PDB: 66478 resultsInfo pagesStatus searchChemie searchBIRD

---

8OKP	Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_33 Descriptor: Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},15~{R})-10,13,15-trimethyl-17-oxidanylidene-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-28 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
8OLK	Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI_13 Descriptor: 1,2-ETHANEDIOL, Carbonic anhydrase 2, ZINC ION, ... Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-30 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
8OMP	Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI33 Descriptor: Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},15~{R})-10,13,15-trimethyl-17-oxidanylidene-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-31 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
6XKG	Crystal structure of 3-O-Sulfotransferase isoform 3 in complex with 8mer oligosaccharide with 6S sulfation Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ... Authors: Pedersen, L.C, Liu, J, Wander, R. Deposit date: 2020-06-26 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Deciphering the substrate recognition mechanisms of the heparan sulfate 3- O -sulfotransferase-3. Rsc Chem Biol, 2, 2021
6XL8	Crystal structure of 3-O-Sulfotransferase isoform 3 in complex with 8mer oligosaccharide with no 6S sulfation Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Heparan sulfate glucosamine 3-O-sulfotransferase 3A1, IODIDE ION, ... Authors: Pedersen, L.C, Liu, J, Wander, R. Deposit date: 2020-06-28 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Deciphering the substrate recognition mechanisms of the heparan sulfate 3- O -sulfotransferase-3. Rsc Chem Biol, 2, 2021
8Q7I	PCNA from Chaetomium thermophilum in complex with Fen1 peptide Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen, SODIUM ION Authors: Alphey, M.S, Wolford, C.B, MacNeill, S.A. Deposit date: 2023-08-16 Release date: 2023-12-13 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Canonical binding of Chaetomium thermophilum DNA polymerase delta / zeta subunit PolD3 and flap endonuclease Fen1 to PCNA. Front Mol Biosci, 10, 2023
6YLM	mCherry Descriptor: CHLORIDE ION, mCherry Authors: Myskova, J, Rybakova, M, Brynda, J, Lazar, J. Deposit date: 2020-04-07 Release date: 2020-12-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Directionality of light absorption and emission in representative fluorescent proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
6YLP	EGFP_in_Acidic_env Directionality of Optical Properties of Fluorescent Proteins Descriptor: PHOSPHATE ION, eGFP_in_Acidic_env Authors: Myskova, J, Rybakova, O, Brynda, J, Lazar, J. Deposit date: 2020-04-07 Release date: 2020-12-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Directionality of light absorption and emission in representative fluorescent proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
6YLQ	EGFP in neutral pH, Directionality of Optical Properties of Fluorescent Proteins Descriptor: GLYCEROL, MAGNESIUM ION, eGFP Authors: Myskova, J, Rybakova, M, Brynda, J, Lazar, J. Deposit date: 2020-04-07 Release date: 2020-12-16 Last modified: 2021-01-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Directionality of light absorption and emission in representative fluorescent proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
6Y04	Crystal structure of beta-carbonic anhydrase isoform I (TvaCA1) from the Trichomonas vaginalis protozoan. Descriptor: Carbonic anhydrase, ZINC ION Authors: Di Fiore, A, De Simone, G. Deposit date: 2020-02-06 Release date: 2020-07-08 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase fromTrichomonas vaginalis. J Enzyme Inhib Med Chem, 35, 2020
7N4Z	Complex structure of NOS4 with noscapine Descriptor: NOS4, SULFATE ION, noscapine Authors: Kim, W, Zhang, Y. Deposit date: 2021-06-04 Release date: 2022-06-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Using fungible biosensors to evolve improved alkaloid biosyntheses. Nat.Chem.Biol., 18, 2022
7N53	Complex structure of PAP4 with papaverine Descriptor: 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE, GLYCEROL, PAP4, ... Authors: Kim, W, Zhang, Y. Deposit date: 2021-06-04 Release date: 2022-06-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Using fungible biosensors to evolve improved alkaloid biosyntheses. Nat.Chem.Biol., 18, 2022
