PDB: 52540 resultsInfo pagesStatus searchChemie searchBIRD

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4I2C	Ternary complex of mouse TdT with ssDNA and AMPcPP Descriptor: 5'-D(*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... Authors: Gouge, J, Delarue, M. Deposit date: 2012-11-21 Release date: 2013-07-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
8A3Q	Human Plasma Kallekrein in complex with 14W Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma kallikrein, ... Authors: McEwan, P.A. Deposit date: 2022-06-08 Release date: 2022-11-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema. J.Med.Chem., 65, 2022
8GT4	Crystal structure of human cardiac alpha actin Q137A mutant (AMPPNP state) in complex with fragmin F1 domain Descriptor: 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... Authors: Iwasa, M, Oda, T, Takeda, S. Deposit date: 2022-09-07 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
8GSW	Crystal structure of human cardiac alpha actin A108G mutant (AMPPNP state) in complex with fragmin F1 domain Descriptor: 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... Authors: Iwasa, M, Oda, T, Takeda, S. Deposit date: 2022-09-07 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
8GT2	Crystal structure of human cardiac alpha actin P109A mutant (AMPPNP state) in complex with fragmin F1 domain Descriptor: 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... Authors: Iwasa, M, Oda, T, Takeda, S. Deposit date: 2022-09-07 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
4IQT	Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid Descriptor: 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase Authors: Gouge, J, Delarue, M. Deposit date: 2013-01-13 Release date: 2013-09-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
4IQU	Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid Descriptor: (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, SODIUM ION Authors: Gouge, J, Delarue, M. Deposit date: 2013-01-13 Release date: 2013-09-04 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
4IQV	Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA Descriptor: 5'-D(*GP*CP*CP*G)-3', 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, ... Authors: Gouge, J, Delarue, M. Deposit date: 2013-01-13 Release date: 2013-09-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
4IQW	Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA Descriptor: (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, 5'-D(*GP*CP*CP*G)-3', DNA nucleotidylexotransferase, ... Authors: Gouge, J, Delarue, M. Deposit date: 2013-01-13 Release date: 2013-09-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
5UEI	Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 (Apo) Descriptor: CHLORIDE ION, GLYCEROL, O13 Authors: Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Herrin, B.R, Cooper, M.D, Wilson, I.A. Deposit date: 2017-01-02 Release date: 2017-10-18 Last modified: 2019-12-11 Method: X-RAY DIFFRACTION (1.702 Å) Cite: Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure, 25, 2017
3HQD	Human kinesin Eg5 motor domain in complex with AMPPNP and Mg2+ Descriptor: Kinesin-like protein KIF11, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Parke, C.L, Wojcik, E.J, Kim, S, Worthylake, D.K. Deposit date: 2009-06-05 Release date: 2009-12-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.19 Å) Cite: ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism. J.Biol.Chem., 285, 2010
5TJG	Thermus aquaticus delta1.1-sigmaA holoenzyme/downstream-fork promoter complex with an open clamp Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*A)-3'), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Darst, S.A, Bae, B. Deposit date: 2016-10-04 Release date: 2017-06-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: RNA polymerase motions during promoter melting. Science, 356, 2017
4I2H	Ternary complex of mouse TdT with ssDNA and AMPcPP Descriptor: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... Authors: Gouge, J, Delarue, M. Deposit date: 2012-11-21 Release date: 2013-07-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
3N8L	Crystal Structure of BlaC-E166A covalently bound with Ampicillin Descriptor: (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase, PHOSPHATE ION Authors: Tremblay, L.W, Blanchard, J.S. Deposit date: 2010-05-28 Release date: 2011-12-14 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structures of BlaC-E166A covalently bound to beta-lactams from all classes. To be Published
