6U85
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4XQZ
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![BU of 4xqz by Molmil](/molmil-images/mine/4xqz) | Calcium(II) and copper(II) bound to the Z-DNA form of d(CGCGCG), complexed by chloride and MES | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Rohner, M, Medina-Molner, A, Spingler, B. | Deposit date: | 2015-01-20 | Release date: | 2016-01-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | N,N,O and N,O,N Meridional cis Coordination of Two Guanines to Copper(II) by d(CGCGCG)2. Inorg.Chem., 55, 2016
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6AEA
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![BU of 6aea by Molmil](/molmil-images/mine/6aea) | Crystal Structure of HEWL in complex with TEMED (in the aroma form) after 5 hours under fibrillation conditions | Descriptor: | CHLORIDE ION, Lysozyme C, N,N,N',N'-tetramethylethane-1,2-diamine, ... | Authors: | Seraj, Z, Seyedarabi, A. | Deposit date: | 2018-08-04 | Release date: | 2019-08-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The aroma of TEMED as an activation and stabilizing signal for the antibacterial enzyme HEWL. Plos One, 15, 2020
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2N4I
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![BU of 2n4i by Molmil](/molmil-images/mine/2n4i) | The solution structure of Skint-1, a critical determinant of dendritic epidermal gamma-delta T cell selection | Descriptor: | Selection and upkeep of intraepithelial T-cells protein 1 | Authors: | Salim, M, Knowles, T.J, Hart, R, Mohammed, F, Woodward, M.J, Willcox, C.R, Overduin, M, Hayday, A.C, Willcox, B.E. | Deposit date: | 2015-06-18 | Release date: | 2016-03-02 | Last modified: | 2016-05-11 | Method: | SOLUTION NMR | Cite: | Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection. J.Biol.Chem., 291, 2016
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2YLK
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![BU of 2ylk by Molmil](/molmil-images/mine/2ylk) | Carbohydrate-binding module CBM3b from the cellulosomal cellobiohydrolase 9A from Clostridium thermocellum | Descriptor: | CELLULOSE 1,4-BETA-CELLOBIOSIDASE | Authors: | Yaniv, O, Petkun, S, Shimon, L.J.W, Bayer, E.A, Lamed, R, Frolow, F. | Deposit date: | 2011-06-02 | Release date: | 2012-04-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Single Mutation Reforms the Binding Activity of an Adhesion-Deficient Family 3 Carbohydrate-Binding Module Acta Crystallogr.,Sect.D, 68, 2012
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3RCF
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![BU of 3rcf by Molmil](/molmil-images/mine/3rcf) | Human cyclophilin D complexed with N-[(4-aminophenyl)sulfonyl]benzamide | Descriptor: | N-[(4-aminophenyl)sulfonyl]benzamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-31 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RCL
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![BU of 3rcl by Molmil](/molmil-images/mine/3rcl) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 3-(1,3-oxazol-5-yl)aniline, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-31 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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8FW2
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![BU of 8fw2 by Molmil](/molmil-images/mine/8fw2) | Cryo-EM structure of full-length human NLRC4 inflammasome with C11 symmetry | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S. | Deposit date: | 2023-01-20 | Release date: | 2024-01-03 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing. Nat.Struct.Mol.Biol., 31, 2024
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8FW9
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![BU of 8fw9 by Molmil](/molmil-images/mine/8fw9) | Cryo-EM structure of full-length human NLRC4 inflammasome with C12 symmetry | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S. | Deposit date: | 2023-01-20 | Release date: | 2024-01-03 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (4.46 Å) | Cite: | Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing. Nat.Struct.Mol.Biol., 31, 2024
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3D1B
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![BU of 3d1b by Molmil](/molmil-images/mine/3d1b) | Tetragonal crystal structure of Tas3 C-terminal alpha motif | Descriptor: | RNA-induced transcriptional silencing complex protein tas3 | Authors: | Li, H, Patel, D.J. | Deposit date: | 2008-05-05 | Release date: | 2009-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Mol.Cell, 34, 2009
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3R49
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![BU of 3r49 by Molmil](/molmil-images/mine/3r49) | Human cyclophilin D complexed with quinolin-8-amine | Descriptor: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, quinolin-8-amine | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-17 | Release date: | 2012-03-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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6T3O
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![BU of 6t3o by Molmil](/molmil-images/mine/6t3o) | Crystal structure of the human myomesin domain 10 | Descriptor: | AZIDE ION, Myomesin-1 | Authors: | Duskova, J, Petrokova, H, Maly, P. | Deposit date: | 2019-10-11 | Release date: | 2021-03-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Myomedin scaffold variants targeted to 10E8 HIV-1 broadly neutralizing antibody mimic gp41 epitope and elicit HIV-1 virus-neutralizing sera in mice. Virulence, 12, 2021
