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8PQV
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BU of 8pqv by Molmil
Cytoplasmic dynein-1 motor domain in post-powerstroke state
Descriptor: Cytoplasmic dynein 1 heavy chain 1
Authors:Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P.
Deposit date:2023-07-12
Release date:2024-03-27
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
8PQZ
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BU of 8pqz by Molmil
Cytoplasmic dynein-1 A1/A2 motor domains bound to LIS1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ...
Authors:Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P.
Deposit date:2023-07-12
Release date:2024-03-27
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
7KEK
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BU of 7kek by Molmil
Structure of the free outer-arm dynein in pre-parallel state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ...
Authors:Rao, Q, Zhang, K.
Deposit date:2020-10-11
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
7MGM
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BU of 7mgm by Molmil
Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lahiri, I, Reimer, J.M, Leschziner, A.E.
Deposit date:2021-04-12
Release date:2022-01-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for cytoplasmic dynein-1 regulation by Lis1.
Elife, 11, 2022
7MI8
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BU of 7mi8 by Molmil
Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5
Descriptor: Fusion protein of Dynein and Endolysin
Authors:Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI6
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BU of 7mi6 by Molmil
Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1
Descriptor: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
Authors:Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI3
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BU of 7mi3 by Molmil
Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4
Descriptor: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
Authors:Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI1
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BU of 7mi1 by Molmil
X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound (compound 20)
Descriptor: Chimera protein of Dynein and Endolysin
Authors:Santarossa, C.C, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MOQ
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BU of 7moq by Molmil
The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ...
Authors:Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H.
Deposit date:2021-05-03
Release date:2021-07-14
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM.
Embo Rep., 22, 2021
7KZM
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BU of 7kzm by Molmil
Outer dynein arm bound to doublet microtubules from C. reinhardtii
Descriptor: DC1, DC2, Dynein 11 kDa light chain, ...
Authors:Walton, T, Wu, H, Brown, A.B.
Deposit date:2020-12-10
Release date:2021-01-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
7KZO
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BU of 7kzo by Molmil
Outer dynein arm docking complex bound to doublet microtubules from C. reinhardtii
Descriptor: Dynein gamma chain, flagellar outer arm, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Walton, T, Wu, H, Brown, A.B.
Deposit date:2020-12-10
Release date:2021-01-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
7KZN
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BU of 7kzn by Molmil
Outer dynein arm core subcomplex from C. reinhardtii
Descriptor: DC1, DC2, Dynein 11 kDa light chain, ...
Authors:Walton, T, Wu, H, Brown, A.B.
Deposit date:2020-12-10
Release date:2021-01-20
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
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