4JGE	Crystal structure of red fluorescent gene-engineered variant with improved folding - lanRFP_delS83 (Branchiostoma lanceolatum) Descriptor: GLYCEROL, Red fluorescent protein blFP-R5 Authors: Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V. Deposit date: 2013-03-01 Release date: 2013-09-18 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Structure of the red fluorescent protein from a lancelet (Branchiostoma lanceolatum): a novel GYG chromophore covalently bound to a nearby tyrosine. Acta Crystallogr.,Sect.D, 69, 2013
4JLK	Human dCK C4S-S74E mutant in complex with UDP and the F2.2.1 inhibitoR (2-[({2-[3-(2-FLUOROETHOXY)-4-METHOXYPHENYL]-5-METHYL-1,3-THIAZOL-4-YL}METHYL)SULFANYL]PYRIMIDINE-4,6-DIAMINE) Descriptor: 2-[({2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-methyl-1,3-thiazol-4-yl}methyl)sulfanyl]pyrimidine-4,6-diamine, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE Authors: Nomme, J, Lavie, A. Deposit date: 2013-03-12 Release date: 2013-09-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. J.Med.Chem., 56, 2013
3QQC	Crystal structure of archaeal Spt4/5 bound to the RNAP clamp domain Descriptor: DNA-directed RNA polymerase subunit b, DNA-directed RNA polymerase subunit a', DNA-directed RNA polymerase subunit A'', ... Authors: Martinez-Rucobo, F.W. Deposit date: 2011-02-15 Release date: 2011-03-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity. Embo J., 30, 2011
4JEO	Crystal structure of red fluorescent protein lanRFPdam exposed to prolonged X-ray irradiation Descriptor: GLYCEROL, Red fluorescent protein blFP-R5 Authors: Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V. Deposit date: 2013-02-27 Release date: 2013-09-18 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure of the red fluorescent protein from a lancelet (Branchiostoma lanceolatum): a novel GYG chromophore covalently bound to a nearby tyrosine. Acta Crystallogr.,Sect.D, 69, 2013
4JF9	Crystal structure of the wild type red fluorescent protein lanRFP (Branchiostoma Lanceolatum) Descriptor: Red fluorescent protein blFP-R5 Authors: Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V. Deposit date: 2013-02-28 Release date: 2013-09-18 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Structure of the red fluorescent protein from a lancelet (Branchiostoma lanceolatum): a novel GYG chromophore covalently bound to a nearby tyrosine. Acta Crystallogr.,Sect.D, 69, 2013
7SFA	Branchiostoma floridae fluorescent protein LanFP10A2 Descriptor: Fluorescent protein lanFP10A2 Authors: Pletnev, S, Pletneva, N, Pletnev, V.Z, Muslinkina, L. Deposit date: 2021-10-03 Release date: 2022-03-30 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.65 Å) Cite: A novel violet fluorescent protein contains a unique oxidized tyrosine as the simplest chromophore ever reported in fluorescent proteins. Protein Sci., 31, 2022
7SF9	Branchiostoma Floridae Violet Fluorescent Protein Descriptor: Violet Fluorescent Protein Authors: Pletnev, S, Pletneva, N, Pletnev, V.Z, Muslinkina, L. Deposit date: 2021-10-03 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A novel violet fluorescent protein contains a unique oxidized tyrosine as the simplest chromophore ever reported in fluorescent proteins. Protein Sci., 31, 2022
7RZZ	Crystal structure of FBF-2 in complex with LST-1 site A peptide and compact FBE RNA Descriptor: Fem-3 mRNA-binding factor 2, Lateral Signaling Target, RNA Authors: Qiu, C, Hall, T.M.T. Deposit date: 2021-08-28 Release date: 2022-04-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal. Nucleic Acids Res., 50, 2022
7RYN	CD1a-sulfatide-gdTCR complex Descriptor: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wegrecki, M, Le Nours, J, Rossjohn, J. Deposit date: 2021-08-25 Release date: 2022-05-18 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
7RYM	CD1a-endo-gdTCR complex Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... Authors: Wegrecki, M, Le Nours, J, Rossjohn, J. Deposit date: 2021-08-25 Release date: 2022-05-18 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
7RYO	CD1a-dideoxymycobactin-gdTCR complex Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, SULFATE ION, ... Authors: Wegrecki, M, Le Nours, J, Rossjohn, J. Deposit date: 2021-08-25 Release date: 2022-05-18 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3 Å) Cite: Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022

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