med.Chem.Lett., 17, 2007
2O89
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S. aureus thioredoxin P31T/C32S mutant
Descriptor: Thioredoxin
Authors:Roos, G, Loris, R, Messens, J.
Deposit date:2006-12-12
Release date:2007-07-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin
J.Mol.Biol., 368, 2007
2OAY
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BU of 2oay by Molmil
Crystal structure of latent human C1-inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Plasma protease C1 inhibitor
Authors:Harmat, V, Beinrohr, L, Gal, P, Dobo, J.
Deposit date:2006-12-18
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease
J.Biol.Chem., 282, 2007
2OCT
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Stefin B (Cystatin B) tetramer
Descriptor: Cystatin B
Authors:Jenko Kokalj, S, Guncar, G, Turk, D.
Deposit date:2006-12-21
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Essential role of proline isomerization in stefin B tetramer formation.
J.Mol.Biol., 366, 2007
2OE0
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Crystal Structure of Mitochondrial Thioredoxin 3 from Saccharomyces cerevisiae
Descriptor: Thioredoxin-3
Authors:Bao, R, Zhang, Y.R, Zhou, C.Z, Chen, Y.X.
Deposit date:2006-12-27
Release date:2008-01-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and mechanistic analyses of yeast mitochondrial thioredoxin Trx3 reveal putative function of its additional cysteine residues
Biochim.Biophys.Acta, 1794, 2009
2OFS
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Crystal structure of human CD59
Descriptor: CD59 glycoprotein
Authors:Davies, C.
Deposit date:2007-01-04
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex.
Acta Crystallogr.,Sect.D, 63, 2007
2OIH
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Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+
Descriptor: HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-11
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2OHB
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Myoglobin cavity mutant I107W
Descriptor: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Phillips Jr, G.N, Schweers, R.L, Soman, J, Olson, J.S.
Deposit date:2007-01-09
Release date:2007-01-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ligand pathways in myoglobin: A review of trp cavity mutations.
Iubmb Life, 59, 2007
2OJ3
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Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+)
Descriptor: COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ...
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-12
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2OHL
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BU of 2ohl by Molmil
X-ray crystal structure of beta secretase complexed with 2-aminoquinoline
Descriptor: Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ...
Authors:Patel, S.
Deposit date:2007-01-10
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Application of fragment screening by X-ray crystallography to beta-Secretase.
J.Med.Chem., 50, 2007
2NRL
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BU of 2nrl by Molmil
Blackfin tuna myoglobin
Descriptor: 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schreiter, E.R, Rodr guez, M.M, Weichsel, A, Montfort, W.R, Bonaventura, J.
Deposit date:2006-11-02
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (0.91 Å)
Cite:S-nitrosylation-induced conformational change in blackfin tuna myoglobin.
J.Biol.Chem., 282, 2007
2NWG
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BU of 2nwg by Molmil
Structure of CXCL12:heparin disaccharide complex
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Stromal cell-derived factor 1
Authors:Murphy, J.W, Cho, Y, Lolis, E.
Deposit date:2006-11-14
Release date:2007-02-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin
J.Biol.Chem., 282, 2007
2NWN
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New Pharmacophore for Serine Protease Inhibition Revealed by Crystal Structure of Human Urokinase-type Plasminogen Activator Complexed with a Cyclic Peptidyl Inhibitor, upain-1
Descriptor: Plasminogen activator, urokinase, upain-1
Authors:Zhao, G, Yuan, C, Wind, T, Andreasen, P.A, Huang, Z, Huang, M, Structural Genomics Consortium (SGC)
Deposit date:2006-11-16
Release date:2007-10-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis of specificity of a peptidyl urokinase inhibitor, upain-1
J.Struct.Biol., 160, 2007
2NZ4
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Structural investigation of the GlmS ribozyme bound to its catalytic cofactor
Descriptor: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GlmS ribozyme, MAGNESIUM ION, ...
Authors:Cochrane, J.C.
Deposit date:2006-11-22
Release date:2007-01-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structural Investigation of the GlmS Ribozyme Bound to Its Catalytic Cofactor
Chem.Biol., 14, 2007
2O1N
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Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution
Descriptor: Ala-Ile-Ala-Ser peptide, Phospholipase A2 VRV-PL-VIIIa
Authors:Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2006-11-29
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution
To be Published
2M51
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BU of 2m51 by Molmil
NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1
Descriptor: Ras GTPase-activating protein 1
Authors:Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-02-12
Release date:2013-03-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1
To be Published
2MGI
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BU of 2mgi by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURES OF FIVE DISTAL HISTIDINE MUTANTS OF SPERM WHALE MYOGLOBIN
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Quillin, M.L, Arduini, R.M, Phillips Jr, G.N.
Deposit date:1993-05-10
Release date:1994-01-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution crystal structures of distal histidine mutants of sperm whale myoglobin.
J.Mol.Biol., 234, 1993
2M0C
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BU of 2m0c by Molmil
Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C
Descriptor: Homeobox protein aristaless-like 4
Authors:Xu, X, Eletsky, A, Pulavarti, S, Lee, D, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-10-24
Release date:2012-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C
To be Published
2MH3
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NMR structure of the basic helix-loop-helix region of the transcriptional repressor HES-1
Descriptor: Transcription factor HES-1
Authors:Wienk, H, Popovic, M, Coglievina, M, Boelens, R, Pongor, S, Pintar, A.
Deposit date:2013-11-15
Release date:2014-02-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA.
Proteins, 82, 2014
2MHM
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Solution structure of cytochrome c Y67H
Descriptor: Cytochrome c iso-1, HEME C
Authors:Lan, W.X, Wang, Z.H, Yang, Z.Z, Ying, T.L, Wu, H.M, Tan, X.S, Cao, C.Y, Huang, Z.X.
Deposit date:2013-11-26
Release date:2014-10-29
Method:SOLUTION NMR
Cite:Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase
Plos One, 9, 2014

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