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3RD9
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![BU of 3rd9 by Molmil](/molmil-images/mine/3rd9) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 3-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide, DI(HYDROXYETHYL)ETHER, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-04-01 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3R59
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![BU of 3r59 by Molmil](/molmil-images/mine/3r59) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 1-(3-aminophenyl)ethanone, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-18 | Release date: | 2012-03-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RDA
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![BU of 3rda by Molmil](/molmil-images/mine/3rda) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 3-methyl-1,2-oxazol-5-amine, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-04-01 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RDB
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![BU of 3rdb by Molmil](/molmil-images/mine/3rdb) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 3-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]aniline, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-04-01 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3R56
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![BU of 3r56 by Molmil](/molmil-images/mine/3r56) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 1H-indazol-6-amine, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-18 | Release date: | 2012-03-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3ADF
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![BU of 3adf by Molmil](/molmil-images/mine/3adf) | Crystal structure of a monomeric green fluorescent protein, Azami-Green (mAG) | Descriptor: | Monomeric Azami Green | Authors: | Ebisawa, T, Yamamura, A, Kameda, Y, Hayakawa, K, Nagata, K, Tanokura, M. | Deposit date: | 2010-01-20 | Release date: | 2010-05-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of mAG, a monomeric mutant of the green fluorescent protein Azami-Green, reveals the structural basis of its stable green emission Acta Crystallogr.,Sect.F, 66, 2010
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3R54
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![BU of 3r54 by Molmil](/molmil-images/mine/3r54) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, pyrrolidine-1-carbaldehyde | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-18 | Release date: | 2012-03-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RCK
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![BU of 3rck by Molmil](/molmil-images/mine/3rck) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, piperazine-1-carbaldehyde | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-31 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RCI
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![BU of 3rci by Molmil](/molmil-images/mine/3rci) | Human cyclophilin D complexed with 5-methyl-1,2-oxazol-3-amine | Descriptor: | 5-methyl-1,2-oxazol-3-amine, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-31 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3RCG
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![BU of 3rcg by Molmil](/molmil-images/mine/3rcg) | Human cyclophilin D complexed with dimethylformamide | Descriptor: | CHLORIDE ION, DIMETHYLFORMAMIDE, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-31 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3D1D
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![BU of 3d1d by Molmil](/molmil-images/mine/3d1d) | Hexagonal crystal structure of Tas3 C-terminal alpha motif | Descriptor: | RNA-induced transcriptional silencing complex protein tas3 | Authors: | Li, H, Patel, D.J. | Deposit date: | 2008-05-05 | Release date: | 2009-04-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Mol.Cell, 34, 2009
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1MCT
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![BU of 1mct by Molmil](/molmil-images/mine/1mct) | THE REFINED 1.6 ANGSTROMS RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PORCINE BETA-TRYPSIN AND MCTI-A, A TRYPSIN INHIBITOR OF SQUASH FAMILY | Descriptor: | BETA-TRYPSIN, CALCIUM ION, TRYPSIN INHIBITOR A | Authors: | Huang, Q, Liu, S, Tang, Y. | Deposit date: | 1992-10-24 | Release date: | 1994-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Refined 1.6 A resolution crystal structure of the complex formed between porcine beta-trypsin and MCTI-A, a trypsin inhibitor of the squash family. Detailed comparison with bovine beta-trypsin and its complex. J.Mol.Biol., 229, 1993
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2M7P
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![BU of 2m7p by Molmil](/molmil-images/mine/2m7p) | RXFP1 utilises hydrophobic moieties on a signalling surface of the LDLa module to mediate receptor activation | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor, Relaxin receptor 1 | Authors: | Kong, R.CK, Petrie, E.J, Mohanty, B, Ling, J, Lee, J.C.Y, Gooley, P.R, Bathgate, R.A.D. | Deposit date: | 2013-04-29 | Release date: | 2013-08-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation. J.Biol.Chem., 288, 2013
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