7N54	Complex structure of GLAU4 with glaucine Descriptor: GLAU4, SULFATE ION, glaucine Authors: Kim, W, Zhang, Y. Deposit date: 2021-06-04 Release date: 2022-06-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Using fungible biosensors to evolve improved alkaloid biosyntheses. Nat.Chem.Biol., 18, 2022
8QV4	Hexameric HIV-1 CA in complex with DDD01728503 Descriptor: 1,2-ETHANEDIOL, Spacer peptide 1, ethyl 2-(3-oxidanylidene-2,4-dihydroquinoxalin-1-yl)ethanoate Authors: Petit, A.P, Fyfe, P.K. Deposit date: 2023-10-17 Release date: 2024-03-27 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments. Chemmedchem, 19, 2024
7ST5	Structure of Fab CC-95251 in complex with SIRP-alpha Descriptor: 1,2-ETHANEDIOL, Fab CC-95251 anti-SIRP-alpha heavy chain, Fab CC-95251 anti-SIRP-alpha light chain, ... Authors: Fenalti, G. Deposit date: 2021-11-12 Release date: 2023-05-17 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery and Preclinical Activity of BMS-986351, an Antibody to SIRP alpha That Enhances Macrophage-mediated Tumor Phagocytosis When Combined with Opsonizing Antibodies. Cancer Res Commun, 4, 2024
6YJM	Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with the Inhibitor GLPG1972 Descriptor: (5~{S})-5-[3-[(3~{S})-4-[3,5-bis(fluoranyl)phenyl]-3-methyl-piperazin-1-yl]-3-oxidanylidene-propyl]-5-cyclopropyl-imidazolidine-2,4-dione, A disintegrin and metalloproteinase with thrombospondin motifs 5, CALCIUM ION, ... Authors: Goepfert, A, Leonard, P, Triballeau, N, Fleury, D, Mollat, P, Lamers, M. Deposit date: 2020-04-03 Release date: 2021-04-14 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Discovery of GLPG1972/S201086, a Potent, Selective, and Orally Bioavailable ADAMTS-5 Inhibitor for the Treatment of Osteoarthritis. J.Med.Chem., 64, 2021
8OLF	Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor BS1982 Descriptor: Carbonic anhydrase 2, ZINC ION, [(8~{S},9~{S},13~{S},14~{S})-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-30 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
8OKJ	Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_12 Descriptor: Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{S},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-28 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
8OLA	Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor VK4 Descriptor: Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-30 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
8OMH	Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl (BS1982) Descriptor: Carbonic anhydrase 2, ZINC ION, [(8~{S},9~{S},13~{S},14~{S})-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-31 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
8OKO	Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_2 Descriptor: Carbonic anhydrase 2, ZINC ION, [(3~{S},8~{S},9~{S},10~{R},13~{S},14~{S})-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-28 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
8OKT	Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor VK42 Descriptor: Carbonic anhydrase 2, ZINC ION, [(8~{R},9~{S},13~{S},14~{S})-13-methyl-17-oxidanylidene-7,8,9,11,12,14,15,16-octahydro-6~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-29 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published
8OLM	Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl AKI1 Descriptor: Carbonic anhydrase 2, ZINC ION, [(3~{S},5~{S},8~{S},13~{R},14~{R})-5,14-dimethyl-16-oxidanylidene-1,2,3,4,6,7,8,11,12,13,15,17-dodecahydrocyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-30 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
8OMB	Carbonic Anhydrase 2 in Complex with Steriod_Sulphamoyl VK42 Descriptor: Carbonic anhydrase 2, ZINC ION, [(8~{R},9~{S},13~{S},14~{S})-13-methyl-17-oxidanylidene-7,8,9,11,12,14,15,16-octahydro-6~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-31 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Carbonic Anhydrase in Complex with Steriod_Sulphamoyl To Be Published
8OMN	Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl VK4 Descriptor: Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate Authors: Brynda, J, Rezacova, P.M, Kudova, E. Deposit date: 2023-03-31 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl To Be Published

<294295296297298299300301302303304305306307308309>