8TLO
 
 | | Crystal Structure Analysis of BCL11A in complex with DNA | | Descriptor: | B-cell lymphoma/leukemia 11A, DNA (5'-D(P*CP*GP*AP*CP*CP*GP*CP*AP*TP*TP*GP*GP*TP*CP*AP*AP*GP*CP*G)-3'), DNA (5'-D(P*GP*CP*TP*TP*GP*AP*CP*CP*AP*AP*TP*GP*CP*GP*GP*TP*CP*GP*C)-3'), ... | | Authors: | Seo, H.-S, Dhe-Paganon, S. | | Deposit date: | 2023-07-27 | | Release date: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | Crystal Structure Analysis of BCL11A in complex with DNA
To Be Published
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6W8V
 | | Crystal structure of mouse DNMT1 in complex with ACG DNA | | Descriptor: | ACG DNA (5'-D(*AP*CP*TP*TP*AP*(C49)P*GP*GP*AP*AP*GP*G)-3'), ACG DNA (5'-D(*CP*CP*TP*TP*CP*(5CM)P*GP*TP*AP*AP*GP*T)-3'), DNA (cytosine-5)-methyltransferase 1, ... | | Authors: | Anteneh, H, Song, J. | | Deposit date: | 2020-03-21 | | Release date: | 2020-07-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.12 Å) | | Cite: | DNMT1 activity, base flipping mechanism and genome-wide DNA methylation are regulated by the DNA sequence context
Nat Commun, 2020
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5G34
 | | Structure of Rad14 in complex with acetylaminoanthracene-C8-guanine containing DNA | | Descriptor: | 5'-D(*GP*CP*TP*CP*TP*AP*6FKP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', RAD14, ... | | Authors: | Simon, N, Ebert, C, Schneider, S. | | Deposit date: | 2016-04-18 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
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1FV7
 | | A TWO B-Z JUNCTION CONTAINING DNA RESOLVES INTO AN ALL RIGHT HANDED DOUBLE HELIX | | Descriptor: | 5'-D(*(5CM)P*GP*(5CM)P*GP*(0DC)P*(0DG)P*(5CM)P*GP*(5CM)P*G)-3' | | Authors: | Mauffret, O, El Amri, C, Santamaria, F, Tevanian, G, Rayner, B, Fermandjian, S. | | Deposit date: | 2000-09-19 | | Release date: | 2000-10-11 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A two B-Z junction containing DNA resolves into an all right-handed double-helix.
Nucleic Acids Res., 28, 2000
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5H8C
 | | Truncated XPD | | Descriptor: | IRON/SULFUR CLUSTER, XPD/Rad3 related DNA helicase | | Authors: | Naismith, J.H, Constantinescu, D. | | Deposit date: | 2015-12-23 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Mechanism of DNA loading by the DNA repair helicase XPD.
Nucleic Acids Res., 44, 2016
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5H8W
 | | XPD mechanism | | Descriptor: | ATP-dependent DNA helicase Ta0057, DNA (5'-D(P*TP*AP*CP*GP*A)-3'), IRON/SULFUR CLUSTER, ... | | Authors: | Naismith, J.H, Constantinescu, D. | | Deposit date: | 2015-12-24 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism of DNA loading by the DNA repair helicase XPD.
Nucleic Acids Res., 44, 2016
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8W09
 | | HIV-1 wild-type intasome core | | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, Integrase, MAGNESIUM ION, ... | | Authors: | Li, M, Craigie, R. | | Deposit date: | 2024-02-13 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro.
J.Mol.Biol., 436, 2024
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4J2I
 | | Multiple crystal structures of an all-AT DNA dodecamer stabilized by weak interactions | | Descriptor: | 5'-D(*AP*AP*TP*AP*AP*AP*TP*TP*TP*AP*TP*T)-3' | | Authors: | Acosta-Reyes, F.J, Subirana, J.A, Pous, J, Sanchez, R, Condom, N, Baldini, R, Malinina, L, Campos, J.L. | | Deposit date: | 2013-02-04 | | Release date: | 2014-02-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Polymorphic crystal structures of an all-AT DNA dodecamer.
Biopolymers, 103, 2015
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5G35
 | | Structure of Rad14 in complex with acetylaminopyren-C8-guanine containing DNA | | Descriptor: | 5'-D(*GP*CP*TP*CP*TP*AP*8PYP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', RAD14, ... | | Authors: | Simon, N, Ebert, C, Schneider, S. | | Deposit date: | 2016-04-18 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
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5G33
 | | Structure of Rad14 in complex with acetylnaphtyl-guanine containing DNA | | Descriptor: | 5'-D(*GP*CP*TP*CP*TP*AP*MFOP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', RAD14, ... | | Authors: | Simon, N, Ebert, C, Schneider, S. | | Deposit date: | 2016-04-18 | | Release date: | 2016-06-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
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3TBL
 | | Structure of Mono-ubiquitinated PCNA: Implications for DNA Polymerase Switching and Okazaki Fragment Maturation | | Descriptor: | Proliferating cell nuclear antigen, Ubiquitin | | Authors: | Zhang, Z, Lee, M, Lee, E, Zhang, S. | | Deposit date: | 2011-08-07 | | Release date: | 2012-05-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.903 Å) | | Cite: | Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation.
Cell Cycle, 11, 2012
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1QK9
 | | The solution structure of the domain from MeCP2 that binds to methylated DNA | | Descriptor: | METHYL-CPG-BINDING PROTEIN 2 | | Authors: | Wakefield, R.I.D, Smith, B.O, Nan, X, Free, A, Soteriou, A, Uhrin, D, Bird, A.P, Barlow, P.N. | | Deposit date: | 1999-07-12 | | Release date: | 1999-10-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The Solution Structure of the Domain from Mecp2 that Binds to Methylated DNA
J.Mol.Biol., 291, 1999
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6U91
 | | Crystal structure of DNMT3B(Q772R)-DNMT3L in complex with CpGpT DNA | | Descriptor: | CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | | Authors: | Gao, L, Song, J. | | Deposit date: | 2019-09-06 | | Release date: | 2020-06-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.99998879 Å) | | Cite: | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
To Be Published
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3QN2
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5G32
 | | Structure of Rad14 in complex with acetylaminophenyl-guanine containing DNA | | Descriptor: | 5'-D(*GP*CP*TP*CP*TP*AP*6FKP*TP*CP*AP*TP*CP*AP*CP)-3', 5'-D(*GP*TP*GP*AP*TP*GP*AP*CP*GP*TP*AP*GP*AP*GP)-3', RAD14, ... | | Authors: | Simon, N, Ebert, C, Schneider, S. | | Deposit date: | 2016-04-18 | | Release date: | 2016-06-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
Chemistry, 22, 2016
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3KMP
 | | Crystal Structure of SMAD1-MH1/DNA complex | | Descriptor: | 5'-D(P*AP*TP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*AP*TP*A)-3', 5'-D(P*GP*TP*AP*TP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*A)-3', GLYCEROL, ... | | Authors: | Baburajendran, N, Palasingam, P, Narasimhan, K, Jauch, R, Kolatkar, P.R. | | Deposit date: | 2009-11-11 | | Release date: | 2010-02-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.
Nucleic Acids Res., 38, 2010
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1NH2
 | | Crystal structure of a yeast TFIIA/TBP/DNA complex | | Descriptor: | 5'-D(*GP*TP*TP*TP*TP*AP*TP*AP*TP*AP*CP*AP*TP*AP*CP*A)-3', 5'-D(*TP*GP*TP*AP*(5IU)P*GP*TP*AP*TP*AP*(5IU)P*AP*AP*AP*AP*C)-3', Transcription initiation factor IIA large chain, ... | | Authors: | Bleichenbacher, M, Tan, S, Richmond, T.J. | | Deposit date: | 2002-12-18 | | Release date: | 2003-10-21 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes.
J.Mol.Biol., 332, 2003
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4BG7
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4FS2
 | | Base pairing mechanism of N2,3-ethenoguanine with dCTP by human polymerase iota | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*TP*(EFG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA polymerase iota, ... | | Authors: | Zhao, L. | | Deposit date: | 2012-06-26 | | Release date: | 2012-08-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases.
J.Biol.Chem., 287, 2012
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4O64
 | | Zinc fingers of KDM2B | | Descriptor: | Lysine-specific demethylase 2B, UNKNOWN ATOM OR ION, ZINC ION | | Authors: | Liu, K, Xu, C, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-12-20 | | Release date: | 2014-04-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
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2L7D
 | | Ribonucleotide Perturbation of DNA Structure: Solution Structure of [d(CGC)r(G)d(AATTCGCG)]2 | | Descriptor: | 5'-D(*CP*GP*C)-R(P*G)-D(P*AP*AP*TP*TP*CP*GP*CP*G)-3' | | Authors: | DeRose, E.F, Perera, L, Murray, M.S, Kunkel, T.A, London, R.E. | | Deposit date: | 2010-12-07 | | Release date: | 2011-06-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Dickerson DNA dodecamer containing a single ribonucleotide.
Biochemistry, 51, 2012
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6OPM
 | | Casposase bound to integration product | | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, DNA 21-mer, ... | | Authors: | Dyda, F, Hickman, A.B, Kailasan, S. | | Deposit date: | 2019-04-25 | | Release date: | 2020-02-12 | | Last modified: | 2020-08-26 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas.
Elife, 9, 2020
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8BQ7
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6U90
 | | Crystal structure of DNMT3B(N779A)-DNMT3L in complex with CpGpT DNA | | Descriptor: | CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | | Authors: | Gao, L, Song, J. | | Deposit date: | 2019-09-06 | | Release date: | 2020-06-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.00081754 Å) | | Cite: | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
To Be Published
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8BVX
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